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1. What is elevated in 80% of
CA-125
cases in women with ovarian
cancer?
adenocarcinoma
2. Exposure to someone else's
cig-arette smoke for a long
peri-
od of time may increase
the risk of lung cancer,
usually in in older post-menopausal women
?
3. When is mammography
more sensitive and
specific?
4. What are Reen-Sternberg cells? large cells with mirror image nuclei
5. What is the cause of early bone marrow failure:
bone marrow failure in acute
leukemia?
10. Which investigation is
6. Cite the name of a virus diagnostic for acute
that priduces leukemia: leukemia?
7. Cite 2 possible ways of
transmis-sion of HTLV-1:
8. What's the essential
diagnostic feature of acute
leukemia?
9. Cite the 3 manifestations of
, Oncology Final Exam with all Correct & 100% Verified Answers |
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crowding out of normal hematopoietic cells in
bone marrow eventually leads to bone marrow a hypercellular bone marrow with malignant
failure prolifera-tion of bone marrow blast cells ( > 30%
of bone marrow is replaced by blast cells)
HTLV-1
-fever due to infection (neutropenia)(WBCs)
-anemia due to encroachment of RBCs precursors
-from mother to child via childbirth -bleeding thrombocytopenia (ex: epistaxis)
-sexual contact
(platelets) bone marrow aspiration or biopsy
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11. Cite 3 bad prognostic leukemia?
conditions for acute
leukemis: 20. Cite the advantage of
Gleevec over other
chemo drug:
12. Why are antibiotics given
during the treatment of
acute leukemia?
13. Cite the name os an
antibiotic used in tx of acute
leukemis infec-tions:
14. Pneumonias caused by
fungal in-fections are treated
by:
15. Pneumonias caused by
Pneumo-cystitis carinii is
treated with:
16. Cite the name of an antiviral
med-ication (in infection in
leukemis):
17. What's the cause of tumor
lysis syndrome?
18. How is tumor lysis syndrom
sus-pected?
19. Cite the name of one drug
used for remission
induction of acute
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-hepatic or renal disfunction
-central nervous system involvement Zovirax or Valtrex
-high WBC count
because infection are serious in neutropenic tumor cell death after chemotherapy
immuno-suppressed patients
Fortaz in patients with large tumor burden who develop
acute renal failure after initial treatment
Predisone
Amphotericin B
Bactrim or Spectra it inhibits tyrosine kinase activity, promotes
apoptosis of leukemic cells
21. Tyrosine kinase inhibitors