Page 1 of 822
!x !x !x
TEST BANK !x
Katzung's Basic and Clinical Pharmacol
!x !x !x !x!x
ogy, 16th Edition
!x !x ! x
by Todd W. Vanderah, Chapters 1 - 66
!x !x !x !x !x !x !x ! x
Katzung's Basic and Clinical Pharmacology
!x !x !x !x
, Page 2 of 822 !x !x !x
Table of Contents !x !x
1. Introduction: The Nature of Drugs & Drug Development & Regulation
!x !x !x !x !x !x !x !x !x
2. Drug Receptors & Pharmacodynamics
!x !x !x
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
!x !x !x !x !x !x !x !x !x !x !x
4. Drug Biotransformation
!x
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
!x !x !x
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs !x !x !x
8. Cholinoceptor-Blocking Drugs !x
9. Adrenoceptor Agonists & Sympathomimetic Drugs
!x !x !x !x
10. Adrenoceptor Antagonist Drugs !x !x
11. Antihypertensive Agents !x
12. Vasodilators & the Treatment of Angina Pectoris
!x !x !x !x !x !x
13. Drugs Used in Heart Failure
!x !x !x !x
14. Agents Used in Cardiac Arrhythmias
!x !x !x !x
15. Diuretic Agents !x
16. Histamine, Serotonin, & the Ergot Alkaloids
!x !x !x !x !x
17. Vasoactive Peptides !x
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
!x !x !x !x !x !x !x
19. Nitric Oxide
!x
20. Drugs Used in Asthma
!x !x !x
21. Introduction to the Pharmacology of CNS Drugs
!x !x !x !x !x !x
22. Sedative-Hypnotic Drugs !x
23. The Alcohols
!x
24. Antiseizure Drugs !x
25. General Anesthetics !x
26. Local Anesthetics
!x
27. Skeletal Muscle Relaxants
!x !x
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
!x !x !x !x !x !x !x
29. Antipsychotic Agents & Lithium !x !x !x
30. Antidepressant Agents !x
31. Opioid Agonists & Antagonists
!x !x !x
32. Drugs of Abuse
!x !x
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
!x !x !x !x !x !x
34. Drugs Used in Disorders of Coagulation
!x !x !x !x !x
35. Agents Used in Dyslipidemia
!x !x !x
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
!x !x !x
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
!x !x !x !x !x !x !x !x !x
37. Hypothalamic & Pituitary Hormones !x !x !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
, Page 3 of 822 !x !x !x
38. Thyroid & Antithyroid Drugs
!x !x !x
39. Adrenocorticosteroids & Adrenocortical Antagonists !x !x !x
40. The Gonadal Hormones & Inhibitors
!x !x !x !x
41. Pancreatic Hormones & Antidiabetic Drugs
!x !x !x !x
42. Agents That Affect Bone Mineral Homeostasis
!x !x !x !x !x
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
!x !x !x !x !x !x !x
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
!x !x !x !x !x !x
45. Aminoglycosides & Spectinomycin !x !x
46. Sulfonamides, Trimethoprim, & Quinolones !x !x !x
47. Antimycobacterial Drugs !x
48. Antifungal Agents !x
49. Antiviral Agents !x
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
!x !x !x !x !x !x
51. Clinical Use of Antimicrobial Agents
!x !x !x !x
52. Antiprotozoal Drugs !x
53. Clinical Pharmacology of the Antihelminthic Drugs
!x !x !x !x !x
54. Cancer Chemotherapy
!x
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
!x !x !x !x !x
57. Heavy Metal Intoxication & Chelators
!x !x !x !x
58. Management of the Poisoned Patient !x !x !x !x
59. Special Aspects of Perinatal & Pediatric Pharmacology
!x !x !x !x !x !x
60. Special Aspects of Geriatric Pharmacology
!x !x !x !x
61. Dermatologic Pharmacology !x
62. Drugs Used in the Treatment of Gastrointestinal Diseases
!x !x !x !x !x !x !x
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
!x !x !x !x !x !x
64. Dietary Supplements & Herbal Medications
!x !x !x !x
65. Rational Prescribing & Prescription Writing
!x !x !x !x
66. Important Drug Interactions & Their Mechanisms
!x !x !x !x !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
, Page 4 of 822 !x !x !x
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
!x !x !x !x !x !x !x !x !x !x !x
1.
A nurse working in radiology administers iodine to a patient who is havin
!x !x !x !x !x !x !x !x !x !x !x !x
g a computed tomography (CT) scan. The nurse working on the oncology u
!x !x !x !x !x !x !x !x !x !x !x !x
nit administers chemotherapy to patients who have cancer. At the Public He
!x !x !x !x !x !x !x !x !x !x !x
alth Department, a nurse administers a measles-mumps-
!x !x !x !x !x !x
rubella (MMR) vaccine to a 14-month-!x !x !x !x !x
old child as a routine immunization. Which branch of pharmacology best de
!x !x !x !x !x !x !x !x !x !x !x
scribes the actions of all three nurses?
!x !x !x !x !x ! x
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are i
!x !x !x !x !x !x !x !x !x !x !x !x
nvolved with clinical pharmacology or pharmacotherapeutics, which is a br
!x !x !x !x !x !x !x !x !x
anch of pharmacology that deals with the uses of drugs to treat, prevent, an
!x !x !x !x !x !x !x !x !x !x !x !x !x
d diagnose disease. The radiology nurse is administering a drug to help diag
!x !x !x !x !x !x !x !x !x !x !x !x
nose a disease. The oncology nurse is administering a drug to help treat a dis
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
ease. Pharmacoeconomics includes any costs involved in drug therapy.
!x !x !x !x !x !x !x !x
Pharmacodynamics involves how a drug affects the body and pharmacokineti !x !x !x !x !x !x !x !x !x
cs is how the body acts on the body.
!x !x !x !x !x !x !x !x
2.
A physician has ordered intramuscular (IM) injections of morphine, a nar
!x !x !x !x !x !x !x !x !x !x
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. T
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
he nurse is aware this drug has a high abuse potential. Under what category
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
would morphine be classified? !x !x !x
A) Schedule I !x
B) Schedule II !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
!x !x !x
TEST BANK !x
Katzung's Basic and Clinical Pharmacol
!x !x !x !x!x
ogy, 16th Edition
!x !x ! x
by Todd W. Vanderah, Chapters 1 - 66
!x !x !x !x !x !x !x ! x
Katzung's Basic and Clinical Pharmacology
!x !x !x !x
, Page 2 of 822 !x !x !x
Table of Contents !x !x
1. Introduction: The Nature of Drugs & Drug Development & Regulation
!x !x !x !x !x !x !x !x !x
2. Drug Receptors & Pharmacodynamics
!x !x !x
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
!x !x !x !x !x !x !x !x !x !x !x
4. Drug Biotransformation
!x
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
!x !x !x
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs !x !x !x
8. Cholinoceptor-Blocking Drugs !x
9. Adrenoceptor Agonists & Sympathomimetic Drugs
!x !x !x !x
10. Adrenoceptor Antagonist Drugs !x !x
11. Antihypertensive Agents !x
12. Vasodilators & the Treatment of Angina Pectoris
!x !x !x !x !x !x
13. Drugs Used in Heart Failure
!x !x !x !x
14. Agents Used in Cardiac Arrhythmias
!x !x !x !x
15. Diuretic Agents !x
16. Histamine, Serotonin, & the Ergot Alkaloids
!x !x !x !x !x
17. Vasoactive Peptides !x
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
!x !x !x !x !x !x !x
19. Nitric Oxide
!x
20. Drugs Used in Asthma
!x !x !x
21. Introduction to the Pharmacology of CNS Drugs
!x !x !x !x !x !x
22. Sedative-Hypnotic Drugs !x
23. The Alcohols
!x
24. Antiseizure Drugs !x
25. General Anesthetics !x
26. Local Anesthetics
!x
27. Skeletal Muscle Relaxants
!x !x
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
!x !x !x !x !x !x !x
29. Antipsychotic Agents & Lithium !x !x !x
30. Antidepressant Agents !x
31. Opioid Agonists & Antagonists
!x !x !x
32. Drugs of Abuse
!x !x
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
!x !x !x !x !x !x
34. Drugs Used in Disorders of Coagulation
!x !x !x !x !x
35. Agents Used in Dyslipidemia
!x !x !x
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-
!x !x !x
Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
!x !x !x !x !x !x !x !x !x
37. Hypothalamic & Pituitary Hormones !x !x !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
, Page 3 of 822 !x !x !x
38. Thyroid & Antithyroid Drugs
!x !x !x
39. Adrenocorticosteroids & Adrenocortical Antagonists !x !x !x
40. The Gonadal Hormones & Inhibitors
!x !x !x !x
41. Pancreatic Hormones & Antidiabetic Drugs
!x !x !x !x
42. Agents That Affect Bone Mineral Homeostasis
!x !x !x !x !x
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
!x !x !x !x !x !x !x
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
!x !x !x !x !x !x
45. Aminoglycosides & Spectinomycin !x !x
46. Sulfonamides, Trimethoprim, & Quinolones !x !x !x
47. Antimycobacterial Drugs !x
48. Antifungal Agents !x
49. Antiviral Agents !x
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
!x !x !x !x !x !x
51. Clinical Use of Antimicrobial Agents
!x !x !x !x
52. Antiprotozoal Drugs !x
53. Clinical Pharmacology of the Antihelminthic Drugs
!x !x !x !x !x
54. Cancer Chemotherapy
!x
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
!x !x !x !x !x
57. Heavy Metal Intoxication & Chelators
!x !x !x !x
58. Management of the Poisoned Patient !x !x !x !x
59. Special Aspects of Perinatal & Pediatric Pharmacology
!x !x !x !x !x !x
60. Special Aspects of Geriatric Pharmacology
!x !x !x !x
61. Dermatologic Pharmacology !x
62. Drugs Used in the Treatment of Gastrointestinal Diseases
!x !x !x !x !x !x !x
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
!x !x !x !x !x !x
64. Dietary Supplements & Herbal Medications
!x !x !x !x
65. Rational Prescribing & Prescription Writing
!x !x !x !x
66. Important Drug Interactions & Their Mechanisms
!x !x !x !x !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
, Page 4 of 822 !x !x !x
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
!x !x !x !x !x !x !x !x !x !x !x
1.
A nurse working in radiology administers iodine to a patient who is havin
!x !x !x !x !x !x !x !x !x !x !x !x
g a computed tomography (CT) scan. The nurse working on the oncology u
!x !x !x !x !x !x !x !x !x !x !x !x
nit administers chemotherapy to patients who have cancer. At the Public He
!x !x !x !x !x !x !x !x !x !x !x
alth Department, a nurse administers a measles-mumps-
!x !x !x !x !x !x
rubella (MMR) vaccine to a 14-month-!x !x !x !x !x
old child as a routine immunization. Which branch of pharmacology best de
!x !x !x !x !x !x !x !x !x !x !x
scribes the actions of all three nurses?
!x !x !x !x !x ! x
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are i
!x !x !x !x !x !x !x !x !x !x !x !x
nvolved with clinical pharmacology or pharmacotherapeutics, which is a br
!x !x !x !x !x !x !x !x !x
anch of pharmacology that deals with the uses of drugs to treat, prevent, an
!x !x !x !x !x !x !x !x !x !x !x !x !x
d diagnose disease. The radiology nurse is administering a drug to help diag
!x !x !x !x !x !x !x !x !x !x !x !x
nose a disease. The oncology nurse is administering a drug to help treat a dis
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
ease. Pharmacoeconomics includes any costs involved in drug therapy.
!x !x !x !x !x !x !x !x
Pharmacodynamics involves how a drug affects the body and pharmacokineti !x !x !x !x !x !x !x !x !x
cs is how the body acts on the body.
!x !x !x !x !x !x !x !x
2.
A physician has ordered intramuscular (IM) injections of morphine, a nar
!x !x !x !x !x !x !x !x !x !x
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. T
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
he nurse is aware this drug has a high abuse potential. Under what category
!x !x !x !x !x !x !x !x !x !x !x !x !x !x
would morphine be classified? !x !x !x
A) Schedule I !x
B) Schedule II !x
Katzung's Basic and Clinical Pharmacology !x !x !x !x
