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ATI Medication Administration & Dosage Calculation Practice Exam 2026–2027 | Comprehensive Practice Questions with Detailed Answer Rationales | Nursing Study Guide

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ATI Medication Administration & Dosage Calculation Practice Exam 2026–2027 | Comprehensive Practice Questions with Detailed Answer Rationales | Nursing Study Guide

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ATI Medication Administration & Dosage Calculation
Practice Exam 2026–2027 | Comprehensive Practice
Questions with Detailed Answer Rationales | Nursing
Study Guide

A client with dehydration receives a prescription for an IV of Lactated Ringer's 1,000 ml to be
administered over 8 hours. The nurse should program the infusion pump to deliver how many ml/hour?
(Enter numeric value only, using whole number.) - ANSWER - Use the ratio of: 1000 ml : 8 hours :: X : 1
hour

1000/X :: 8/1

X = 125 ml/hour



The nurse plans to administer labetalol hydrochloride (Trandate) 0.3 grams PO to a client with
hypertension. Trandate is available in 200 mg scored tablets. How many tablets should the nurse
administer? (Enter numeric value only.) - ANSWER - First convert grams to milligrams using the known
conversion: 1 gram = 1000 mg.

0.1 gram = 100 mg as 0.3 gram = 300 mg

Next using the formula, Desired/Available x 1 tablet =

300 mg/200 mg x 1 = 1.5 tablets



A nurse is preparing to administer sucralfate 1 g PO twice daily to a client. Available is sucralfate 1,000
mg tablets. How many tablets should the nurse administer per dose? - ANSWER - 1 tablet



A nurse is preparing to administer epinephrine hydrochloride 0.5 mg subcutaneous stat. How many mcg
should the nurse administer? - ANSWER - 500 mcg



A nurse is preparing to administer diphenhydramine 25 mg PO every 6 hr. Available is diphenhydramine
syrup 12.5mg/5mL. How many tsp should the nurse administer per dose? - ANSWER - 2 tsp



A nurse is preparing to administer digoxin 0.125 mg PO at 9:00 a.m. At which of the following times
should the nurse administer the medication?




pg. 1

,1500

0900

1700

2100 - ANSWER – 0900

The healthcare provider prescribes furosemide (Lasix) 25 mg IV. The drug is available in a solution of 40
mg/4ml. How many ml should the nurse administer? (Enter numeric value only. If rounding is required,
round to the nearest tenth.) - ANSWER - Using the formula D/H x Q: 25 mg/40 mg x 4 ml = 2.5 ml



A client with impetigo receives a prescription for azithromycin (Zithromax) 500 mg PO on day 1, then
250 mg/day on days 2 through 5 for a total administration of 1.5 gram. The pharmacy has 250 mg
tablets available. How many tablets total should the nurse give to the client for the duration of
treatment? (Enter numeric value only.) - ANSWER - Using Desired/Have available formula:

500 mg/250 mg x 1 times a day = 2 tablets on Day 1.

Days 2 to 5: 1 tablet each day = 4 tablets. 2+4 = 6.



A nurse is preparing to administer regular insulin 15 units and isophane insulin 40 units subcutaneous at
6:30 a.m. At which of the following times should the nurse administer the medication?



0430

1630

0630

1430 - ANSWER - 0630



A nurse is preparing to administer cephalexin 0.25 g PO every 6 hr. Available is cephalexin 500 mg
tablets. How many tablets should the nurse administer per dose? - ANSWER - 0.5 tablets



A nurse is preparing to administer levothyroxine 0.075 mg PO to a client. Available is levothyroxine 25
mcg tablets. How many tablets should the nurse administer? - ANSWER - 3 tablets



A nurse is preparing to administer furosemide 40 mg PO in 0.5 oz of orange juice. How many mL of
orange juice should the nurse administer? - ANSWER - 15 mL




pg. 2

, A nurse is preparing to administer 0.9% sodium chloride 2,500 mL to infuse over 12 hr. The nurse should
administer how many L? - ANSWER - 2.5 L



A nurse is preparing to administer potassium chloride powder 20 mEq PO in 6 oz of water. How many mL
of water should the nurse administer? - ANSWER - 180 mL



A nurse is preparing to administer 650 mg of acetaminophen syrup to a client. The amount available is
acetaminophen syrup 160mg/5mL. How many tsp should the nurse administer per dose? - ANSWER - 4
tsp



A nurse is preparing to administer digoxin 250 mcg PO daily. Available is digoxin 0.125 mg tablets. How
many tablets should the nurse administer? - ANSWER - 2 tablets



A nurse is preparing a medication and calculates the dosage as 0.547 mL. Rounding this amount to the
nearest hundredth, the nurse should administer how many mL? - ANSWER - 0.55 mL



A nurse should use which of the following units when measuring weight?



Gram

Liter

Meter

Milliliter - ANSWER - Gram



A nurse is teaching a class about error - prone abbreviations in medication prescriptions. The nurse
should include that which of the following prescriptions has acceptable abbreviations?



Metoclopramide 10 mg IM Q6H PRN nausea

Desipramine 100 mg PO QD

Enoxaparin 30 mg sub q 2 hr before surgery

MSO4 10 mg IM Q3H PRN pain - ANSWER - Metoclopramide 10 mg IM Q6H PRN nausea




pg. 3

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