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ATI Comprehensive Review 2026–2027 | Complete 500+ Practice Questions with Detailed Answer Rationales | Comprehensive Nursing Study Guide

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ATI Comprehensive Review 2026–2027 | Complete 500+ Practice Questions with Detailed Answer Rationales | Comprehensive Nursing Study Guide

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ATI Comprehensive Review 2026–2027 |
Complete 500+ Practice Questions with Detailed
Answer Rationales | Comprehensive Nursing
Study Guide


A registered nurse (RN) is discussing the overall fluid balance of an assigned client. The
RN calculates that the client's insensible fluid loss is approximately 500 mL/day. The
licensed practical nurse (LPN) recalls that the RN is referring to fluid losses occurring
through which of the following areas?

1. Nasogastric tube and wound drain

2. Foley catheter and nasogastric tube

3. Wound drain and skin

4. Skin and lungs - Correct Answer - 4


A nurse is assisting in the care of a group of clients on the nursing unit. The nurse
determines that a client with which of the following diagnoses is the one who has the
least amount of risk for developing third-spacing of body fluid?

1. Laënnec's cirrhosis

2. Ischemic stroke

3. Major burn

4. Renal failure - Correct Answer - 2


An older adult client is admitted with a diagnosis of pneumonia and dehydration. The
nurse monitors the client for which of the following manifestations that correlates with
this client's fluid imbalance?

1. Flat neck veins

2. Lung crackles



pg. 1

,3. Increased blood pressure

4. Decreased pulse - Correct Answer - 1

A nurse is administering a dose of a prescribed diuretic to an assigned client. The nurse
would plan to monitor the client for hypokalemia as a side effect of therapy if the client
were receiving which of the following medications?

1. Spironolactone (Aldactone)

2. Bumetanide (Bumex)

3. Triamterene (Dyrenium)

4. Amiloride HCl (Midamor) - Correct Answer - 2


A nurse is assisting in the care of a client who is at risk for hyponatremia. The nurse
would monitor this client for which of the following manifestations of this electrolyte
imbalance?

1. Slow pulse rate

2. High blood pressure

3. Flaccid muscles

4. Abdominal cramping - Correct Answer - 4


A nurse is planning to reinforce dietary teaching about foods that are low in potassium
to a client receiving a potassium-sparing diuretic. The nurse would be sure to include
which of the following on a list of foods that have a low potassium content?

1. Spinach

2. Avocado

3. Fresh pork

4. White bread - Correct Answer - 4


A nurse is obtaining the intershift report for a group of assigned clients. The nurse plans
to monitor which client for signs of hyperkalemia because of the physiology associated
with the health problem?



pg. 2

,1. A client with a new burn injury

2. A client with Cushing's syndrome

3. A client with ulcerative colitis

4. A client who has a history of long-term laxative abuse - Correct Answer - 1


A nurse is monitoring a client for hypercalcemia. Which of the following would the nurse
note in hypercalcemia?

1. Slight muscle weakness

2. Tingling sensations

3. Hyperactive reflexes

4. Muscle cramps - Correct Answer - 1


A nurse is caring for a client with Paget's disease who has an elevated serum calcium
level of 12.3 mEq/L. The nurse checks to see that which of the following medications is
available in the stock medication supply area for possible use to reverse this elevation?

1. Calcium gluconate

2. Calcium chloride

3. Calcitonin (Calcimar)

4. Vitamin D - Correct Answer - 3


A client with diabetes mellitus has a blood glucose on admission of 596 mg/dL. The
nurse anticipates that this client would be experiencing which of the following types
of acid-base imbalance? 1. Metabolic acidosis

2. Metabolic alkalosis

3. Respiratory acidosis

4. Respiratory alkalosis - Correct Answer - 1




pg. 3

, A nurse is assisting to admit a client with a diagnosis of Guillain-Barré syndrome. The
nurse knows that if the disease is severe enough, the client will be at risk for which of
the following acid-base imbalances?

1. Metabolic acidosis

2. Metabolic alkalosis

3. Respiratory acidosis

4. Respiratory alkalosis - Correct Answer - 3

A licensed practical nurse (LPN) is assisting in the care of a pregnant teen-aged client
with preeclampsia receiving magnesium sulfate. The LPN plans to notify the registered
nurse immediately if which sign of magnesium toxicity is noted?

1. Respiratory rate of 10 breaths per minute

2. Serum magnesium level of 5 mEq/L

3. Proteinuria

4. Hyperactive deep tendon reflexes - Correct Answer - 1


A nurse has a routine order to instill erythromycin ointment (Ilotycin) into the eyes of a
newborn. The nurse explains to the parents that the purpose of the medication is to:

1. Help the newborn to see more clearly.

2. Guard against infection acquired during intrauterine life.

3. Ensure the sterility of the conjunctiva in the newborn.
4. Protect the newborn from contracting an eye infection from the birth process. -
Correct Answer - 4


A licensed practical nurse (LPN) is caring for a client in preterm labor who is receiving
an infusion of ritodrine hydrochloride, when the client suddenly begins to complain of
shortness of breath. The LPN should take which action first?

1. Notify the registered nurse.

2. Count the respiratory rate for at least 2 minutes.

3. Bring a manual resuscitation bag to the bedside.



pg. 4

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