RN HESI PHARMACOLOGY WITH NGN TEST
PRACTICE ASSESSMENT 2026 FULL
QUESTIONS AND ANSWERS GRADED A PLUS
COMPLETE REVISION GUIDE
◉ A client with viral influenza is receiving vitamin C, 1000 mg PO
daily, and acetaminophen elixir, 650 mg PO every 4 hours PRN. The
nurse calls the health care provider to report that the client has
developed diarrhea. Which change in prescriptions should the nurse
anticipate?
A. Change the acetaminophen to ibuprofen.
B. Change the elixir to an injectable route.
C. Decrease the dose of vitamin C.
D. Begin treatment with an antibiotic..
Answer: C. Decrease the dose of vitamin C.
◉ When providing nursing care for a client receiving pyridostigmine
bromide for myasthenia gravis, which nursing intervention has the
highest priority?
A. Monitor the client frequently for urinary retention.
B. Assess respiratory status and breath sounds often.
,C. Monitor blood pressure each shift to screen for hypertension.
D. Administer most medications after meals to decrease
gastrointestinal irritation..
Answer: B. Assess respiratory status and breath sounds often.
◉ A client with a dislocated shoulder is being prepared for a closed
manual reduction using conscious sedation. Which medication
should the nurse explain as a sedative used during the procedure?
A.Inhaled nitrous oxide
B.Midazolam IV
C.Ketamine IM
D.Fentanyl and droperidol IM.
Answer: B. Midazolam IV
◉ A client is being discharged with a prescription for sulfasalazine
to treat ulcerative colitis. Which instruction should the nurse
provide to this client prior to discharge?
A. Maintain good oral hygiene.
B. Take the medication 30 minutes before a meal.
C. Discontinue use of the drug gradually.
D. Drink at least eight glasses of fluid a day..
,Answer: D. Drink at least eight glasses of fluid a day.
◉ The health care provider prescribes carbamazepine for a child
whose tonic-clonic seizures have been poorly controlled. The nurse
informs the mother that the child must have blood tests every week.
The mother asks why so many blood tests are necessary. Which
complication is assessed through frequent laboratory testing that
the nurse should explain to this mother?
A. Nephrotoxicity
B. Ototoxicity
C. Myelosuppression
D.Hepatotoxicity.
Answer: C. Myelosuppression
Myelosuppression is the highest priority complication that can
potentially affect clients managed with carbamazepine therapy. The
client requires close monitoring for this condition by weekly
laboratory testing. Hepatic function may be altered, but this
complication does not have as great a potential for occurrence as
option C. Options A and B are not typical complications of
carbamazepine therapy.
◉ When developing a written nursing care plan for a client receiving
chemotherapy for treatment of cancer, the nurse writes, "Assess each
, voiding for hematuria." The administration of which type of
chemotherapeutic agent would prompt the nurse to add this
intervention?
A. Vincristine
B. Bleomycin sulfate
C. Chlorambucil
D. Cyclophosphamide.
Answer: D. Cyclophosphamide
Hemorrhagic cystitis is the characteristic adverse reaction of
cyclophosphamide. Administration of options A, B, and C does not
typically cause hemorrhagic cystitis.
◉ A client is receiving oral griseofulvin for a persistent tinea
corporis infection. Which response by the client indicates an
accurate understanding of the drug teaching conducted by the
nurse?
A. "I'll wear sunscreen whenever I mow the lawn."
B. "This is the worse bacterial infection I've ever had."
C. "I will need to take the medication for 7 days."
D. "My urine will probably turn brown due to this drug.".
Answer: A. "I'll wear sunscreen whenever I mow the lawn."
PRACTICE ASSESSMENT 2026 FULL
QUESTIONS AND ANSWERS GRADED A PLUS
COMPLETE REVISION GUIDE
◉ A client with viral influenza is receiving vitamin C, 1000 mg PO
daily, and acetaminophen elixir, 650 mg PO every 4 hours PRN. The
nurse calls the health care provider to report that the client has
developed diarrhea. Which change in prescriptions should the nurse
anticipate?
A. Change the acetaminophen to ibuprofen.
B. Change the elixir to an injectable route.
C. Decrease the dose of vitamin C.
D. Begin treatment with an antibiotic..
Answer: C. Decrease the dose of vitamin C.
◉ When providing nursing care for a client receiving pyridostigmine
bromide for myasthenia gravis, which nursing intervention has the
highest priority?
A. Monitor the client frequently for urinary retention.
B. Assess respiratory status and breath sounds often.
,C. Monitor blood pressure each shift to screen for hypertension.
D. Administer most medications after meals to decrease
gastrointestinal irritation..
Answer: B. Assess respiratory status and breath sounds often.
◉ A client with a dislocated shoulder is being prepared for a closed
manual reduction using conscious sedation. Which medication
should the nurse explain as a sedative used during the procedure?
A.Inhaled nitrous oxide
B.Midazolam IV
C.Ketamine IM
D.Fentanyl and droperidol IM.
Answer: B. Midazolam IV
◉ A client is being discharged with a prescription for sulfasalazine
to treat ulcerative colitis. Which instruction should the nurse
provide to this client prior to discharge?
A. Maintain good oral hygiene.
B. Take the medication 30 minutes before a meal.
C. Discontinue use of the drug gradually.
D. Drink at least eight glasses of fluid a day..
,Answer: D. Drink at least eight glasses of fluid a day.
◉ The health care provider prescribes carbamazepine for a child
whose tonic-clonic seizures have been poorly controlled. The nurse
informs the mother that the child must have blood tests every week.
The mother asks why so many blood tests are necessary. Which
complication is assessed through frequent laboratory testing that
the nurse should explain to this mother?
A. Nephrotoxicity
B. Ototoxicity
C. Myelosuppression
D.Hepatotoxicity.
Answer: C. Myelosuppression
Myelosuppression is the highest priority complication that can
potentially affect clients managed with carbamazepine therapy. The
client requires close monitoring for this condition by weekly
laboratory testing. Hepatic function may be altered, but this
complication does not have as great a potential for occurrence as
option C. Options A and B are not typical complications of
carbamazepine therapy.
◉ When developing a written nursing care plan for a client receiving
chemotherapy for treatment of cancer, the nurse writes, "Assess each
, voiding for hematuria." The administration of which type of
chemotherapeutic agent would prompt the nurse to add this
intervention?
A. Vincristine
B. Bleomycin sulfate
C. Chlorambucil
D. Cyclophosphamide.
Answer: D. Cyclophosphamide
Hemorrhagic cystitis is the characteristic adverse reaction of
cyclophosphamide. Administration of options A, B, and C does not
typically cause hemorrhagic cystitis.
◉ A client is receiving oral griseofulvin for a persistent tinea
corporis infection. Which response by the client indicates an
accurate understanding of the drug teaching conducted by the
nurse?
A. "I'll wear sunscreen whenever I mow the lawn."
B. "This is the worse bacterial infection I've ever had."
C. "I will need to take the medication for 7 days."
D. "My urine will probably turn brown due to this drug.".
Answer: A. "I'll wear sunscreen whenever I mow the lawn."
