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What is the function of the pericardium? Answer: Isolates the heart from other thoracic
structures, maintains its position, prevents overfilling, and serves as a barrier to infection.
Differentiate between acute and chronic pericarditis. Answer: Acute pericarditis is inflammation
of the pericardium lasting less than 2 weeks, while chronic pericarditis persists longer.
What is cardiac tamponade? Answer: A condition where fluid accumulation in the pericardial
cavity compresses the heart, impairing its ability to pump blood.
What is acute coronary syndrome (ACS)? Answer: A term that encompasses unstable angina and
myocardial infarction, indicating a sudden reduction in blood flow to the heart.
Distinguish between unstable angina and stable angina. Answer: Unstable angina occurs
unpredictably and is more severe, while stable angina is predictable and usually triggered by
exertion.
What are the types of myocardial infarction? Answer: Non-ST-segment elevation myocardial
infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI).
Define cardiomyopathy. Answer: A disease of the heart muscle that affects its size, shape, and
ability to pump blood.
Differentiate between hypertrophic cardiomyopathy and dilated cardiomyopathy. Answer:
Hypertrophic cardiomyopathy involves thickening of the heart muscle, while dilated
cardiomyopathy involves enlargement and weakening of the heart.
What is infective endocarditis? Answer: An infection of the inner lining of the heart, often
caused by bacteria, leading to inflammation and damage to heart valves.
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,What are the main causes of heart failure? Answer: Coronary artery disease, hypertension,
cardiomyopathy, and valvular heart disease.
What is the Frank-Starling mechanism? Answer: A physiological principle where the heart's
stroke volume increases in response to an increase in the volume of blood filling the heart.
Differentiate between high-output and low-output heart failure. Answer: High-output heart
failure occurs when the heart pumps more blood than normal, while low-output heart failure
occurs when it pumps less.
What is the role of the renin-angiotensin-aldosterone system in heart failure? Answer: It
regulates blood pressure and fluid balance, which can contribute to heart failure if overactivated.
What is the significance of the foramen ovale in fetal circulation? Answer: It allows blood to
bypass the non-functioning fetal lungs by connecting the right and left atria.
What are common congenital heart defects? Answer: Atrial septal defects, ventricular septal
defects, and tetralogy of Fallot.
What is Kawasaki disease? Answer: An acute, self-limited vasculitis that primarily affects
children and can lead to coronary artery complications.
What are the complications of shock? Answer: Can affect the lungs, kidneys, gastrointestinal
tract, and lead to blood clotting disorders.
What is the difference between cardiogenic and hypovolemic shock? Answer: Cardiogenic
shock is due to heart failure, while hypovolemic shock is due to significant blood or fluid loss.
How does valvular heart disease affect hemodynamic function? Answer: It can cause
regurgitation or stenosis, leading to altered blood flow and increased workload on the heart.
What is the impact of aging on heart failure? Answer: Increased prevalence due to cumulative
effects of cardiovascular disease and decreased physiological reserve.
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, What is the role of natriuretic peptides in heart failure? Answer: They help regulate blood
volume and pressure, counteracting the effects of fluid overload.
What are the symptoms of heart failure? Answer: Shortness of breath, fatigue, swelling in legs
and ankles, and rapid or irregular heartbeat.
What is the purpose of population-based public health measures for CVD? Answer: To reduce
morbidity, mortality, and costs associated with cardiovascular diseases.
What is the primary function of heart valves? Answer: To ensure unidirectional blood flow
through the heart chambers.
What is the significance of serum cardiac markers? Answer: They help diagnose and assess the
severity of myocardial infarction and other cardiac conditions.
What are the common treatments for cardiomyopathy? Answer: Medications, lifestyle changes,
and in severe cases, surgical interventions or heart transplantation.
What are some causes of acute pericarditis? Answer: Bacterial or mycobacterial infections,
connective tissue diseases, uremia, post cardiac surgery, neoplastic invasion, radiation, trauma,
drug toxicity, and contiguous inflammatory processes.
What is a common characteristic of acute pericarditis? Answer: Increased capillary permeability
in the serous pericardium.
What is the typical exudate associated with acute pericarditis? Answer: A fibrinous exudate that
may heal by resolution or lead to scar tissue and adhesions.
What are the clinical manifestations of acute pericarditis? Answer: A triad of chest pain,
pericardial friction rub, and electrocardiographic (ECG) changes.
How does chest pain from acute pericarditis typically present? Answer: Abrupt onset, sharp,
located in the precordial area, may radiate to neck, back, abdomen, or side.
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