Nurs 5334 adv pharmacotherapeutics final review lehne s pharmacology end of module review
lOMoAR cPSD| 57629747
NURS 5334 Adv. Pharmacotherapeutics, Final Review -
Lehne's Pharmacology End Of Module Review
Questions & Answers (M1-M4)
Why do many medications lack pediatric dosing information in their drug
labeling?
A. Most medications are not used in pediatric patients.
B. There is a lack of evidence-based literature on the safe and effective use of
medications in children.
C. The FDA does not allow pediatric dosing information in product labeling.
D. Only products available as oral liquid formulations are required to contain
pediatric dosing information in their labeling.
Correct Ans - B. There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Why are Neonates at greater risk for toxicity with highly protein-bound drugs?
A. Protein binding is decreased in neonates increasing the amount of free drug
available.
B. The protein-bound drugs are not eliminated effectively in neonates.
C. Neonates are unable to metabolize these highly protein-bound drugs.
D. Protein binding is increased in neonates, making measurement of serum
levels of the drug inaccurate.
Correct Ans - A. Protein binding is decreased in neonates increasing the
amount of free drug available.
At what age are adult levels of renal function achieved? •
A. 6 months
B. 12 months
C. 24 months
D. 3 years old
Correct Ans - B. 12 months
What is the list that identifies drugs with a high likelihood of causing adverse
effects in the elderly?
, 2
A. No use list
B. Beers list
C. Pharmacists list
D. Adverse drug list
Correct Ans - B. Beers list
In pediatric patients gastric acidity does not reach adult values for
Correct Ans - 2 Years
The principles underlying complication to drug therapy in the elderly
include , , , and .
Correct Ans - altered pharmacokinetics, multiple and severe illnesses,
multiple-drug therapy, and poor adherence.
Altered absorption of drugs in the elderly may result in drug response
Correct Ans - Delay
The four major factors that can alter drug distribution in the elderly include _,
_, _, and _?
Correct Ans - increased body fat, decreased percentage of lean body mass,
decreased total body water, and reduced concentration of serum albumin.
The most important cause of adverse drug reactions in the elderly is .
Correct Ans - drug accumulation secondary to reduced renal excretion.
In the elderly, the proper index of renal function is .
Correct Ans - creatinine clearance or GFR
Name factors underlying the increase in adverse reactions in the geriatric
population:
Correct Ans - • Polypharmacy
• Severe illness,
• multiple pathologies,
• greater use of drugs that have a low therapeutic index
• Inadequate supervision
• Poor patient adherence
, lOMoAR cPSD| 57629747
messages.downloaded_by
lOMoAR cPSD| 57629747
NURS 5334 Adv. Pharmacotherapeutics, Final Review -
Lehne's Pharmacology End Of Module Review
Questions & Answers (M1-M4)
Why do many medications lack pediatric dosing information in their drug
labeling?
A. Most medications are not used in pediatric patients.
B. There is a lack of evidence-based literature on the safe and effective use of
medications in children.
C. The FDA does not allow pediatric dosing information in product labeling.
D. Only products available as oral liquid formulations are required to contain
pediatric dosing information in their labeling.
Correct Ans - B. There is a lack of evidence-based literature on the safe and
effective use of medications in children.
Why are Neonates at greater risk for toxicity with highly protein-bound drugs?
A. Protein binding is decreased in neonates increasing the amount of free drug
available.
B. The protein-bound drugs are not eliminated effectively in neonates.
C. Neonates are unable to metabolize these highly protein-bound drugs.
D. Protein binding is increased in neonates, making measurement of serum
levels of the drug inaccurate.
Correct Ans - A. Protein binding is decreased in neonates increasing the
amount of free drug available.
At what age are adult levels of renal function achieved? •
A. 6 months
B. 12 months
C. 24 months
D. 3 years old
Correct Ans - B. 12 months
What is the list that identifies drugs with a high likelihood of causing adverse
effects in the elderly?
, 2
A. No use list
B. Beers list
C. Pharmacists list
D. Adverse drug list
Correct Ans - B. Beers list
In pediatric patients gastric acidity does not reach adult values for
Correct Ans - 2 Years
The principles underlying complication to drug therapy in the elderly
include , , , and .
Correct Ans - altered pharmacokinetics, multiple and severe illnesses,
multiple-drug therapy, and poor adherence.
Altered absorption of drugs in the elderly may result in drug response
Correct Ans - Delay
The four major factors that can alter drug distribution in the elderly include _,
_, _, and _?
Correct Ans - increased body fat, decreased percentage of lean body mass,
decreased total body water, and reduced concentration of serum albumin.
The most important cause of adverse drug reactions in the elderly is .
Correct Ans - drug accumulation secondary to reduced renal excretion.
In the elderly, the proper index of renal function is .
Correct Ans - creatinine clearance or GFR
Name factors underlying the increase in adverse reactions in the geriatric
population:
Correct Ans - • Polypharmacy
• Severe illness,
• multiple pathologies,
• greater use of drugs that have a low therapeutic index
• Inadequate supervision
• Poor patient adherence
, lOMoAR cPSD| 57629747
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