ACTUAL QUESTIONS AND CORRECT
ANSWERS
What is psychopharmacology? - correct answer the study of how drugs affect the nervous
system and behavior
What does exogenous mean? - correct answer originating from outside the body
What is the role of the blood-brain barrier? - correct answer it limits which substances can
enter the brain from the bloodstream, protecting neural tissue
Name some routes of drug administration - correct answer oral, inhalation, intravenous (iv),
intramuscular, topical
Which drug route acts fastest? - correct answer intravenous (iv) injection delivers drugs rapidly
to the brain
Which route acts slowest? - correct answer oral administration, because it must pass through
the digestive system
What happens with repeated drug administration? - correct answer tolerance develops (less
effect) or sensitization (greater effect)
What is a drug tolerance? - correct answer decreased sensitivity to a drug after repeated use
What is sensitization? - correct answer increase response to a drug after repeated exposure
What is an agonist? - correct answer a drug that mimics or enhances the effects of a
neurotransmitter
, What is an antagonist? - correct answer a drug that blocks or reduces the effects of a
neurotransmitter
How can drugs affect synaptic activity presynaptically? - correct answer they can affect
neurotransmitter synthesis, storage, release, or reuptake
How can drugs affect synaptic activity postsynaptically? - correct answer they can mimic or
block receptor activation, or alter receptor sensitivity
What does acetylcholine (ach) do? - correct answer controls muscle movement and memory;
linked to attention and learning
What are ach receptors? - correct answer nicotinic (ionotropic) and muscarinic (metabotropic)
What drug affects ach - correct answer nicotine activates nicotinic receptors
What is dopamine (da) involved in? - correct answer movement, motivation, reward, and
learning
What drugs affect dopamine? - correct answer cocaine and amphetamines increase dopamine
levels
What is norepinephrine (ne) responsible for> - correct answer arousal, alertness, mood, and
stress responses
What is serotonin (5-ht) involved in? - correct answer mood, sleep, appetite, and anxiety
What drug affect serotonin? - correct answer ssris (e.g., prozac) block serotonin reuptake,
increasing its effects
What is glutamate? - correct answer the main excitatory neurotransmitters in the brain