Chapter 3 : McCance Huether
Pathophysiology
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, intracellular fluid (ICF) fluid within cells
extracellular fluid (ECF) fluid outside cells
total body water (TBW) sum of all fluds
varies with age and amount of body fat
osmosis process by which water moves between ICF and ECF compartments
net filtration movement across the capillary law
described according to the Starling equation
edema problem of fluid distribution that results in accumulation of fluid within the
interstitial spaces
edema causes venous or lymphatic obstruction (increases hydrostatic pressure)
plasma protein losses (decreases plasma oncotic pressure)
increased capillary permeability
increased vascular volume
edema pathophysiology related to an increase in forces favoring fluid filtration from capillaries into tissues
edema s/sx swelling and puffiness
tighter-fitting clothes and shoes
limited movement of the affected area
weight gain
sodium balance regulation aldosterone increased reabsorption of sodium by the distal tubule of the kidney
renin and angiotensin enzymes that promote or injibit secretion of aldosterone, regulating sodium and
water balance
atrial natriuretic hormone decreases renal tubular resorption and promotes urinary excretion of sodium
water balance regulated by thirst and antidiuretic hormone
antidiuretic homone initiated by an increase in plasma osmolality or a decrease in circulating blood
volume
water balance alterations isotonic
hypertonic
hypotonic
isotonic alteration occurs when changes in TBW are accompanied by proportional changes in
concentrations of electrolytes