Update) Nurse Practitioners in Primary
Care I Questions and Verified Answers
100% Correct {Grade A} – Wilkes
where is the mycolic aicd in mycobacterium cell membrane? - Correct answer NOPE
the cell wall
PZA: cell _____
INH: cell _____
EMB: cell ____ - Correct answer cell membrane- PZA
cell wall synthesis inhibitor- INH, glycolic acid
EMB-- cell wall, arabinoglycan
Which Hep C genotype is the most common - Correct answer Genotype 1
#1 risk factor for Hep C - Correct answer IV drug use
,When is majority of damage to the liver by Hep C occur - Correct answer 10-40 years
out
Liver cirrohsis stage
3% go to cancer
T/F Most Hep C are symptomatic in the acute phase - Correct answer FALSE only 10%
MOSTLY asymptomiatc
Like HIV, HCV is chornic with no cure - Correct answer FALSE!!!! Goal is cure
Systematic Approach for Selection of Antimicrobials - Correct answer Confirm the
presence of infection
Identify the pathogen
Select empiric therapy considering every infected site
Monitor therapeutic response
Hallmark for ID? - Correct answer FEVER
Controlled elevation of body temperature above normal range
,Temp for fever - Correct answer > 37°C, 98.6°F
Consider APAP/NSAID mask
and drugs causing fever
How do differential WBC change with infection - Correct answer Total WBC over 10,000
Increased NEUtrophils
DECREAsed lymphocytes
At least ___ of the 4 following signs and symptoms must be present for a patient to
meet "SIRS" criteria - Correct answer TWO
Temperature >38°C or <36°C
Heart rate >90 beats per minute
WBC >12,000 or <4,000 or >10% bands
Respiratory rate >20 breaths per minute
, Confirming Sepsis - Correct answer Sepsis: life-threatening ***organ dysfunction***
caused by a dysregulated host response to infection
Empiric therapy - Correct answer Best guess at causative organism and susceptibility
No culture and susceptibility results available
Directed at organisms that are known to cause the infection
Definitive therapy - Correct answer Choosing agent after culture and susceptibility
reports available
Choose antimicrobial of choice for infection if it is susceptible and there are no
contraindications
Selection of empiric therapy HOST factors - Correct answer Site of infection
**Drug allergies**
**Age** -> ADR, organ f(x), etiology
Renal and hepatic function
Concomitant drug therapy
Concomitant disease states- CF (Pseudomonas, diabetics, infection)