,PHARMACOLOGY FOR NURSES: A PATHOPHYSIOLOGIC
APPROACH, 8TH EDITION – UPDATED TEST BANK
CHAPTER 1: ORIENTATION TO PHARMACOLOGY
PART A: MULTIPLE CHOICE QUESTIONS (25 Questions)
1. The nurse is teaching a patient how a medication works to treat an illness. To do
this, the nurse will rely on knowledge of:
A) Clinical pharmacology
B) Drug efficacy
C) Pharmacokinetics
D) Pharmacotherapeutics
Answer: D
Rationale: Pharmacotherapeutics is the branch of pharmacology that deals
with the uses of drugs to treat, prevent, and diagnose disease. Clinical
pharmacology focuses on drug effects in humans. Pharmacokinetics is how
the body acts on drugs. Drug efficacy refers to the ability of a drug to
produce a therapeutic effect. Nurses must understand
pharmacotherapeutics to educate patients about how medications work to
treat their specific conditions (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies
Learning Outcome: 1-1 Define pharmacology and related terms
2. A physician has ordered intramuscular (IM) injections of morphine, a narcotic,
every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is
,aware this drug has a high abuse potential. Under what category would morphine
be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Answer: B
Rationale: Narcotics with a high abuse potential are classified as Schedule
II drugs because of severe dependence liability. Schedule I drugs have high
abuse potential and no accepted medical use. Schedule III drugs have a
lesser abuse potential than II and an accepted medical use. Schedule IV
drugs have low abuse potential and limited dependence liability.
Understanding controlled substance scheduling is essential for safe
medication administration and legal compliance (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies Learning Outcome: 1-2 Identify the legal classifications of
controlled substances
3. When involved in phase III drug evaluation studies, what responsibilities would
the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Answer: C
Rationale: Phase III studies involve use of a drug in a vast clinical population in
which patients are asked to record any symptoms they experience while taking
the drugs. Nurses may be responsible for helping collect and analyze the
information to be shared with the FDA. Use of animals in drug testing is done in
the preclinical trials. Patients who are involved in phase II studies are monitored
, closely for drug action and adverse effects. Phase I studies involve healthy human
volunteers who are usually paid for their participation (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies
Learning Outcome: 1-3 Describe the phases of drug testing and approval
4. What concept is considered when generic drugs are substituted for brand name
drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Answer: A
Rationale: Bioavailability is the portion of a dose of a drug that reaches the
systemic circulation and is available to act on body cells. Binders used in a
generic drug may not be the same as those used in the brand name drug.
Therefore, the way the body breaks down and uses the drug may differ,
which may eliminate a generic drug substitution. Critical concentration is
the amount of a drug that is needed to cause a therapeutic effect and
should not differ between generic and brand name medications.
Distribution and half-life should not change when substituting a generic
medication (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies Learning Outcome: 1-4 Compare and contrast generic and
brand-name drugs
APPROACH, 8TH EDITION – UPDATED TEST BANK
CHAPTER 1: ORIENTATION TO PHARMACOLOGY
PART A: MULTIPLE CHOICE QUESTIONS (25 Questions)
1. The nurse is teaching a patient how a medication works to treat an illness. To do
this, the nurse will rely on knowledge of:
A) Clinical pharmacology
B) Drug efficacy
C) Pharmacokinetics
D) Pharmacotherapeutics
Answer: D
Rationale: Pharmacotherapeutics is the branch of pharmacology that deals
with the uses of drugs to treat, prevent, and diagnose disease. Clinical
pharmacology focuses on drug effects in humans. Pharmacokinetics is how
the body acts on drugs. Drug efficacy refers to the ability of a drug to
produce a therapeutic effect. Nurses must understand
pharmacotherapeutics to educate patients about how medications work to
treat their specific conditions (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies
Learning Outcome: 1-1 Define pharmacology and related terms
2. A physician has ordered intramuscular (IM) injections of morphine, a narcotic,
every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is
,aware this drug has a high abuse potential. Under what category would morphine
be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Answer: B
Rationale: Narcotics with a high abuse potential are classified as Schedule
II drugs because of severe dependence liability. Schedule I drugs have high
abuse potential and no accepted medical use. Schedule III drugs have a
lesser abuse potential than II and an accepted medical use. Schedule IV
drugs have low abuse potential and limited dependence liability.
Understanding controlled substance scheduling is essential for safe
medication administration and legal compliance (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies Learning Outcome: 1-2 Identify the legal classifications of
controlled substances
3. When involved in phase III drug evaluation studies, what responsibilities would
the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Answer: C
Rationale: Phase III studies involve use of a drug in a vast clinical population in
which patients are asked to record any symptoms they experience while taking
the drugs. Nurses may be responsible for helping collect and analyze the
information to be shared with the FDA. Use of animals in drug testing is done in
the preclinical trials. Patients who are involved in phase II studies are monitored
, closely for drug action and adverse effects. Phase I studies involve healthy human
volunteers who are usually paid for their participation (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies
Learning Outcome: 1-3 Describe the phases of drug testing and approval
4. What concept is considered when generic drugs are substituted for brand name
drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Answer: A
Rationale: Bioavailability is the portion of a dose of a drug that reaches the
systemic circulation and is available to act on body cells. Binders used in a
generic drug may not be the same as those used in the brand name drug.
Therefore, the way the body breaks down and uses the drug may differ,
which may eliminate a generic drug substitution. Critical concentration is
the amount of a drug that is needed to cause a therapeutic effect and
should not differ between generic and brand name medications.
Distribution and half-life should not change when substituting a generic
medication (Adams et al., 2025).
Page Ref: Chapter 1
Cognitive Level: Applying
Client Need/Sub: Physiological Integrity: Pharmacological and Parenteral
Therapies Learning Outcome: 1-4 Compare and contrast generic and
brand-name drugs
