ONS Chemotherapy Immunotherapy Certificate Exam
with all Correct & 100% Verified Answers |Latest Version
|Already Graded A+
Define neoadjuvant therapy ✔Correct Answer-Treatment is given prior to surgery to shrink
the tumor
Define adjuvant therapy ✔Correct Answer-Additional cancer treatment given after the
primary treatment to lower the risk that the cancer reoccur
3 subcategories of alkylating agents: ✔Correct Answer-1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as
they work similarly)
3. Nitrosoureas
Common alkylating agents: ✔Correct Answer-Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: ✔Correct Answer-Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? ✔Correct Answer-Able to cross the blood-brain
barrier; can be effective in treating some brain tumors
Common nitrosoureas agents: ✔Correct Answer-Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: ✔Correct Answer-Carboplatin
These agents are typically categorized as highly emetogenic: ✔Correct Answer-1. Alkylating
agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas: ✔Correct Answer-BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? ✔Correct Answer-Bladder protectant with
administration of cyclophosphamide or ifosfamide
, Instruct pts receiving ________ to avoid exposure to cold air and consuming cold fluids for 3-4
days following treatment ✔Correct Answer-Oxaliplatin
How do antimetabolites function? ✔Correct Answer-By blocking DNA and RNA growth by
interfering with enzymes needed for normal cell metabolism
Antimetabolites work in the ___ phase. ✔Correct Answer-S
Common side effects of antimetabolites: ✔Correct Answer-Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: ✔Correct Answer-Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of administration for
vincristine? ✔Correct Answer-IV piggyback via gravity
Anthracycline antitumor abx work by: ✔Correct Answer-Interfering with enzymes necessary
for DNA to replicate in ALL phases of the cell cycle
The two major classifications of antitumor antibiotics are: ✔Correct Answer-Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: ✔Correct Answer-Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has anthracycline-type properties.
✔Correct Answer-Mitoxantrone
Common non-anthracycline antitumor abx: ✔Correct Answer-Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: ✔Correct Answer-Vesicant --> extravasation
Cardiac function
with all Correct & 100% Verified Answers |Latest Version
|Already Graded A+
Define neoadjuvant therapy ✔Correct Answer-Treatment is given prior to surgery to shrink
the tumor
Define adjuvant therapy ✔Correct Answer-Additional cancer treatment given after the
primary treatment to lower the risk that the cancer reoccur
3 subcategories of alkylating agents: ✔Correct Answer-1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as
they work similarly)
3. Nitrosoureas
Common alkylating agents: ✔Correct Answer-Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: ✔Correct Answer-Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? ✔Correct Answer-Able to cross the blood-brain
barrier; can be effective in treating some brain tumors
Common nitrosoureas agents: ✔Correct Answer-Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: ✔Correct Answer-Carboplatin
These agents are typically categorized as highly emetogenic: ✔Correct Answer-1. Alkylating
agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas: ✔Correct Answer-BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? ✔Correct Answer-Bladder protectant with
administration of cyclophosphamide or ifosfamide
, Instruct pts receiving ________ to avoid exposure to cold air and consuming cold fluids for 3-4
days following treatment ✔Correct Answer-Oxaliplatin
How do antimetabolites function? ✔Correct Answer-By blocking DNA and RNA growth by
interfering with enzymes needed for normal cell metabolism
Antimetabolites work in the ___ phase. ✔Correct Answer-S
Common side effects of antimetabolites: ✔Correct Answer-Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: ✔Correct Answer-Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of administration for
vincristine? ✔Correct Answer-IV piggyback via gravity
Anthracycline antitumor abx work by: ✔Correct Answer-Interfering with enzymes necessary
for DNA to replicate in ALL phases of the cell cycle
The two major classifications of antitumor antibiotics are: ✔Correct Answer-Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: ✔Correct Answer-Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has anthracycline-type properties.
✔Correct Answer-Mitoxantrone
Common non-anthracycline antitumor abx: ✔Correct Answer-Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: ✔Correct Answer-Vesicant --> extravasation
Cardiac function
