Complete Study Guide | Verified Questions
& Correct Answers with Detailed Rationales
| Advanced Practice Exam Prep
CMN 574 EXAM 1 STUDY GUIDE 2025/2026
• This study guide contains 200 verified practice exam questions with complete
correct answers and detailed clinical rationales designed to ensure comprehensive
mastery of chest pain assessment and management.
• Use this material by working through questions systematically, reviewing
rationales thoroughly, and testing yourself repeatedly until you achieve consistent
accuracy across all topic areas.
QUESTION 1
What is the most common cause of chest pain in musculoskeletal (MSK)
presentations?
A) Broken rib
B) Herpes zoster
C) Muscle strain and costochondritis
D) Fibromyalgia
E) Chest wall contusion
CORRECT ANSWER: C) Muscle strain and costochondritis
Rationale: Muscle strain and costochondritis represent the most frequent etiology
of MSK-related chest pain in clinical practice. These conditions result from muscular
overuse, inflammation of the costochondral junctions, or trauma to the chest wall
musculature. While other MSK conditions can cause chest pain, the prevalence and
incidence data consistently demonstrate that simple muscle strain and
costochondritis account for the majority of MSK chest pain presentations in primary
care and urgent care settings.
,QUESTION 2
A 28-year-old active patient presenting with chest pain after weightlifting
most likely has which condition?
A) Pulmonary embolism
B) Acute myocardial infarction
C) MSK chest pain related to sports activity with lifting
D) Spontaneous pneumothorax
E) Aortic dissection
CORRECT ANSWER: C) MSK chest pain related to sports activity with lifting
Rationale: Young active patients who engage in sports with weightlifting frequently
develop MSK chest pain due to muscular strain and microtrauma to the chest wall
structures. The direct correlation between the activity (weightlifting) and symptom
onset is a classic presentation of MSK etiology. Young age, high activity level, and
the temporal relationship to specific physical activity make serious cardiac or
pulmonary pathology unlikely, though these must always be ruled out clinically.
QUESTION 3
Which of the following is the most common risk factor for MSK chest pain?
A) Sedentary lifestyle
B) Advanced age
C) Trauma and overuse
D) Chronic heart disease
E) Pulmonary hypertension
CORRECT ANSWER: C) Trauma and overuse
,Rationale: Trauma and overuse are the primary risk factors for developing MSK
chest pain. Repetitive physical activities, sudden injury to the chest wall, poor
posture, and strenuous exercise all predispose individuals to muscle strain and
costochondritis. These mechanical factors are far more prevalent causes of MSK
chest pain than systemic or cardiac conditions.
QUESTION 4
A patient reports chest pain after a motor vehicle accident. What is the
primary risk factor evident in this scenario?
A) Infection
B) Metabolic disorder
C) Trauma
D) Autoimmune condition
E) Genetic predisposition
CORRECT ANSWER: C) Trauma
Rationale: Direct trauma from a motor vehicle accident is a clear and significant risk
factor for MSK chest pain. Traumatic injury can cause muscle contusion, rib
fractures, costochondral joint inflammation, and soft tissue damage. This scenario
exemplifies how acute traumatic events precipitate MSK chest pain presentations.
QUESTION 5
Which infection history is relevant when evaluating MSK chest pain risk
factors?
A) History of tuberculosis
B) History of chicken pox (herpes zoster reactivation risk)
C) History of pneumonia
D) History of influenza
, E) History of meningitis
CORRECT ANSWER: B) History of chicken pox (herpes zoster reactivation
risk)
Rationale: A history of chicken pox (varicella) is clinically significant because it
indicates previous infection with varicella-zoster virus, which can reactivate as
herpes zoster (shingles). Herpes zoster can present with severe chest wall pain and
is an important differential diagnosis when evaluating MSK-type chest pain. The
infection history helps identify patients at risk for this particular etiology.
QUESTION 6
What are the characteristic signs and symptoms of MSK chest pain?
A) Sudden onset with associated dyspnea and diaphoresis
B) Gradual onset of sharp to dull pain that is localized and reproducible with arm
movement and deep inspiration
C) Pleuritic pain with fever and productive cough
D) Diffuse chest pressure relieved by sitting upright
E) Severe pain radiating to the left arm with ST elevation
CORRECT ANSWER: B) Gradual onset of sharp to dull pain that is localized
and reproducible with arm movement and deep inspiration
Rationale: MSK chest pain characteristically presents with a gradual onset of sharp-
to-dull quality pain that is well-localized to a specific area of the chest wall. A key
distinguishing feature is reproducibility: the pain can be elicited or worsened with
arm movement, palpation, or deep inspiration. These clinical features differentiate
MSK pain from cardiac ischemia, pulmonary embolism, or other serious
pathologies that typically present differently.
QUESTION 7