COMPLETE QUESTIONS AND ANSWERS
◉ Hormone.
Answer: A natural substance that is produced in the body that
influences the way the body grows or develops
- Or a drug that is synthesized within the body
- Ex.) Cortisol, testosterone ect
◉ Xenobiotic.
Answer: A chemical compound that is foreign to a living organism
◉ Toxin.
Answer: Poisons of biologic origin (ex. snake/ spider venom,
botulinum toxin)
- Produce harmful effects
◉ Toxicant.
Answer: Poisons from non-biological origin
- Ex.) Lead, pharmaceuticals ect
,◉ Toxicology.
Answer: Study of harmful or poisonous effects of drugs
◉ Agonists.
Answer: Drugs that bind to and either directly or indirectly activate
the receptor
◉ Agonist.
Answer: Albuterol, which binds to bronchial smooth muscles and
relaxes them is an example of a ________
◉ Affinity.
Answer: How tightly a drug binds to the receptor
◉ Potency.
Answer: The amount of drug necessary to elicit a response
◉ High.
Answer: _________ potency = smaller effective dose
◉ Fentanyl.
, Answer: Since morphine is dosed in milligrams and fentanyl is dosed
in micrograms, ________ is more potent
◉ Efficacy.
Answer: A drug's ability to produce the maximal desired response
◉ Efficacy.
Answer: Is efficacy or potency more important to clinically
determine a drug's usefulness?
◉ Equi-potency.
Answer: The relative doses of two drugs to get the same efficacy
◉ Equipotent, drug B.
Answer: If you take 100mg of drug A and 10mg of dose B to get the
same effect, these drugs are considered _________
- Which drug is more potent?
◉ Full Agonist.
Answer: Produces a full response at full receptor occupancy
- If you bind 100% of receptors, you get 100% effects
- Ex.) Using methadone on a patient who has overdosed on a drug