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RN ATI Pharmacology Exam: Latest Practice Questions

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A collection of ATI-style pharmacology exam questions for nursing students. The questions cover drug calculations, medication administration, adverse effects, contraindications, and nursing responsibilities for a wide array of drug classes, including cardiovascular, psychiatric, endocrine, and antibiotic agents.

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RN ATI Pharmacology LATEST ACTUAL EXAM 2026

A nurse is preparing to administer a scheduled dose of warfarin to a client. Which of the following
laboratory tests should the nurse review prior to administration?

A. PT
B. Total iron-binding capacity
C. WBC
D. PTT - CORRECT ANSWER-A. PT

A nurse is caring for a group of clients. Which of the following situations requires an incident report?
D

A. Client experiences a seizure.
B. A client vomits after receiving an oral medication.
O

C. A client receives their insulin 1 hours before scheduled.
D. A client receives their meal tray 20 min late. - CORRECT ANSWER-C. A client receives their
insulin 1 hour before scheduled.
N

A nurse is assessing a client who has received oxycodone. The nurse notes that the client's respiratory
rate is 8/min. The nurse should identify that which of the following is the pathophysiology for the
O

client's respiratory rate?
T

A. Oxycodone blocks the sodium channel suspending nerve conduction.
B. Oxycodone promotes vasodilation of cranial arteries.
C. Oxycodone causes central nervous system depression.
C

D. Oxycodone inhibits prostaglandin synthesis. - CORRECT ANSWER-C. Oxycodone causes central
nervous system depression.
O

A nurse is preparing to administer cefazolin 1 g in 0.9% sodium chloride 100 ml- via intermittent IV
PY

bolus over 30 min. The drop factor of the manual IV tubing is I5 gtt/mL. The nurse should set the
manual IV infusion to deliver how many gtt/min? (Round the answer to the nearest whole number. Use
a leading zero if it applies. Do not use a trailing zero.) - CORRECT ANSWER-50gtt/min

A nurse is preparing to transcribe a prescription for a client that reads "ondansetron 8 mg by mouth
every 12 hr PRN." Which of the following parts of the prescription should the nurse clarify with the
provider?

A. Dose
B. Route
C. Frequency
D. Reason - CORRECT ANSWER-D. Reason




1

,1. A nurse is caring for a client who has a prescription for nifedipine. Which of the following findings
should the nurse assess prior to administration of the medication?

A. Blood pressure
B. Respiratory rate
C. Temperature
D. Oxygen saturation - CORRECT ANSWER-A. Blood pressure

A nurse is providing teaching to a client who has a new prescription for carbamazepine for the
treatment of seizures. The nurse should instruct the client to monitor for which of the following adverse
effects?

A. Blurred vision
B. Insomnia
C. Metallic taste
D

D. Tachypnea - CORRECT ANSWER-A. Blurred vision

A nurse is reviewing the laboratory data of a client who is receiving filgrastim. Which of the following
O

laboratory values should the nurse monitor to evaluate the effectiveness of the treatment?

A. Potassium level
N

B. BUN
C. INR
O

D. WBC count - CORRECT ANSWER-D. WBC count
T

A nurse is caring for a client who is receiving parenteral nutrition and identifies that the client has
hypoglycemia. Which of the following actions should the nurse take?
C

A. Discontinue the infusion.
B. Administer IV dextrose.
O

C. Warm formula to room temperature.
D. Obtain arterial blood gases. - CORRECT ANSWER-B. Administer IV dextrose.
PY

A nurse is assessing a client who has septic shock and is receiving dopamine by continuous IV
infusion. Which of the following findings indicates that the nurse should increase the rate of infusion?

A. Headache
B. Hypotension
C. Chest pain
D. Extravasation - CORRECT ANSWER-B. Hypotension

A nurse is caring for a client who is taking warfarin and reports taking several new herbal supplements.
The nurse should identify which of the following supplements is contraindicated for concurrent use
with warfarin?

A. Ginkgo biloba
B. Coenzyme

2

,C. Valerian
D. Probiotics - CORRECT ANSWER-A. Ginkgo biloba

A nurse is assessing a client with hypertension who is receiving propranolol. Which of the following
findings requires the nurse's intervention?

A. Heart rate of 56/min
B. Sa02 95% on 2 L/min of oxygen
C. Respirations 22/min
D. Blood pressure 106/68 mm Hg - CORRECT ANSWER-A. HR of 56/min

A nurse is preparing to administer the varicella vaccine to a group of clients. The nurse should identify
which of the following clients as having a contraindication for receiving this immunization?

A. An older adult client living in a long-term care facility.
D

B. A young adult who has an allergy to eggs C. A child who recently received the human
papillomavirus vaccine.
D. A client who has AIDS - CORRECT ANSWER-D. A client who has AIDS
O

A nurse is caring for a client who is experiencing severe vomiting. Which of the following medications
should the nurse plan to administer?
N

A. Propafenone
O

B. Simvastatin
C. Prochlorperazine
T

D. Metformin - CORRECT ANSWER-C. Prochlorperazine

A nurse is preparing to administer filgrastim 5 mcg/kg/day subcutaneous to a client who weighs 143 lb.
C

How many mcg should the nurse administer per day? (Round the answer to the nearest whole number.
Use a leading zero if it applies. Do not use a trailing zero.) - CORRECT ANSWER-325mcg per day.
O

A nurse is caring for a client who develops an anaphylactic reaction to IV antibiotic administration.
After assessing the client's respiratory status and stopping the medication infusion. Which of the
PY

following actions should the nurse take next?

A. Administer epinephrine IM.
B. Replace the infusion with 0.9% sodium chloride.
C. Give diphenhydramine IM.
D. Elevate the client's legs and feet. - CORRECT ANSWER-A. Administer epinephrine IM.

A nurse is developing a teaching plan for an older adult client who has a new prescription for insulin
glargine. Which of the following expected outcomes should the nurse include in the plan?

A. The client will administer insulin glargine before each meal.
B. The client will use the deltoid muscle as an injection site.
C. The client will take an additional dose of insulin glargine prior to exercise.


3

, D. The client will wear his reading glasses when drawing up a dose of insulin glargine. - CORRECT
ANSWER-D. The client will wear his reading glasses when drawing up a dose of insulin glargine.

A nurse is preparing to administer medication to a client for the first time and needs to know about
potential food and medication interactions. Which of the following actions should the nurse take?

A. Have the client take the medication on an empty stomach to avoid interactions.
B. Consult a drug reference guide for possible interactions.
C. Ask another nurse if they are aware of potential interactions.
D. Check the client's medical record for medication and food interactions. - CORRECT ANSWER-B.
Consult a drug reference guide for possible interactions.

A nurse is taking a medication history from a client who has a new prescription for levothyroxine. The
nurse should instruct the client to wait 4 hr after taking levothyroxine before taking which of the
following supplements?
D

A. Ginkgo biloba
B. Calcium
O

C. Vitamin C
D. Zinc - CORRECT ANSWER-B. Calcium
N

A nurse is preparing to administer total parenteral nutrition to a client. Which of the following actions
should the nurse take?
O

A. Obtain the client's weight three times a week.
T

B. Check the client's WBC count daily.
C. Keep the solution refrigerated until 1 hr before infusion.
D. Change the solution every 36 hrs. - CORRECT ANSWER-C. Keep the solution refrigerated until 1
C

hr before infusion.
O

A nurse is preparing to administer a medication to a client. Using the rights of medication
administration. Which of the following actions should the nurse take to ensure the right medication is
administered to the client?
PY

A. Ask another nurse to check the medication dosage prior to administration.
B. Verify a written order with the medication administration record.
C. Use two client identifiers prior to administering the medication.
D. Document the full name of the prescribed medication after administration. - CORRECT ANSWER-
C. Use two client identifiers prior to administering the medication.

A nurse is preparing to mix short-acting insulin with NPH insulin from two vials. Which of the
following actions should the nurse take?

A. Inject air into the vial to withdraw the short-acting insulin.
B. Administer the insulin within 20 min of preparing it.
C. Ensure the NPH insulin is drawn into the syringe first.


4

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