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vesicants ✔Correct Answer-bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin,
etposide, idarubicin, melphalan, taxol, vincristine
cisplatin antidote ✔Correct Answer-sodium thiosulfate
doxorubicin antidote ✔Correct Answer-Dexrazoxane
vincristine antidote ✔Correct Answer-hyaluronidase
Alkylating agents ✔Correct Answer-busulfan, cytoxan, melphalan, ifosfamide, carmustine; cell
cycle non-specific; affects heme, GI, reproductive
antimetabolites ✔Correct Answer-methotrexate, 5-FU, cytarabine, gemcitabine, fludarabine;
cell cycle specific, affect counts & GI
platinum compounds ✔Correct Answer-cisplatin, carboplatin, oxaliplatin; cell cycle non-
specific; affects heme, GI, neuro, and urinary
topoisomerase targeting agents ✔Correct Answer-ironitecan, anthracyclines (daunorubicin,
doxorubicin, idarubicin)
Microtubule targeting agents ✔Correct Answer-vincristine, taxanes (paclitaxel and docetaxel);
cell-cycle specific, affects heme, skin, neuro, reproductive
Chemos likely to cause nausea ✔Correct Answer-carboplatin, carmustine, cisplatin, cytoxan,
cytarabine, doxorubicin, melphalan, MTX
Chemo likely to cause alopecia ✔Correct Answer-cytoxan, daunorubicin, doxorubicin,
docetaxel, etoposide, idarubicine, ifosfamide, paclitaxel
bleomycin ✔Correct Answer-VESICANT, risk for anaphylaxis (need test dose, emergency meds
at bedside), risk for pulmonary fibrosis and interstitial pneumonitis
busulfan ✔Correct Answer-dosing based on blood busulfan levels, dilantin given to prevent
seizures, no tylenol during or 48 hrs after
carboplatin ✔Correct Answer-check creatinin, renal and ototoxic
carmustine ✔Correct Answer-VESICANT, monitor for dizziness and severe nausea