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Comprehensive Review: Rheumatology & Chest Pain Differential
Question 1. Which of the following is the most common cause of chest
pain?
A. Gastrointestinal
B. Musculoskeletal
C. Psychiatric
D. Respiratory
Correct Answer: B
Rationale: According to the study guide, musculoskeletal (MSK) chest pain
is the most common cause of chest pain, including muscle strain,
costochondritis, and broken ribs.
Question 2. A young, active patient presents with chest pain after playing
sports. This clinical scenario is most consistent with which etiology?
A. Gastrointestinal
B. Psychiatric
,C. Musculoskeletal
D. Cardiac
Correct Answer: C
Rationale: The study guide specifically mentions that MSK chest pain is
seen in young active patients, particularly after sports or vigorous activity.
Question 3. Which of the following is a risk factor for musculoskeletal
chest pain?
A. History of ulcers
B. Smoking
C. History of chicken pox
D. NSAID use
Correct Answer: C
Rationale: The study guide lists a history of chicken pox (which can lead to
herpes zoster) as a risk factor for MSK chest pain, along with trauma and
overuse.
Question 4. A patient describes their chest pain as gradual in onset, sharp
to dull in quality, and localized to a specific area they can point to with
one finger. This presentation is most consistent with:
A. Gastroesophageal reflux disease
B. Musculoskeletal chest pain
C. Pulmonary embolism
,D. Panic disorder
Correct Answer: B
Rationale: MSK chest pain is characterized by gradual onset, sharp-dull
quality, localized pain where the patient can point with one finger, and
reproducibility with movement or deep inspiration.
Question 5. Which diagnostic test is indicated for musculoskeletal chest
pain in a patient with a history of trauma?
A. ECG
B. Chest X-ray
C. EGD
D. D-dimer
Correct Answer: B
Rationale: The study guide states that no tests are typically needed for
MSK chest pain unless there is a history of trauma, in which case a chest
X-ray is indicated.
Question 6. First-line treatment for musculoskeletal chest pain includes all
of the following EXCEPT:
A. Rest
B. NSAIDs
C. Ice/Heat
D. Prednisone
, Correct Answer: D
Rationale: Treatment for MSK chest pain includes rest, NSAIDs, and
ice/heat. Corticosteroids like prednisone are not first-line for MSK chest
pain.
Question 7. Which gastrointestinal condition is NOT listed as a cause of GI
chest pain?
A. GERD
B. Esophagitis
C. Pancreatitis
D. Hiatal hernia
Correct Answer: C
Rationale: The study guide lists GERD, esophagitis/esophaeal spasm, PUD,
and hiatal hernia as GI causes of chest pain. Pancreatitis is not mentioned.
Question 8. Which of the following is the second most common cause of
chest pain?
A. Musculoskeletal
B. Gastrointestinal
C. Psychiatric
D. Respiratory