Pharmacology Test 3 Maryville
NURS 615
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, High dose of Colchicine high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or
4.8mg total.
Difference between high dose and low dose Colchicine The difference between the two is low dose is as effective as high dose with a
lower side effect profile.
Lab values to monitor with Colchicine Check renal function test, BUN, Creatine
Patient education with Colchicine Almost always causes some degree of diarrhea, make sure patients are aware
of this side effect
Patient education with Febuxostat (Uloric) Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid Avoid beer, ale, & wine
deposits. Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
WHO 3 step ladder for pain medication
What is not a first line for pain medication? Narcotics
Recommendations for pain treatment You want to start with NSAIDs first and then work your way up from there.
types of Corticosteroid treatment Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work? Suppress the inflammatory & immune systems by inhibiting the synthesis of
chemical mediators.
what are the chemical mediators that Corticosteroids Prostaglandins, leukotrienes, & histamines
work on?
Corticosteroids and inflammation Decreases inflammation which decreases swelling, warmth, redness, & pain.
Uses for corticosteroid treatment Addison's disease, hormone replacement, cancer therapy
SLE, arthritis, IBD, & to suppress graft rejection