ONS ACTUAL PRACTICE EXAM QUESTIONS 2026-
2027 COMPLETE ACCURATE EXAM REAL
QUESTIONS AND CORRECT DETAILED ANSWERS
WITH RATIONALES (RELIABLE SOLUTIONS)
CURRENTLY UPDATED VERSION 2026 EDITION
A premenopausal patient with metastatic breast cancer is receiving
letrozole. Which other medication is also expected to be prescribed for
ovarian ablation?
a. degarelix
b. exemestane
c. goserelin
d. tamoxifen
c. goserelin
Concomitant ovarian ablation with a luteinizing hormone-releasing
hormone agonist therapy, such as goserelin, is recommended in the
adjuvant, recurrent, or metastatic settings for women with breast cancer
who are premenopausal.
A patient with an insulinoma would be most likely to experience which of
the following signs and symptoms?
a. hypoK, aclorhydria, vasoconstriction
b. glucose interolerance, diarrhea, anemia
c. abd pain, reflux, vit b6 deficiency
d. hypoglycemia, confusion, vision changes
d. hypoglycemia, confusion, vision changes
,A patient with esophageal cancer reports cramping and diarrhea after
eating meals. What should the nurse recommend?
a. chewing thoroughly
b. drinking at least 20oz of water during meals
c. decreasing dietary protein intake
d. eating small, freqeunt meals
d. eating small, freqeunt meals aka prevent dumping syndrome
What is the absolute neutrophil count for a patient who has a white
blood cell count of 500/mm3 with 32% polysegmented neutrophils and
7% bands?
a. 100/mm3
b. 125/mm3
c. 195/mm3
d. 223/mm3
c. 195/mm3
The absolute neutrophil count can be calculated by adding
polysegmented neutrophils and bands, converting to a percentage, and
multiplying by the white blood cell count (0.32 +0.07 = 0.39) x 500 =
195/mm3.
6. A patient with cancer receiving palliative services reports poor sleep,
fatigue, and frequently feeling worried. Which medication should the
nurse expect to be prescribed for the patient?
a. miratazapine
b. diphenhydramine
c. citalopram
d. methylphenidate
c. citalopram
The symptoms described are consistent with generalized anxiety.
Selective serotonin reuptake inhibitors, such as citalopram, are
considered first-line for the management of generalized anxiety disorder.
, 7. The nurse is assessing a patient with an ileostomy. The peristomal skin is
erythematous, excoriated, and bleeding. Which of the following
complications should the nurse first suspect?
a. stenosis requiring revision
b. improper pouch fit
c. increased output over baseline
d. allergy to device
b. improper pouch fit
8. Which of these factors is most likely to result in a higher incidence of
acute graft-versus- host disease?
a. female to male donation
b. HLA identical related donors
c. reduced intensity conditioning regimen
d. T cell depleted grafts
a. female to male donation
A male recipient receiving the stem cells of a female increases the risk for
the development of acute graft-versus-host disease.
9. A patient with cancer has a new onset of confusion, acute nausea, and
blurred vision. The nurse anticipates the physician to order which
diagnostic test?
a. U/S of gallblader & bile ducts
b. CXR
c. Skeletal scintigraphy
d. MRI of brain
d. MRI of brain
2027 COMPLETE ACCURATE EXAM REAL
QUESTIONS AND CORRECT DETAILED ANSWERS
WITH RATIONALES (RELIABLE SOLUTIONS)
CURRENTLY UPDATED VERSION 2026 EDITION
A premenopausal patient with metastatic breast cancer is receiving
letrozole. Which other medication is also expected to be prescribed for
ovarian ablation?
a. degarelix
b. exemestane
c. goserelin
d. tamoxifen
c. goserelin
Concomitant ovarian ablation with a luteinizing hormone-releasing
hormone agonist therapy, such as goserelin, is recommended in the
adjuvant, recurrent, or metastatic settings for women with breast cancer
who are premenopausal.
A patient with an insulinoma would be most likely to experience which of
the following signs and symptoms?
a. hypoK, aclorhydria, vasoconstriction
b. glucose interolerance, diarrhea, anemia
c. abd pain, reflux, vit b6 deficiency
d. hypoglycemia, confusion, vision changes
d. hypoglycemia, confusion, vision changes
,A patient with esophageal cancer reports cramping and diarrhea after
eating meals. What should the nurse recommend?
a. chewing thoroughly
b. drinking at least 20oz of water during meals
c. decreasing dietary protein intake
d. eating small, freqeunt meals
d. eating small, freqeunt meals aka prevent dumping syndrome
What is the absolute neutrophil count for a patient who has a white
blood cell count of 500/mm3 with 32% polysegmented neutrophils and
7% bands?
a. 100/mm3
b. 125/mm3
c. 195/mm3
d. 223/mm3
c. 195/mm3
The absolute neutrophil count can be calculated by adding
polysegmented neutrophils and bands, converting to a percentage, and
multiplying by the white blood cell count (0.32 +0.07 = 0.39) x 500 =
195/mm3.
6. A patient with cancer receiving palliative services reports poor sleep,
fatigue, and frequently feeling worried. Which medication should the
nurse expect to be prescribed for the patient?
a. miratazapine
b. diphenhydramine
c. citalopram
d. methylphenidate
c. citalopram
The symptoms described are consistent with generalized anxiety.
Selective serotonin reuptake inhibitors, such as citalopram, are
considered first-line for the management of generalized anxiety disorder.
, 7. The nurse is assessing a patient with an ileostomy. The peristomal skin is
erythematous, excoriated, and bleeding. Which of the following
complications should the nurse first suspect?
a. stenosis requiring revision
b. improper pouch fit
c. increased output over baseline
d. allergy to device
b. improper pouch fit
8. Which of these factors is most likely to result in a higher incidence of
acute graft-versus- host disease?
a. female to male donation
b. HLA identical related donors
c. reduced intensity conditioning regimen
d. T cell depleted grafts
a. female to male donation
A male recipient receiving the stem cells of a female increases the risk for
the development of acute graft-versus-host disease.
9. A patient with cancer has a new onset of confusion, acute nausea, and
blurred vision. The nurse anticipates the physician to order which
diagnostic test?
a. U/S of gallblader & bile ducts
b. CXR
c. Skeletal scintigraphy
d. MRI of brain
d. MRI of brain
