PC707 Final Exam Questions and Answers
with Verified Solutions | Latest Updated 2026
Fluoroquinolones Psych side effects
CI=Marfans, HTN, atherosclerotic disease,
renal
disease, pregnancy, and those less than
18.
caution: elderly and DM
BBW=tendon rupture
increased risk for C-diff
Aminoglycosides Ototoxic, neurotoxic, nephrotoxic
Flagyl GI upset
BBW=increased carciogenic effect
No need to worry about the timing of
alcohol
ingestion
Rifampin CYP450 inducer (decrease levels of birth
control)
Hepatotoxicity
Change color of urine
Isoniazid Low B6 (HIV, DM, lact, preg)
Hepatotoxic
Cannot give as single agent (TB
resistance)
BBW=severe hepatitis, failure death
, Prep Daily med
Check liver and kidney function
NEED to be HIV neg
BBW=resistant HIV if HIV positive
Macrolides Prolongued QT
Many d2d
Sulfonamides increase INR with warfarin
hyperkalemia with ACE, ARB, kidney
disease
no in preg in 1st and 3rd trimester
no infants G6PD or hyperbilirubinemia
Special population Elderly: toxic levels
Pregnancy: no teratogenic drugs ~ TDAP
Lactation:
Children: penicillin, ceph, macrolides
BEST
QT prolong -mycins
chloroquine
antifungals
Antifungals no with statins
CYP450 inhibitors
with Verified Solutions | Latest Updated 2026
Fluoroquinolones Psych side effects
CI=Marfans, HTN, atherosclerotic disease,
renal
disease, pregnancy, and those less than
18.
caution: elderly and DM
BBW=tendon rupture
increased risk for C-diff
Aminoglycosides Ototoxic, neurotoxic, nephrotoxic
Flagyl GI upset
BBW=increased carciogenic effect
No need to worry about the timing of
alcohol
ingestion
Rifampin CYP450 inducer (decrease levels of birth
control)
Hepatotoxicity
Change color of urine
Isoniazid Low B6 (HIV, DM, lact, preg)
Hepatotoxic
Cannot give as single agent (TB
resistance)
BBW=severe hepatitis, failure death
, Prep Daily med
Check liver and kidney function
NEED to be HIV neg
BBW=resistant HIV if HIV positive
Macrolides Prolongued QT
Many d2d
Sulfonamides increase INR with warfarin
hyperkalemia with ACE, ARB, kidney
disease
no in preg in 1st and 3rd trimester
no infants G6PD or hyperbilirubinemia
Special population Elderly: toxic levels
Pregnancy: no teratogenic drugs ~ TDAP
Lactation:
Children: penicillin, ceph, macrolides
BEST
QT prolong -mycins
chloroquine
antifungals
Antifungals no with statins
CYP450 inhibitors
