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2026 TEST BANK| ACTUAL EXAM QUESTIONS
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Question 1
A patient with chronic kidney disease develops anemia primarily due to which
pathophysiologic mechanism?
A. Increased red blood cell destruction
B. Decreased erythropoietin production
C. Iron malabsorption in the intestine
D. Bone marrow suppression from uremic toxins
Correct Answer: B
Rationale: Diseased kidneys produce less erythropoietin, leading to decreased red
blood cell production and normocytic anemia.
Question 2
,Which electrolyte abnormality is most likely to occur in untreated diabetic
ketoacidosis (DKA)?
A. Hypernatremia
B. Hypocalcemia
C. Hyperkalemia
D. Hypophosphatemia
Correct Answer: C
Rationale: Insulin deficiency and acidosis cause potassium to shift from cells into
the bloodstream, resulting in hyperkalemia despite total body potassium depletion.
Question 3
Atherosclerosis begins with which initial pathological change?
A. Smooth muscle cell proliferation
B. Lipid accumulation in macrophages
C. Endothelial injury and dysfunction
D. Fibrous plaque formation
Correct Answer: C
,Rationale: Endothelial injury increases permeability to lipids and adhesion of
inflammatory cells, initiating plaque development.
D. Hypophosphatemia
Correct Answer: C
Rationale: Insulin deficiency and acidosis cause potassium to shift from cells into
the bloodstream, resulting in hyperkalemia despite total body potassium depletion.
Question 3
Atherosclerosis begins with which initial pathological change?
A. Smooth muscle cell proliferation
B. Lipid accumulation in macrophages
C. Endothelial injury and dysfunction
D. Fibrous plaque formation
Correct Answer: C
, Rationale: Endothelial injury increases permeability to lipids and adhesion of
inflammatory cells, initiating plaque development.
Question 4
A patient presents with fever, hypotension and tachycardia following a severe
infection. Which mechanism best explains the hypotension seen in septic shock?
A. Decreased cardiac output
B. Systemic vasodilation from inflammatory mediators
C. Reduced blood volume from hemorrhage
D. Increased blood viscosity
Correct Answer: B
Rationale: Cytokines and nitric oxide cause widespread vasodilation and increased
capillary permeability, leading to hypotension.
Question 5