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RLAT QUESTIONS AND VERIFIED ANSWERS..

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RLAT QUESTIONS AND VERIFIED ANSWERS

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Common parasitic pathogens of concern (mice)


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-pinworms
-fur mites
-intentional parasite
-Demodex spp.




Monogamous breeding


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, 1 male and 1 female
Pros: record keeping easy and allows for post-parting breeding
Cons: need lots of males




LIVIM


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Lethal Intestinal Virus infection of Mice




Examples of barriers in the vivarium


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Doors
Hand sinks
Air locks
Anterooms
Change rooms
Autoclaves
Fumigation/ disinfection chambers
Disinfection transfer tanks (dunk tanks)
Constant air pressure differentials
HEPA filters




Common diseases of Zebrafish


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, Microsporidiosis (pseudoloma neurophilia )
Mycobacteriosis (Fish TB)- treat by bleaching eggs
Pseudocapillaria (nematode disease)- transmitted by ingestion of infected
fish, treat with ivermectin




Potential sources of water


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Municipal, wells (fresh or sea) or natural bodies of water




LCM


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Lymphocytic choriomeningitis




Frequency of opioid doses for rodents


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Buprenorphine- every 8 hours
Morphine-every 2 hours
Oxymorphone- every 4 hours
Meperidine- every hour

, Thigmotaxis


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response to touch




Typical air exchanges in IVC racks


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40-60 airs changes per hour




Inclusion barrier


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Prevent the escape of agents of disease from the animals in the unit to the
outside (bio safety)
And
Quarantine or isolate animals of unknown health status or to contain
animals intentionally infected with human or animal pathogens (bio
containment)




Rat water consumption daily


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