ATI PN Pharmacology (Pharm) Proctored
Exam 2026–2027 | Complete 250 Practice
Questions with Detailed Answer Rationales |
Comprehensive Practical Nursing Study
Guide
A client is taking Humulin NPH insulin daily every morning. The nurse reinforces
instructions for the client and tells the client that the most likely time for a hypoglycemic
reaction to occur is: - Correct Answer - 4 to 12 hours after administration
A client with diabetes mellitus visits a health care clinic. The client's diabetes mellitus
previously had been well controlled with glyburide (DiaBeta) daily, but recently the
fasting blood glucose level has been 180 to 200 mg/dL. Which medication, if added to
the client's regimen, may have contributed to the hyperglycemia? - Correct Answer -
Prednisone
A community health nurse visits a client at home. Prednisone 10 mg orally daily has
been prescribed for the client and the nurse reinforces teaching for the client about the
medication. Which statement, if made by the client, indicates that further teaching is
necessary? - Correct Answer - "I can take aspirin or my antihistamine if I need it."
Desmopressin acetate (DDAVP) is prescribed for the treatment of diabetes insipidus.
The nurse monitors the client after medication administration for which therapeutic
response? - Correct Answer - Decreased urinary output
A client with Crohn's disease is scheduled to receive an infusion of infliximab
(Remicade). The nurse assisting in caring for the client should take which action to
monitor the effectiveness of treatment? - Correct Answer - Checking the frequency and
consistency of bowel movements
pg. 1
,The home health care nurse is visiting a client who was recently diagnosed with type 2
diabetes mellitus. The client is prescribed repaglinide (Prandin) and metformin
(Glucophage) and asks the nurse to explain these medications. The nurse should
reinforce which instructions to the client? Select all that apply. - Correct Answer - 1.
Diarrhea can occur secondary to the metformin.
2. The repaglinide is not taken if a meal is skipped.
3. The repaglinide is taken 30 minutes before eating.
4. Candy or another simple sugar is carried and used to treat mild hypoglycemia
episodes.
The client has a PRN prescription for loperamide hydrochloride (Imodium). The nurse
understands that this medication is used for which condition? - Correct Answer - An
episode of diarrhea
The client has a PRN prescription for ondansetron (Zofran). For which condition should
this medication be administered to the postoperative client? - Correct Answer - Nausea
and vomiting
The client has begun medication therapy with pancrelipase (Pancrease MT). The nurse
evaluates that the medication is having the optimal intended benefit if which effect is
observed? - Correct Answer - Reduction of steatorrhea
An older client recently has been taking cimetidine (Tagamet). The nurse monitors the
client for which most frequent central nervous system side effect of this medication? -
Correct Answer - Confusion
The client with a gastric ulcer has a prescription for sucralfate (Carafate), 1 g by mouth
four times daily. The nurse schedules the medication for which times? - Correct Answer
- One hour before meals and at bedtime
The client who chronically uses nonsteroidal anti-inflammatory drugs has been taking
misoprostol (Cytotec). The nurse determines that the medication is having the intended
pg. 2
,therapeutic effect if which of the following is noted? - Correct Answer - Relief of
epigastric pain
The client has been taking omeprazole (Prilosec) for 4 weeks. The ambulatory care
nurse evaluates that the client is receiving optimal intended effect of the medication if
the client reports the absence of which symptom? - Correct Answer - Heartburn
A client with a peptic ulcer is diagnosed with a Helicobacter pylori infection. The nurse is
reinforcing teaching for the client about the medications prescribed, including
clarithromycin (Biaxin), esomeprazole (Nexium), and amoxicillin (Amoxil). Which
statement by the client indicates the best understanding of the medication regimen? -
Correct Answer - "The medications will kill the bacteria and stop the acid production."
A histamine (H2)-receptor antagonist will be prescribed for a client. The nurse
understands that which medications are H2-receptor antagonists? Select all that apply. -
Correct Answer - 1. Nizatidine (Axid)
2. Ranitidine (Zantac)
3. Famotidine (Pepcid)
4. Cimetidine (Tagamet)
The nurse is analyzing the laboratory results of a client with leukemia who has received
a regimen of chemotherapy. Which laboratory value would the nurse specifically note as
a result of the massive cell destruction that occurred from the chemotherapy? - Correct
Answer - Increased uric acid level
The nurse is reinforcing medication instructions to a client with breast cancer who is
receiving cyclophosphamide (Neosar). The nurse tells the client to: - Correct Answer -
Increase fluid intake to 2000 to 3000 mL daily.
The client with non-Hodgkin's lymphoma is receiving daunorubicin (DaunoXome). Which
of the following would indicate to the nurse that the client is experiencing a toxic effect
related to the medication? - Correct Answer - Crackles on auscultation of the lungs
pg. 3
, A nurse is monitoring a client receiving desmopressin acetate (DDAVP) for adverse
effects to the medication. Which of the following indicates the presence of an adverse
effect? - Correct Answer - Drowsiness
A nurse reinforces instructions to a client who is taking levothyroxine (Synthroid). The
nurse tells the client to take the medication: - Correct Answer - On an empty stomach
A nurse reinforces medication instructions to a client who is taking levothyroxine
(Synthroid). The nurse instructs the client to notify the health care provider (HCP) if
which of the following occurs? - Correct Answer - Tremors
A nurse performs an admission assessment on a client who visits a health care clinic for
the first time. The client tells the nurse that propylthiouracil (PTU) is taken daily. The
nurse continues to collect data from the client, suspecting that the client has a history of:
- Correct Answer - Graves' disease
A nurse is reinforcing instructions for a client regarding intranasal desmopressin acetate
(DDAVP). The nurse tells the client that which of the following is a side effect of the
medication? - Correct Answer - Runny nose
A daily dose of prednisone is prescribed for a client. A nurse reinforces instructions to
the client regarding administration of the medication and instructs the client that the best
time to take this medication is: - Correct Answer - Early morning
A client is receiving acetylcysteine (Mucomyst), 20% solution diluted in 0.9% normal
saline by nebulizer. The nurse should have which item available for possible use after
giving this medication? - Correct Answer - Suction equipment
A client has a prescription to take guaifenesin (Humibid) every 4 hours, as needed. The
nurse determines that the client understands the most effective use of this medication if
the client states that he or she will: - Correct Answer - Take the tablet with a full glass of
water.
pg. 4
Exam 2026–2027 | Complete 250 Practice
Questions with Detailed Answer Rationales |
Comprehensive Practical Nursing Study
Guide
A client is taking Humulin NPH insulin daily every morning. The nurse reinforces
instructions for the client and tells the client that the most likely time for a hypoglycemic
reaction to occur is: - Correct Answer - 4 to 12 hours after administration
A client with diabetes mellitus visits a health care clinic. The client's diabetes mellitus
previously had been well controlled with glyburide (DiaBeta) daily, but recently the
fasting blood glucose level has been 180 to 200 mg/dL. Which medication, if added to
the client's regimen, may have contributed to the hyperglycemia? - Correct Answer -
Prednisone
A community health nurse visits a client at home. Prednisone 10 mg orally daily has
been prescribed for the client and the nurse reinforces teaching for the client about the
medication. Which statement, if made by the client, indicates that further teaching is
necessary? - Correct Answer - "I can take aspirin or my antihistamine if I need it."
Desmopressin acetate (DDAVP) is prescribed for the treatment of diabetes insipidus.
The nurse monitors the client after medication administration for which therapeutic
response? - Correct Answer - Decreased urinary output
A client with Crohn's disease is scheduled to receive an infusion of infliximab
(Remicade). The nurse assisting in caring for the client should take which action to
monitor the effectiveness of treatment? - Correct Answer - Checking the frequency and
consistency of bowel movements
pg. 1
,The home health care nurse is visiting a client who was recently diagnosed with type 2
diabetes mellitus. The client is prescribed repaglinide (Prandin) and metformin
(Glucophage) and asks the nurse to explain these medications. The nurse should
reinforce which instructions to the client? Select all that apply. - Correct Answer - 1.
Diarrhea can occur secondary to the metformin.
2. The repaglinide is not taken if a meal is skipped.
3. The repaglinide is taken 30 minutes before eating.
4. Candy or another simple sugar is carried and used to treat mild hypoglycemia
episodes.
The client has a PRN prescription for loperamide hydrochloride (Imodium). The nurse
understands that this medication is used for which condition? - Correct Answer - An
episode of diarrhea
The client has a PRN prescription for ondansetron (Zofran). For which condition should
this medication be administered to the postoperative client? - Correct Answer - Nausea
and vomiting
The client has begun medication therapy with pancrelipase (Pancrease MT). The nurse
evaluates that the medication is having the optimal intended benefit if which effect is
observed? - Correct Answer - Reduction of steatorrhea
An older client recently has been taking cimetidine (Tagamet). The nurse monitors the
client for which most frequent central nervous system side effect of this medication? -
Correct Answer - Confusion
The client with a gastric ulcer has a prescription for sucralfate (Carafate), 1 g by mouth
four times daily. The nurse schedules the medication for which times? - Correct Answer
- One hour before meals and at bedtime
The client who chronically uses nonsteroidal anti-inflammatory drugs has been taking
misoprostol (Cytotec). The nurse determines that the medication is having the intended
pg. 2
,therapeutic effect if which of the following is noted? - Correct Answer - Relief of
epigastric pain
The client has been taking omeprazole (Prilosec) for 4 weeks. The ambulatory care
nurse evaluates that the client is receiving optimal intended effect of the medication if
the client reports the absence of which symptom? - Correct Answer - Heartburn
A client with a peptic ulcer is diagnosed with a Helicobacter pylori infection. The nurse is
reinforcing teaching for the client about the medications prescribed, including
clarithromycin (Biaxin), esomeprazole (Nexium), and amoxicillin (Amoxil). Which
statement by the client indicates the best understanding of the medication regimen? -
Correct Answer - "The medications will kill the bacteria and stop the acid production."
A histamine (H2)-receptor antagonist will be prescribed for a client. The nurse
understands that which medications are H2-receptor antagonists? Select all that apply. -
Correct Answer - 1. Nizatidine (Axid)
2. Ranitidine (Zantac)
3. Famotidine (Pepcid)
4. Cimetidine (Tagamet)
The nurse is analyzing the laboratory results of a client with leukemia who has received
a regimen of chemotherapy. Which laboratory value would the nurse specifically note as
a result of the massive cell destruction that occurred from the chemotherapy? - Correct
Answer - Increased uric acid level
The nurse is reinforcing medication instructions to a client with breast cancer who is
receiving cyclophosphamide (Neosar). The nurse tells the client to: - Correct Answer -
Increase fluid intake to 2000 to 3000 mL daily.
The client with non-Hodgkin's lymphoma is receiving daunorubicin (DaunoXome). Which
of the following would indicate to the nurse that the client is experiencing a toxic effect
related to the medication? - Correct Answer - Crackles on auscultation of the lungs
pg. 3
, A nurse is monitoring a client receiving desmopressin acetate (DDAVP) for adverse
effects to the medication. Which of the following indicates the presence of an adverse
effect? - Correct Answer - Drowsiness
A nurse reinforces instructions to a client who is taking levothyroxine (Synthroid). The
nurse tells the client to take the medication: - Correct Answer - On an empty stomach
A nurse reinforces medication instructions to a client who is taking levothyroxine
(Synthroid). The nurse instructs the client to notify the health care provider (HCP) if
which of the following occurs? - Correct Answer - Tremors
A nurse performs an admission assessment on a client who visits a health care clinic for
the first time. The client tells the nurse that propylthiouracil (PTU) is taken daily. The
nurse continues to collect data from the client, suspecting that the client has a history of:
- Correct Answer - Graves' disease
A nurse is reinforcing instructions for a client regarding intranasal desmopressin acetate
(DDAVP). The nurse tells the client that which of the following is a side effect of the
medication? - Correct Answer - Runny nose
A daily dose of prednisone is prescribed for a client. A nurse reinforces instructions to
the client regarding administration of the medication and instructs the client that the best
time to take this medication is: - Correct Answer - Early morning
A client is receiving acetylcysteine (Mucomyst), 20% solution diluted in 0.9% normal
saline by nebulizer. The nurse should have which item available for possible use after
giving this medication? - Correct Answer - Suction equipment
A client has a prescription to take guaifenesin (Humibid) every 4 hours, as needed. The
nurse determines that the client understands the most effective use of this medication if
the client states that he or she will: - Correct Answer - Take the tablet with a full glass of
water.
pg. 4
