NR 566 week 6 (Latest )
Advanced Pharmacology for Care of the
Family Questions & Answers {Grade A}
100% Correct – Chamberlain
What are patients pre-medicated with before administering apomorphine (Apokyn)? -
Correct answer An antiemetic to prevent n/v
Patients should be educated on dopamine dysregulation syndrome (DDS), which
manifests as - Correct answer Drug-seeking and impulse control disorders (ICDs)
such as gambling or compulsive spending
Selegiline ODT (Zelapar), an orally disintegrating tablet, helps - Correct answer
Insomnia
*Helps avoid first-pass metabolism to improve the bioavailability and decrease serum
concentrations of its amphetamine-like metabolite that causes insomnia
,What may occur in patients using PD medications with opioid analgesics,
antidepressants, and other serotonergic agents, or sympathomimetic amines (cold and
weight loss products)? - Correct answer Serotonin syndrome and hypertensive crisis
What is used in patients who do not tolerate or respond to entacapone (Comtan)? -
Correct answer Tolcapone (Tasmar)
*Only time this med is used
Why is tolcapone not used much? - Correct answer Hepatotoxicity
*Serum function tests should be monitored
A decrease in the levodopa dose can improve - Correct answer Dyskinesias
T or F: Dopamine agonists are the most effective medications for Parkinson's Disease -
Correct answer False
,*Levodopa
Combining _______ medications with levodopa in early treatment may delay motor
complications - Correct answer MAO-B inhibitors
Patients should be educated on dopamine dysregulation syndrome (DDS) which can
manifest as - Correct answer Impulse control disorder
What is the therapeutic goal for Helen and others with Parkinson's Disease (PD)? -
Correct answer Symptom management
Helen's family asks why marked symptom improvement is not seen since she was
started on three medications for PD at the time of diagnosis. Which of the following
education points will help Helen's family understand the pharmacological approach to
symptom management in PD? - Correct answer Medications increase the level of
dopamine and decrease the level of acetylcholine in CNS responses can take several
months to occur
, Helen's family asks why she is receiving the combination drug, levodopa/carbidopa,
and not just levodopa. Which of the following education points will help Helen's family
understand the desired effects of carbidopa in the combined levodopa/carbidopa
therapy? - Correct answer Carbidopa reduces cardiovascular responses to levodopa
*Carb reduced card
*Also reduces n/v
Helen and her family have heard of other medications that are used to treat PD and
inquire if they may help control Helen's symptoms. Which of the following medications
may be used for symptom management in PD? - Correct answer Donepezil
*Donepezil may be used for symptom management in PD. Dementia occurs in 40% of
PD patients. AAN guidelines recommend treatment with two drugs: donepezil and
rivastigmine. Both drugs are cholinesterase inhibitors developed for Alzheimer's
disease
Advanced Pharmacology for Care of the
Family Questions & Answers {Grade A}
100% Correct – Chamberlain
What are patients pre-medicated with before administering apomorphine (Apokyn)? -
Correct answer An antiemetic to prevent n/v
Patients should be educated on dopamine dysregulation syndrome (DDS), which
manifests as - Correct answer Drug-seeking and impulse control disorders (ICDs)
such as gambling or compulsive spending
Selegiline ODT (Zelapar), an orally disintegrating tablet, helps - Correct answer
Insomnia
*Helps avoid first-pass metabolism to improve the bioavailability and decrease serum
concentrations of its amphetamine-like metabolite that causes insomnia
,What may occur in patients using PD medications with opioid analgesics,
antidepressants, and other serotonergic agents, or sympathomimetic amines (cold and
weight loss products)? - Correct answer Serotonin syndrome and hypertensive crisis
What is used in patients who do not tolerate or respond to entacapone (Comtan)? -
Correct answer Tolcapone (Tasmar)
*Only time this med is used
Why is tolcapone not used much? - Correct answer Hepatotoxicity
*Serum function tests should be monitored
A decrease in the levodopa dose can improve - Correct answer Dyskinesias
T or F: Dopamine agonists are the most effective medications for Parkinson's Disease -
Correct answer False
,*Levodopa
Combining _______ medications with levodopa in early treatment may delay motor
complications - Correct answer MAO-B inhibitors
Patients should be educated on dopamine dysregulation syndrome (DDS) which can
manifest as - Correct answer Impulse control disorder
What is the therapeutic goal for Helen and others with Parkinson's Disease (PD)? -
Correct answer Symptom management
Helen's family asks why marked symptom improvement is not seen since she was
started on three medications for PD at the time of diagnosis. Which of the following
education points will help Helen's family understand the pharmacological approach to
symptom management in PD? - Correct answer Medications increase the level of
dopamine and decrease the level of acetylcholine in CNS responses can take several
months to occur
, Helen's family asks why she is receiving the combination drug, levodopa/carbidopa,
and not just levodopa. Which of the following education points will help Helen's family
understand the desired effects of carbidopa in the combined levodopa/carbidopa
therapy? - Correct answer Carbidopa reduces cardiovascular responses to levodopa
*Carb reduced card
*Also reduces n/v
Helen and her family have heard of other medications that are used to treat PD and
inquire if they may help control Helen's symptoms. Which of the following medications
may be used for symptom management in PD? - Correct answer Donepezil
*Donepezil may be used for symptom management in PD. Dementia occurs in 40% of
PD patients. AAN guidelines recommend treatment with two drugs: donepezil and
rivastigmine. Both drugs are cholinesterase inhibitors developed for Alzheimer's
disease
