Study Questions with Expert Graded
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1. Pure Food and Drug Act (1906) - ANSWER Forbade the manufacture, sale,
and transportation of adulterated or mislabeled foods and drugs.
2. Shirley Amendment of 1912 - ANSWER Prevented fraudulent therapeutic
claims by drug manufacturers
3. Harrison Act of 1914 - ANSWER Established the word narcotic and
required the use of a stamp on narcotic drug containers. Also regulated the
importation, manufacture, sale, and use of opium, codeine, and their
derivatives
4. Food, Drug, and Cosmetic Act of 1938 - ANSWER A New drug could not
be marketed until proven safe, tested for toxicity, and required adverse drug
effects to be reported.
5. drug blood level - ANSWER amount of a drug present in the blood
6. plasma binding - ANSWER when proteins bind to drugs and decrease the
amount of free-flowing drug in the bloodstream allowing the drug to stay in
the body for longer.
7. Examples of Sulfonamides - ANSWER Sulfamethoxazole, sulfisoxazole,
sulfadiazine
,8. Uses for Sulfonamides - ANSWER Treating UTIs, Ulcerative colitis, 2nd
and 3rd degree burns
9. Drugs that interact with Sulfonamides - ANSWER Oral anticoagulants,
methotrexate, and hydrations
10.What are the 4 groups of penicillin? - ANSWER Natural penicillins,
penicillinase-resistant penicillins, aminopenicillins, extended-spectrum
penicillins
11.Uses for Penicillin - ANSWER UTIs, Septicemia, Meningitis, Intra-
Abdominal infections, Sexually Transmitted Infections (syphilis),
Pneumonia and other respiratory infections
12.What variables can effect drug dosage? - ANSWER Weight, Age, Height,
Gender, Genetics, Diet
13.Another name for antianxiety drugs - ANSWER Anxiolytics
14.Benzodiazepines - ANSWER category 4 meds
15.3 Examples of antianxiety drugs - ANSWER alprazolam, doxepin,
lorazepam
16.Acronym for cancer in adults? - ANSWER CAUTION
,17.Durham-Humphrey Amendment (1951) - ANSWER Replaced Laws of
1938. Required designation of whether or not the drug was prescription or
OTC
18.Schedule I - ANSWER This type of drug has no accepted medical use in the
United States and has a high potential for abuse
19.Schedule II drugs - ANSWER Accepted for medical use but with severe
restrictions (high potential for abuse)
20.Schedule III drugs - ANSWER Have low potential for abuse with an
accepted medical use. Prescription only
21.Schedule IV - ANSWER Abuse potential exists, but less than Sch III.
Examples are: Ambien, Darvocet and Lorazepam.
22.Schedule V drugs - ANSWER Lowest potential for abuse. May be sold
OTC to people that show ID
23.Kefauver-Harris Amendment (1962) - ANSWER Requires proof of safety
and efficacy of a drug for approval before marketing
24.Controlled Substances Act (1970) - ANSWER Replaced all laws passed
prior to it concerning drug control. 5 drug schedules put in place based on
potential for abuse.
25.Poison Prevention Packaging Act (1970) - ANSWER Implemented child
resistant packaging
, 26.Drug Listing Act of 1972 - ANSWER drugs must have a National Drug
Code number.
27.Drug Regulation and Reform Act of 1978 - ANSWER Quicker
development and distribution of new drugs
28.Orphan Drug Act of 1983 - ANSWER Established funding for research of
rare chronic illnesses for new and old drugs.
29.Drug Price Competition and Patent Term Restoration Act of 1984 -
ANSWER Eased requirements for marketing generic drugs
30.Omnibus Budget Reconciliation Act (OBRA 1990) - ANSWER Mandated
that OTC drugs be documented
31.Anabolic Steroid Control Act of 1990 - ANSWER placed all into category
III drugs (CSA)
32.Prescription Drug Amendments of 1992 - ANSWER Allowed rapid
approval of drugs for life-threatening diseases
33.Food and Drug Administration Modernization Act of 1997 - ANSWER
Allowed rapid approval of drugs by the FDA
34.Pharmacokinetics - ANSWER the movement of drugs through the body via
absorption, distribution, metabolism, and excretion
What are the common signs of childhood cancer and the abbriviation? -
ANSWER CHILD CANCER