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ANCC FAMILY NURSE PRACTITIONER (FNP) CERTIFICATION EXAM 200-QUESTION PRACTICE BANK WITH CORRECT VERIFIED ANSWERS, DETAILED CLINICAL RATIONALES, AND COMPREHENSIVE COVERAGE OF ALL CORE TEST DOMAINS (HEALTH PROMOTION, ASSESSMENT, DIFFERENTIAL DIAGNOSIS, PHAR

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ANCC FAMILY NURSE PRACTITIONER (FNP) CERTIFICATION EXAM 200-QUESTION PRACTICE BANK WITH CORRECT VERIFIED ANSWERS, DETAILED CLINICAL RATIONALES, AND COMPREHENSIVE COVERAGE OF ALL CORE TEST DOMAINS (HEALTH PROMOTION, ASSESSMENT, DIFFERENTIAL DIAGNOSIS, PHARMACOLOGY, AND CHRONIC DISEASE MANAGEMENT) — ALREADY GRADED A+ / HIGH-YIELD BOARD REVIEW 1. A 72-year-old male presents with complaints of progressive difficulty walking and urinary incontinence. On examination, you note a shuffling gait, postural instability, and resting tremor. Which of the following is the most likely diagnosis? A) Alzheimer's disease B) Parkinson's disease C) Huntington's disease D) Amyotrophic lateral sclerosis Correct Answer: B - Parkinson's disease is characterized by the classic triad of resting tremor, rigidity, and bradykinesia, along with postural instability and gait disturbances. Urinary incontinence can occur in later stages. Alzheimer's typically presents with cognitive decline without these motor findings. Huntington's presents with chorea. ALS presents with both upper and lower motor neuron signs. 2. A 45-year-old woman presents with fatigue, weight gain, cold intolerance, and constipation. Her TSH is elevated and free T4 is low. Which of the following is the most appropriate initial treatment? A) Levothyroxine B) Methimazole C) Radioactive iodine ablation D) Thyroidectomy Correct Answer: A - This patient has primary hypothyroidism, as evidenced by elevated TSH and low free T4. The standard treatment is levothyroxine replacement therapy. Methimazole and radioactive iodine are used for hyperthyroidism. Thyroidectomy is reserved for specific cases such as thyroid cancer or large goiters causing compressive symptoms. 3. A 6-month-old infant is brought in for a well-child visit. Which of the following immunizations is recommended at this age? A) Hepatitis B B) DTaP, IPV, Hib, PCV13, RV C) MMR, Varicella D) Tdap, MenACWY Correct Answer: B - At 6 months of age, the CDC recommends DTaP, IPV, Hib, PCV13, and RV. Hepatitis B is given at birth and 1-2 months. MMR and Varicella are given at 12-15 months. Tdap and MenACWY are given at 11-12 years. 4. A 55-year-old male with a history of hypertension presents with acute onset of severe chest pain radiating to his back. His blood pressure is 160/100 mmHg in the right arm and 90/60 mmHg in the left arm. Which of the following is the most likely diagnosis? A) Myocardial infarction B) Pulmonary embolism C) Aortic dissection D) Pericarditis Correct Answer: C - Aortic dissection should be suspected in a patient with acute severe chest pain radiating to the back with a differential in blood pressure between arms. Myocardial infarction typically presents with chest pressure and EKG changes. Pulmonary embolism presents with sudden dyspnea and hypoxia. Pericarditis pain is often positional and relieved by leaning forward. 5. A 28-year-old woman reports a 3-week history of depressed mood, anhedonia, fatigue, and difficulty concentrating. She denies suicidal ideation. Which of the following is the most appropriate initial step? A) Prescribe an SSRI B) Refer to psychiatry C) Conduct a thorough biopsychosocial assessment and screen for substance use D) Order thyroid function tests Correct Answer: C - A thorough assessment, including screening for substance use, is essential before initiating treatment. While SSRIs may be appropriate, a comprehensive evaluation is the first step. Thyroid function tests may be indicated but are not the initial step. Referral to psychiatry may be needed if severe or if there is no response to initial treatment. 6. A 60-year-old woman with a history of type 2 diabetes presents with a non-healing ulcer on her right foot. The ulcer is surrounded by erythema and there is purulent drainage. Which of the following is the most appropriate next step? A) Prescribe oral antibiotics B) Obtain a wound culture and start empiric antibiotics C) Debride the wound and refer to a wound care specialist D) Obtain an X-ray of the foot to rule out osteomyelitis Correct Answer: D - In a diabetic patient with a non-healing ulcer and signs of infection, osteomyelitis must be ruled out. An X-ray can reveal bone involvement. While antibiotics and debridement are important, imaging to assess for osteomyelitis is a priority. A wound culture can guide antibiotic selection. 7. A 16-year-old adolescent is being seen for a sports physical. He reports no significant medical history. Which of the following screening tests is recommended for this age group? A) Lipid panel B) Hemoglobin A1c C) Depression screening D) Bone density scan Correct Answer: C - The USPSTF recommends screening for depression in adolescents aged 12-18 years. Lipid screening is recommended for those with risk factors. Hemoglobin A1c is not routinely recommended for all adolescents. Bone density scans are not indicated in this age group. 8. A 35-year-old pregnant woman at 28 weeks gestation presents with new-onset hypertension and proteinuria. Which of the following is the most likely diagnosis? A) Gestational hypertension B) Preeclampsia C) Chronic hypertension D) Eclampsia Correct Answer: B - Preeclampsia is defined as new-onset hypertension after 20 weeks of gestation with proteinuria or other signs of end-organ dysfunction. Gestational hypertension is hypertension without proteinuria. Chronic hypertension is pre-existing hypertension. Eclampsia is preeclampsia with seizures. 9. A 70-year-old male with a history of COPD presents with worsening dyspnea, increased sputum production, and fever. Which of the following findings on chest X-ray would be most consistent with an acute exacerbation of COPD? A) Hyperinflation B) Infiltrate C) Pleural effusion D) Pneumothorax Correct Answer: B - An infiltrate on chest X-ray suggests an infectious etiology, which is a common cause of COPD exacerbations. Hyperinflation is a chronic finding in COPD. Pleural effusion and pneumothorax are less common causes of acute exacerbation. 10. A 5-year-old child presents with a 2-day history of fever, cough, and runny nose. On examination, you note small, red spots with white centers on the buccal mucosa. Which of the following is the most likely diagnosis? A) Scarlet fever B) Measles C) Rubella D) Fifth disease Correct Answer: B - Koplik spots (small, red spots with white centers on the buccal mucosa) are pathognomonic for measles. Scarlet fever presents with a sandpaper-like rash. Rubella presents with a maculopapular rash and lymphadenopathy. Fifth disease presents with a "slapped cheek" rash.

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ANCC FAMILY NURSE PRACTITIONER CERTIFICATION
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ANCC FAMILY NURSE PRACTITIONER CERTIFICATION

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ANCC FAMILY NURSE PRACTITIONER (FNP) CERTIFICATION
EXAM 200-QUESTION PRACTICE BANK WITH CORRECT
VERIFIED ANSWERS, DETAILED CLINICAL RATIONALES, AND
COMPREHENSIVE COVERAGE OF ALL CORE TEST DOMAINS
(HEALTH PROMOTION, ASSESSMENT, DIFFERENTIAL
DIAGNOSIS, PHARMACOLOGY, AND CHRONIC DISEASE
MANAGEMENT) — ALREADY GRADED A+ / HIGH-YIELD BOARD
REVIEW




1. A 72-year-old male presents with complaints of progressive
difficulty walking and urinary incontinence. On examination, you note
a shuffling gait, postural instability, and resting tremor. Which of the
following is the most likely diagnosis?
A) Alzheimer's disease
B) Parkinson's disease
C) Huntington's disease
D) Amyotrophic lateral sclerosis
Correct Answer: B - Parkinson's disease is characterized by the classic
triad of resting tremor, rigidity, and bradykinesia, along with postural
instability and gait disturbances. Urinary incontinence can occur in later
stages. Alzheimer's typically presents with cognitive decline without
these motor findings. Huntington's presents with chorea. ALS presents
with both upper and lower motor neuron signs.
2. A 45-year-old woman presents with fatigue, weight gain, cold
intolerance, and constipation. Her TSH is elevated and free T4 is low.

,Which of the following is the most appropriate initial treatment?
A) Levothyroxine
B) Methimazole
C) Radioactive iodine ablation
D) Thyroidectomy
Correct Answer: A - This patient has primary hypothyroidism, as
evidenced by elevated TSH and low free T4. The standard treatment is
levothyroxine replacement therapy. Methimazole and radioactive iodine
are used for hyperthyroidism. Thyroidectomy is reserved for specific
cases such as thyroid cancer or large goiters causing compressive
symptoms.
3. A 6-month-old infant is brought in for a well-child visit. Which of
the following immunizations is recommended at this age?
A) Hepatitis B
B) DTaP, IPV, Hib, PCV13, RV
C) MMR, Varicella
D) Tdap, MenACWY
Correct Answer: B - At 6 months of age, the CDC recommends DTaP, IPV,
Hib, PCV13, and RV. Hepatitis B is given at birth and 1-2 months. MMR
and Varicella are given at 12-15 months. Tdap and MenACWY are given
at 11-12 years.
4. A 55-year-old male with a history of hypertension presents with
acute onset of severe chest pain radiating to his back. His blood
pressure is 160/100 mmHg in the right arm and 90/60 mmHg in the
left arm. Which of the following is the most likely diagnosis?
A) Myocardial infarction
B) Pulmonary embolism
C) Aortic dissection

,D) Pericarditis
Correct Answer: C - Aortic dissection should be suspected in a patient
with acute severe chest pain radiating to the back with a differential in
blood pressure between arms. Myocardial infarction typically presents
with chest pressure and EKG changes. Pulmonary embolism presents
with sudden dyspnea and hypoxia. Pericarditis pain is often positional
and relieved by leaning forward.
5. A 28-year-old woman reports a 3-week history of depressed mood,
anhedonia, fatigue, and difficulty concentrating. She denies suicidal
ideation. Which of the following is the most appropriate initial step?
A) Prescribe an SSRI
B) Refer to psychiatry
C) Conduct a thorough biopsychosocial assessment and screen for
substance use
D) Order thyroid function tests
Correct Answer: C - A thorough assessment, including screening for
substance use, is essential before initiating treatment. While SSRIs may
be appropriate, a comprehensive evaluation is the first step. Thyroid
function tests may be indicated but are not the initial step. Referral to
psychiatry may be needed if severe or if there is no response to initial
treatment.
6. A 60-year-old woman with a history of type 2 diabetes presents
with a non-healing ulcer on her right foot. The ulcer is surrounded by
erythema and there is purulent drainage. Which of the following is the
most appropriate next step?
A) Prescribe oral antibiotics
B) Obtain a wound culture and start empiric antibiotics
C) Debride the wound and refer to a wound care specialist

, D) Obtain an X-ray of the foot to rule out osteomyelitis
Correct Answer: D - In a diabetic patient with a non-healing ulcer and
signs of infection, osteomyelitis must be ruled out. An X-ray can reveal
bone involvement. While antibiotics and debridement are important,
imaging to assess for osteomyelitis is a priority. A wound culture can
guide antibiotic selection.
7. A 16-year-old adolescent is being seen for a sports physical. He
reports no significant medical history. Which of the following
screening tests is recommended for this age group?
A) Lipid panel
B) Hemoglobin A1c
C) Depression screening
D) Bone density scan
Correct Answer: C - The USPSTF recommends screening for depression
in adolescents aged 12-18 years. Lipid screening is recommended for
those with risk factors. Hemoglobin A1c is not routinely recommended
for all adolescents. Bone density scans are not indicated in this age
group.
8. A 35-year-old pregnant woman at 28 weeks gestation presents with
new-onset hypertension and proteinuria. Which of the following is the
most likely diagnosis?
A) Gestational hypertension
B) Preeclampsia
C) Chronic hypertension
D) Eclampsia
Correct Answer: B - Preeclampsia is defined as new-onset hypertension
after 20 weeks of gestation with proteinuria or other signs of end-organ
dysfunction. Gestational hypertension is hypertension without

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ANCC FAMILY NURSE PRACTITIONER CERTIFICATION

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