WCU PATHOPHYSIOLOGY 370 EXAM NEWEST 2026
PACKAGE DEAL| 2 LATEST VERSION WITH COMPLETE
550 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+| WCU PATHOPHYSIOLOGY 370 FINAL
EXAM PREP|| BRAND NEW!!
1. A 68-year-old patient with long-standing hypertension
presents with echocardiogram findings showing thickened left
ventricular myocardium. This cellular adaptation is best
described as:
A) Hyperplasia
B) Metaplasia
C) Hypertrophy
D) Dysplasia
1
,Correct Answer: C
Rationale: Hypertrophy is an increase in cell size leading to organ
enlargement. The heart responds to increased workload (pressure
overload from hypertension) by enlarging individual myocytes
(increased protein synthesis) without increasing cell number, as
cardiac myocytes have limited replicative capacity .
2. A female patient develops a goiter due to iodine deficiency.
The thyroid enlargement results from which cellular
adaptation?
A) Atrophy
B) Hypertrophy
C) Hyperplasia
D) Metaplasia
Correct Answer: C
Rationale: Hyperplasia is an increase in cell number. Iodine
2
,deficiency leads to decreased thyroid hormone production, causing
increased TSH secretion, which stimulates proliferation of thyroid
follicular cells, resulting in gland enlargement (goiter) .
3. A chronic smoker develops a persistent cough. Bronchial
biopsy reveals replacement of normal ciliated columnar
epithelium with stratified squamous epithelium. This change
is called:
A) Dysplasia
B) Anaplasia
C) Hyperplasia
D) Metaplasia
Correct Answer: D
Rationale: Metaplasia is a reversible change in which one
differentiated cell type is replaced by another (usually less
specialized) cell type. In smokers, chronic irritation causes ciliated
3
, columnar epithelium to convert to more protective stratified
squamous epithelium—but ciliary function is lost, leading to
impaired mucus clearance .
4. A patient with chronic gastroesophageal reflux disease
(GERD) undergoes endoscopy. Biopsy of the distal esophagus
shows replacement of squamous epithelium with columnar
epithelium containing goblet cells. This condition is called:
A) Barrett's esophagus
B) Esophageal metaplasia
C) Esophageal dysplasia
D) Esophageal hyperplasia
Correct Answer: A
Rationale: Barrett's esophagus is a specific type of metaplasia
where the normal stratified squamous epithelium of the distal
esophagus is replaced by specialized intestinal-type columnar
4
PACKAGE DEAL| 2 LATEST VERSION WITH COMPLETE
550 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) ALREADY
GRADED A+| WCU PATHOPHYSIOLOGY 370 FINAL
EXAM PREP|| BRAND NEW!!
1. A 68-year-old patient with long-standing hypertension
presents with echocardiogram findings showing thickened left
ventricular myocardium. This cellular adaptation is best
described as:
A) Hyperplasia
B) Metaplasia
C) Hypertrophy
D) Dysplasia
1
,Correct Answer: C
Rationale: Hypertrophy is an increase in cell size leading to organ
enlargement. The heart responds to increased workload (pressure
overload from hypertension) by enlarging individual myocytes
(increased protein synthesis) without increasing cell number, as
cardiac myocytes have limited replicative capacity .
2. A female patient develops a goiter due to iodine deficiency.
The thyroid enlargement results from which cellular
adaptation?
A) Atrophy
B) Hypertrophy
C) Hyperplasia
D) Metaplasia
Correct Answer: C
Rationale: Hyperplasia is an increase in cell number. Iodine
2
,deficiency leads to decreased thyroid hormone production, causing
increased TSH secretion, which stimulates proliferation of thyroid
follicular cells, resulting in gland enlargement (goiter) .
3. A chronic smoker develops a persistent cough. Bronchial
biopsy reveals replacement of normal ciliated columnar
epithelium with stratified squamous epithelium. This change
is called:
A) Dysplasia
B) Anaplasia
C) Hyperplasia
D) Metaplasia
Correct Answer: D
Rationale: Metaplasia is a reversible change in which one
differentiated cell type is replaced by another (usually less
specialized) cell type. In smokers, chronic irritation causes ciliated
3
, columnar epithelium to convert to more protective stratified
squamous epithelium—but ciliary function is lost, leading to
impaired mucus clearance .
4. A patient with chronic gastroesophageal reflux disease
(GERD) undergoes endoscopy. Biopsy of the distal esophagus
shows replacement of squamous epithelium with columnar
epithelium containing goblet cells. This condition is called:
A) Barrett's esophagus
B) Esophageal metaplasia
C) Esophageal dysplasia
D) Esophageal hyperplasia
Correct Answer: A
Rationale: Barrett's esophagus is a specific type of metaplasia
where the normal stratified squamous epithelium of the distal
esophagus is replaced by specialized intestinal-type columnar
4
