ADVANCED PATHOPHYSIOLOGY EXAM 2
COMPREHENSIVE EXAM STUDY GUIDE
SOLVED QUESTIONS WITH VERIFIED
ANSWERS
◉ Abnormalities in which immature precursor leukocyte cells are
associated with leukemia are known as:
A) bands.
B) blasts.
C) reticulocytes.
D) granulocytes.
Answer: Ans: B
◉ A 5-year-old child is brought in by his parents who report that she
has not been eating well, and they think she is losing weight even
though her belly looks bloated. They also noticed that she is limping
when she walks. Physical examination reveals a pale, quiet girl.
Small bruises are noted on her shins and upper arms. Her heart
sounds and lung sounds are normal. She has hepatomegaly and
splenomegaly. The remainder of the exam is normal. Which type of
hematologic cancer should be suspected?
A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
,C) Myeloblastic syndrome
D) Non-Hodgkin lymphoma
Answer: Ans: A
◉ Iron-deficiency anemia is characterized by red blood cells that
are:
A) normocytic and normochromic.
B) microcytic and hypochromic.
C) macrocytic and normochromic.
D) microcytic and normochromic.
Answer: Ans: B
◉ A 60-year-old woman is diagnosed with iron deficiency anemia.
The transferrin level is high with this type of anemia because:
A) the microcytic RBCs are defective.
B) there is not enough iron to bind.
C) the body is trying to deliver more iron.
D) more iron is stored.
Answer: Ans: C
◉ A 5-year-old male child has a bleeding disease that is
characterized by areas of hemorrhage in the joints and muscles after
, minor injuries. Laboratory tests reveal a deficiency of a coagulation
factor active
in the early phase of blood coagulation (formation of intrinsic
thromboplastin). What is the most likely diagnosis?
A) Thrombocytopenia
B) Hemophilia
C) Disseminated intravascular coagulation syndrome
D) Protein C deficiency
Answer: Ans: B
◉ A 55-year-old woman has a hypochromic, microcytic anemia. The
most likely cause is:
A) vitamin B12 or folic acid deficiency.
B) hemolysis of red blood cells due to autoantibodies.
C) iron deficiency resulting from chronic gastrointestinal blood loss.
D) replacement of bone marrow by metastatic tumor.
Answer: Ans: C
◉ Which of the following is a common feature of all forms of
leukemia?
A) Reduction in leukocytes leading to bone marrow destruction
B) Proliferation of malignant lymphocytes altering leukocyte
production
COMPREHENSIVE EXAM STUDY GUIDE
SOLVED QUESTIONS WITH VERIFIED
ANSWERS
◉ Abnormalities in which immature precursor leukocyte cells are
associated with leukemia are known as:
A) bands.
B) blasts.
C) reticulocytes.
D) granulocytes.
Answer: Ans: B
◉ A 5-year-old child is brought in by his parents who report that she
has not been eating well, and they think she is losing weight even
though her belly looks bloated. They also noticed that she is limping
when she walks. Physical examination reveals a pale, quiet girl.
Small bruises are noted on her shins and upper arms. Her heart
sounds and lung sounds are normal. She has hepatomegaly and
splenomegaly. The remainder of the exam is normal. Which type of
hematologic cancer should be suspected?
A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
,C) Myeloblastic syndrome
D) Non-Hodgkin lymphoma
Answer: Ans: A
◉ Iron-deficiency anemia is characterized by red blood cells that
are:
A) normocytic and normochromic.
B) microcytic and hypochromic.
C) macrocytic and normochromic.
D) microcytic and normochromic.
Answer: Ans: B
◉ A 60-year-old woman is diagnosed with iron deficiency anemia.
The transferrin level is high with this type of anemia because:
A) the microcytic RBCs are defective.
B) there is not enough iron to bind.
C) the body is trying to deliver more iron.
D) more iron is stored.
Answer: Ans: C
◉ A 5-year-old male child has a bleeding disease that is
characterized by areas of hemorrhage in the joints and muscles after
, minor injuries. Laboratory tests reveal a deficiency of a coagulation
factor active
in the early phase of blood coagulation (formation of intrinsic
thromboplastin). What is the most likely diagnosis?
A) Thrombocytopenia
B) Hemophilia
C) Disseminated intravascular coagulation syndrome
D) Protein C deficiency
Answer: Ans: B
◉ A 55-year-old woman has a hypochromic, microcytic anemia. The
most likely cause is:
A) vitamin B12 or folic acid deficiency.
B) hemolysis of red blood cells due to autoantibodies.
C) iron deficiency resulting from chronic gastrointestinal blood loss.
D) replacement of bone marrow by metastatic tumor.
Answer: Ans: C
◉ Which of the following is a common feature of all forms of
leukemia?
A) Reduction in leukocytes leading to bone marrow destruction
B) Proliferation of malignant lymphocytes altering leukocyte
production
