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Clinical Chemistry by ELSEVIER
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, 1. Which of the following is considered a lipid? 1. c. Chylomicrons, low-density lipoprotein(LDL), and high-density lipoprotein
a. Chylomicrons (HDL) are considered to be lipoproteins that transport lipids throughout the body;
b. LDL cholesterol is classified as a lipid.
c. Cholesterol
d. HDL
2. In the laboratory procedure for the quantification of 2. d. Dextran sulfate precipitates all Apo B-containing lipoproteins (chylomicrons,
HDL, the purpose of the dextran sulfate is to: very-low-density lipoprotein [VLDL], intermediate density lipoprotein [IDL], and
a. Precipitate all Apo A1 containing lipoproteins low-density lipoprotein [LDL]) leaving high-density lipoprotein (HDL) (Apo A-
b. Covert cholesterol esters to cholesterol for detection containing lipoprotein) in the supernatant. HDL is then mixed with the reagent
c. Precipitate all Apo B and Apo A containing lipoproteins cholesterol esterase and cholesterol oxidase to quantitate HDL concentrations.
d. Precipitate all Apo B containing proteins
3. Which of the following lipoproteins is the smallest of all 3. a. Lipoproteins are characterized by size and density. High-density lipoprotein
the lipoproteins and is composed of 50% protein? (HDL) is the smallest, most dense lipoprotein, carrying 50% of its weight as
a. HDL protein.
b. Chylomicrons
c. LDL
d. Triglycerides
4. Which of the following would be most adversely 4. d. Triglycerides are most adversely affected by recent food intake, and
affected by a non-fasting sample? therefore a fast is always recommended for triglyceride analysis.
a. HDL
b. LDL
c. Cholesterol
d. Triglycerides
5. Which of the following apoproteins is responsible for 5. c. Apo E is a ligand for the low-density lipoprotein (LDL) receptor, reverses
receptor binding for IDL and the chylomicron remnant cholesterol transport, and is a regulator of cell growth and immune responses.
produced in fat transport?
a. Apo A1
b. Apo C
c. Apo E
d. Apo B
6. Which of the following enzymes is found bound to 6. c. Two enzymes are responsible for esterifying cholesterol, lecithin-cholesterol
HDL and LDL in blood plasma and acts to convert free acyl transferase (extracellular), and acetyl coenzyme A (acyl- CoA) cholesterol
cholesterol into cholesteryl esters? acyltransferase (intracellular).
a. Cholesterol esterase
b. Cholesterol oxidase
c. Lecithin-cholesterol acyltransferase
d. Lipase
7. Which of the following blood samples would serve 7. a. Although lipoproteins can be assayed using a variety of anticoagulants, the
best to assay lipoproteins because this anticoagulant preferred anticoagulant is ethylenediaminetetraacetic acid (EDTA) because it
acts to preserve lipoproteins? preserves lipoproteins over time.
a. EDTA plasma sample
b. Heparin plasma sample
c. Citrate plasma sample
d. Fluoride plasma sample
8. Exogenous triglycerides are transported in the plasma 8. b. Triglycerides are transported throughout the body by means of two
in which of the following forms? lipoproteins: very-low-density lipoprotein (VLDL) and chylomicrons. VLDL carries
a. VLDL endogenously derived triglycerides, and chylomicrons carry exogenously derived
b. Chylomicrons triglycerides.
c. LDL
d. Cholesteryl esters
9. A patient presents to his physician for a lipid profile. 9. b. Low-density lipoprotein (LDL) cholesterol is calculated as follows: LDL TC
The following results are received: HDL 50 mg/dL Total HDL + TG=5 LDL 300 50 + 200=5 LDL 300 90 LDL 210 mg=dL
cholesterol 300 mg/dL Triglycerides 200 mg/dL The
calculated LDL cholesterol is:
a. 200
b. 210
c. 290
d. 350
Clinical Chemistry by ELSEVIER
** Expert-Verified Explanation
** Questions with Verified Answer
** New Edition | Updated
** 100% Guaranteed Pass
** 100% Correct Answers | Graded A+
, 1. Which of the following is considered a lipid? 1. c. Chylomicrons, low-density lipoprotein(LDL), and high-density lipoprotein
a. Chylomicrons (HDL) are considered to be lipoproteins that transport lipids throughout the body;
b. LDL cholesterol is classified as a lipid.
c. Cholesterol
d. HDL
2. In the laboratory procedure for the quantification of 2. d. Dextran sulfate precipitates all Apo B-containing lipoproteins (chylomicrons,
HDL, the purpose of the dextran sulfate is to: very-low-density lipoprotein [VLDL], intermediate density lipoprotein [IDL], and
a. Precipitate all Apo A1 containing lipoproteins low-density lipoprotein [LDL]) leaving high-density lipoprotein (HDL) (Apo A-
b. Covert cholesterol esters to cholesterol for detection containing lipoprotein) in the supernatant. HDL is then mixed with the reagent
c. Precipitate all Apo B and Apo A containing lipoproteins cholesterol esterase and cholesterol oxidase to quantitate HDL concentrations.
d. Precipitate all Apo B containing proteins
3. Which of the following lipoproteins is the smallest of all 3. a. Lipoproteins are characterized by size and density. High-density lipoprotein
the lipoproteins and is composed of 50% protein? (HDL) is the smallest, most dense lipoprotein, carrying 50% of its weight as
a. HDL protein.
b. Chylomicrons
c. LDL
d. Triglycerides
4. Which of the following would be most adversely 4. d. Triglycerides are most adversely affected by recent food intake, and
affected by a non-fasting sample? therefore a fast is always recommended for triglyceride analysis.
a. HDL
b. LDL
c. Cholesterol
d. Triglycerides
5. Which of the following apoproteins is responsible for 5. c. Apo E is a ligand for the low-density lipoprotein (LDL) receptor, reverses
receptor binding for IDL and the chylomicron remnant cholesterol transport, and is a regulator of cell growth and immune responses.
produced in fat transport?
a. Apo A1
b. Apo C
c. Apo E
d. Apo B
6. Which of the following enzymes is found bound to 6. c. Two enzymes are responsible for esterifying cholesterol, lecithin-cholesterol
HDL and LDL in blood plasma and acts to convert free acyl transferase (extracellular), and acetyl coenzyme A (acyl- CoA) cholesterol
cholesterol into cholesteryl esters? acyltransferase (intracellular).
a. Cholesterol esterase
b. Cholesterol oxidase
c. Lecithin-cholesterol acyltransferase
d. Lipase
7. Which of the following blood samples would serve 7. a. Although lipoproteins can be assayed using a variety of anticoagulants, the
best to assay lipoproteins because this anticoagulant preferred anticoagulant is ethylenediaminetetraacetic acid (EDTA) because it
acts to preserve lipoproteins? preserves lipoproteins over time.
a. EDTA plasma sample
b. Heparin plasma sample
c. Citrate plasma sample
d. Fluoride plasma sample
8. Exogenous triglycerides are transported in the plasma 8. b. Triglycerides are transported throughout the body by means of two
in which of the following forms? lipoproteins: very-low-density lipoprotein (VLDL) and chylomicrons. VLDL carries
a. VLDL endogenously derived triglycerides, and chylomicrons carry exogenously derived
b. Chylomicrons triglycerides.
c. LDL
d. Cholesteryl esters
9. A patient presents to his physician for a lipid profile. 9. b. Low-density lipoprotein (LDL) cholesterol is calculated as follows: LDL TC
The following results are received: HDL 50 mg/dL Total HDL + TG=5 LDL 300 50 + 200=5 LDL 300 90 LDL 210 mg=dL
cholesterol 300 mg/dL Triglycerides 200 mg/dL The
calculated LDL cholesterol is:
a. 200
b. 210
c. 290
d. 350
