ADVANCED PATHOPHYSIOLOGY EXAM 2 FINAL PAPER TESTED QUESTIONS WITH 100 PERCENT CORRECT ANSWERS

ADVANCED PATHOPHYSIOLOGY EXAM 2
FINAL PAPER TESTED QUESTIONS WITH 100
PERCENT CORRECT ANSWERS


◉ Autosomal Recessive
Answer: two copies of an abnormal gene must be present in order
for the phenotype to be expressed
2 copies of the gene mutation for the offspring to inherit
both parents have to have the autosomal recessive gene


◉ X-linked dominant
Answer: dominant trait or disorder caused by a mutation in a gene
on the X chromosome
phenotype expressed in females and males
most of the time the offspring does not survive


◉ x-linked recessive
Answer: mutation in a gene on the X chromosome causes the
phenotype to be expressed in males who inherit the gene as well as
females who are homozygous for the mutation
carrier females do not express phenotype

,◉ A mother is a carrier for x-linked recessive Emery-Dreifuss
muscular dystrophy gene. The father has not been tested but does
not exhibit the phenotype that would normally be showing at his age
(upper and lower extremity weakness, soreness, and arrhythmias).
What does their offspring chance of inheritance look like?
a. Non-carriers 50%, Carrier 25%, Affected 25%
b. Non-carriers 25%, Carrier 50%, Affected 25%
c. Non-carriers 25%, Carrier 25%, Affected 25%
d. Affected 50%, Non-affected 25%
Answer: a


◉ If two heterozygous individuals mated and their first three
children expressed a phenotype for a dominant trait, which of the
following would be true?
a) their next child would have the dominant trait
b) their next child would have the recessive trait
c) there is a 25% chance their next child would show the recessive
trait
d) they cannot have a child with the recessive trait
Answer: c


◉ In an autosomal dominant disorder, mom is affected, father is
unaffected. The inheritance chance for offspring is:

,a. Affected 50%, Unaffected 50%
b. Affected 25%, Unaffected 75%
c. Affected 75%, Unaffected 25%
d. Affected 100%, Unaffected 0%
Answer: a


◉ In an autosomal recessive disorder, mom is non-carrier, father is
affected. The offspring's chance of inheritance is:
a. Carrier 25%, Non-carrier 75%, Affected 0%
b. Carrier 25%, Non-carrier 25%, Affected 50%
c. Carrier 100%, Affected 0%
d. Carrier 75%, Non-carrier 25%, Affected 0%
Answer: c


◉ In an autosomal recessive disorder, mom is carrier, father is
affected. The offspring's chance of inheritance is:
a. Carrier 25%, Non-carrier 75%, Affected 0%
b. Carrier 25%, Non-carrier 25%, Affected 50%
c. Carrier 25%, Affected 75%
d. Carrier 50%, Affected 50%
Answer: d

, ◉ In an x-linked dominant disorder, mom is affected, father is
unaffected. The offspring's chance of inheritance is:
a. Carrier 25%, Non-carrier 75%, Affected 0%
b. Affected 50%, Non-affected 50%
c. Affected 75%, Non-affected 25%
d. None of the above
Answer: B


◉ In an x-linked dominant disorder, mom is affected, father is
affected. The offspring's chance of inheritance is:
a. Affected 25%, Non-affected 25%
b. Affected 50%, Non-affected 50%
c. Affected 100%, Non-affected 0%
d. Affected 75%, Non-affected 25%
Answer: d


◉ In an x-linked recessive disorder, mom is affected, father is non-
carrier. The offspring's chance of inheritance is:
a. Non-carrier 25%, Carrier 25%, Affected 50%
b. Non-carriers 0%, Carrier 50%, Affected 50%
c. Non-carrier 25%, Carrier 25%, Affected 50%
Answer: b