Advanced Pharmacology for Care of the
Family Questions & Answers {Grade A}
100% Correct – Chamberlain
Lithium - Correct answer drug of choice for controlling manic episodes and for long
term ppx against recurrence of mania or depression. monitoring is mandatory
Lithium can accumulate to toxic levels in what sodium level... - Correct answer LOW
SODIUM. edu patients to maintain normal sodium intake
Diuretics and lithium - Correct answer these promote sodium loss and can increase
r/f lithium toxicity
NSAIDs and lithium - Correct answer increase lithium levels by 60%
NSAIDs to prescribe when on lithium if necessary - Correct answer aspirin or sulindac
bc they do not increase levels
,Lithium drug interactions - Correct answer diruetics, NSAIDs and anticholinergics
Anticholinergics and lithium - Correct answer cause urinary hesitancy + lithium
induced polyuria which can cause discomfort. AVOID antihistamines, phenothiazine,
antipsychotics and TCAs
Lithium level monitoring - Correct answer measure levels every 2-3 days during initial
therapy and every 3-6 months during maintenance. Serum levels checked 5 days after
any dosage change and 6 months thereafter
LIthium can be toxic to what other organs - Correct answer renal and thyroid. Check
renal/thyroid function every 6 months
SSRIs for MDD - Correct answer fluoxetine, citalopram, escitalopram, fluvoxamine,
paroxetine and sertraline
, Adverse effects of Venlafaxine - Correct answer nausea, HA, anorexia, nervousness,
sweating, somnolence, insomnia, dose related sustained diastolic HTN, mydriasis,
sexual dysfunction.
Venlafaxine drug interaction - Correct answer combo with MAOI is contraindicated.
(this drug is an SNRI)
MAOI adverse effects - Correct answer hypertensive crisis triggered by foods
containing tyramine.
s/s hypertensive crisis - Correct answer HA, tachycardia, palpitations, N/V, sweating
Foods containing tyramine - Correct answer strong aged cheese, cured meats with
salt or nitrate, dry summer sausages, pepperoni, sausage, avocado, figs, yeast extract,
chianti wine, shrimp paste and soy sauce
Pt appropriate for MAOI - Correct answer patients who do NOT respond well to first
line drugs (SSRIs)