NR565 ADVANCED PHARMACOLOGY WEEK 5 STUDY GUIDE | PRACTICE QUESTIONS &
ANSWERS | COMPREHENSIVE EXAM REVIEW 2026/2027
Thyroid
o What labs are used to diagnose?
o Timeframe for re-check of labs after starting levothyroxine - ANS ✔✔TSH, Free T4, T3
6 week check up after initiation
12 month check up once therapeutic
Treatment of thyroid storm - ANS ✔✔PTU is the preferred treatment for thyroid storm
Signs and symptoms of hypo and hyperthyroidism - ANS ✔✔Hyper:
-weight loss
-tachycardia
-trouble sleeping
-increase body temp
-exophthalmos
Hypo:
-fatigue
-weight gain
-depression
-bradycardia
-dry skin/hair
Result of not treating hypothyroidism during pregnancy - ANS ✔✔Can result in permanent
neuropsychological deficits in neonate primarily in first trimester.
, Medication to treat symptoms of hyperthyroidism (notice this is treating symptoms and not the
hyperthyroidism itself) - ANS ✔✔Metoprolol is used to treat tachycardia associated with
hyperthyroidism
Drug/Food/Supplement interactions with levothyroxine - ANS ✔✔Phenytoin
Carbamazepine
Rifampin
Sertraline
Phenobarbital
Warfarin
Catecholamines
Calcium
Diabetes
-How to confirm a diagnosis prior to beginning treatment - ANS ✔✔-Acute symptoms of
diabetes plus casual plasma glucose concentration greater than or equal to 200 mg/dL
-Fasting plasma glucose greater than or equal to 126 mg/dL
-2 hour post-load plasma glucose in an oral glucose tolerance test greater than or equal to 200
mg/dL. The test uses a glucose load containing the equivalent of 75 g anhydrous glucose
dissolved in water
-HgbA1c greater than or equal to 6.5%
o A1C
-General goals
-Older Adult goal
-When should insulin be considered?
-At what time interval should it be re-checked? - ANS ✔✔-A1C goal of less than 7% indicates
normal
ANSWERS | COMPREHENSIVE EXAM REVIEW 2026/2027
Thyroid
o What labs are used to diagnose?
o Timeframe for re-check of labs after starting levothyroxine - ANS ✔✔TSH, Free T4, T3
6 week check up after initiation
12 month check up once therapeutic
Treatment of thyroid storm - ANS ✔✔PTU is the preferred treatment for thyroid storm
Signs and symptoms of hypo and hyperthyroidism - ANS ✔✔Hyper:
-weight loss
-tachycardia
-trouble sleeping
-increase body temp
-exophthalmos
Hypo:
-fatigue
-weight gain
-depression
-bradycardia
-dry skin/hair
Result of not treating hypothyroidism during pregnancy - ANS ✔✔Can result in permanent
neuropsychological deficits in neonate primarily in first trimester.
, Medication to treat symptoms of hyperthyroidism (notice this is treating symptoms and not the
hyperthyroidism itself) - ANS ✔✔Metoprolol is used to treat tachycardia associated with
hyperthyroidism
Drug/Food/Supplement interactions with levothyroxine - ANS ✔✔Phenytoin
Carbamazepine
Rifampin
Sertraline
Phenobarbital
Warfarin
Catecholamines
Calcium
Diabetes
-How to confirm a diagnosis prior to beginning treatment - ANS ✔✔-Acute symptoms of
diabetes plus casual plasma glucose concentration greater than or equal to 200 mg/dL
-Fasting plasma glucose greater than or equal to 126 mg/dL
-2 hour post-load plasma glucose in an oral glucose tolerance test greater than or equal to 200
mg/dL. The test uses a glucose load containing the equivalent of 75 g anhydrous glucose
dissolved in water
-HgbA1c greater than or equal to 6.5%
o A1C
-General goals
-Older Adult goal
-When should insulin be considered?
-At what time interval should it be re-checked? - ANS ✔✔-A1C goal of less than 7% indicates
normal
