NUR 378 Exam 1 | Lehne's Pharmacology for Nursing Care 2026 |
Questions & Verified Answers | Latest Update | Graded A+
1. What term describes the degree of stretching of the ventricular muscles
before contraction?
Afterload
Cardiac output
Stroke volume
Preload
2. Describe the significance of monitoring platelet count during heparin
therapy.
Monitoring platelet count is crucial to detect heparin-induced
thrombocytopenia (HIT).
Platelet count is not relevant during heparin therapy.
Platelet count is monitored to assess liver function.
Monitoring platelet count helps in determining the dosage of warfarin.
3. Which parameter would you use to the follow up the effectiveness of
anticoagulant treatment with heparin ?
Fibrinogen
Prothrombin time (PT)
Platelet count and activity
Activated partial thromboplastin time (aPTT)
4. What enzyme do PPIs inhibit that affects the efficacy of clopidogrel?
, CYP2C19
CYP3A4
CYP1A2
CYP2D6
5. Describe the potential risks of warfarin therapy during pregnancy.
Warfarin can cause fetal hemorrhaging during pregnancy.
Warfarin only affects the mother, not the fetus.
Warfarin has no known effects on pregnancy.
Warfarin is safe for use in all trimesters of pregnancy.
6. Describe the significance of Sodium Nitroprusside in the management of
hypertensive emergencies.
Sodium Nitroprusside is significant because it provides rapid blood
pressure reduction in hypertensive emergencies.
Sodium Nitroprusside has no adverse effects when used
intravenously.
Sodium Nitroprusside is used primarily for chronic hypertension
management.
Sodium Nitroprusside is only effective when administered orally.
7. A patient on anticoagulant therapy presents with a sudden drop in platelet
count. What should be the immediate nursing action based on the monitoring
parameters?
Notify the healthcare provider and assess for signs of bleeding.
Increase the dosage of the anticoagulant medication.
, Continue the anticoagulant therapy without changes.
Perform a routine check of the patient's vital signs.
8. What is a key advantage of Low Molecular Weight Heparins (LMWHs) over
Unfractionated Heparin?
LMWHs inhibit both factor Xa and thrombin equally
LMWHs are more selective for factor Xa and more stable
LMWHs are less stable and require more frequent dosing
LMWHs have a longer duration of action
9. Describe how ACE inhibitors contribute to the management of heart failure
symptoms.
ACE inhibitors primarily increase heart rate, which helps pump more
blood.
ACE inhibitors primarily act to increase fluid retention in the body.
ACE inhibitors help manage heart failure symptoms by causing
arterial and venous dilation, which reduces the workload on the
heart and improves blood flow to the kidneys.
ACE inhibitors block calcium channels to improve heart muscle
contraction.
10. A 70-year-old patient with diabetes and a history of heart failure is
prescribed an antihypertensive medication. Which patient-specific factor
should be prioritized in the selection of their treatment?
Age
Lifestyle choices
Comorbidities
, Medication tolerance
11. What is the primary action of diuretics in the treatment of heart failure?
Enhancing cardiac contractility
Reducing heart rate
Increasing blood pressure
Promoting urine production
12. If a patient is prescribed both a PPI and clopidogrel for cardiovascular
management, what clinical consideration should a healthcare provider keep
in mind?
The potential for reduced antiplatelet efficacy of clopidogrel due
to PPI use.
The PPI will enhance the effects of clopidogrel, making it more
effective.
The PPI will have no impact on the patient's cardiovascular treatment.
The PPI will increase the risk of bleeding associated with clopidogrel.
13. Describe how patient-specific factors can impact the choice of
antihypertensive medications.
Patient-specific factors are irrelevant to medication selection and do
not influence treatment outcomes.
Patient-specific factors are only considered in emergency situations,
not in routine care.
Patient-specific factors can affect both the effectiveness and safety
of antihypertensive medications, leading to tailored treatment
plans.
Questions & Verified Answers | Latest Update | Graded A+
1. What term describes the degree of stretching of the ventricular muscles
before contraction?
Afterload
Cardiac output
Stroke volume
Preload
2. Describe the significance of monitoring platelet count during heparin
therapy.
Monitoring platelet count is crucial to detect heparin-induced
thrombocytopenia (HIT).
Platelet count is not relevant during heparin therapy.
Platelet count is monitored to assess liver function.
Monitoring platelet count helps in determining the dosage of warfarin.
3. Which parameter would you use to the follow up the effectiveness of
anticoagulant treatment with heparin ?
Fibrinogen
Prothrombin time (PT)
Platelet count and activity
Activated partial thromboplastin time (aPTT)
4. What enzyme do PPIs inhibit that affects the efficacy of clopidogrel?
, CYP2C19
CYP3A4
CYP1A2
CYP2D6
5. Describe the potential risks of warfarin therapy during pregnancy.
Warfarin can cause fetal hemorrhaging during pregnancy.
Warfarin only affects the mother, not the fetus.
Warfarin has no known effects on pregnancy.
Warfarin is safe for use in all trimesters of pregnancy.
6. Describe the significance of Sodium Nitroprusside in the management of
hypertensive emergencies.
Sodium Nitroprusside is significant because it provides rapid blood
pressure reduction in hypertensive emergencies.
Sodium Nitroprusside has no adverse effects when used
intravenously.
Sodium Nitroprusside is used primarily for chronic hypertension
management.
Sodium Nitroprusside is only effective when administered orally.
7. A patient on anticoagulant therapy presents with a sudden drop in platelet
count. What should be the immediate nursing action based on the monitoring
parameters?
Notify the healthcare provider and assess for signs of bleeding.
Increase the dosage of the anticoagulant medication.
, Continue the anticoagulant therapy without changes.
Perform a routine check of the patient's vital signs.
8. What is a key advantage of Low Molecular Weight Heparins (LMWHs) over
Unfractionated Heparin?
LMWHs inhibit both factor Xa and thrombin equally
LMWHs are more selective for factor Xa and more stable
LMWHs are less stable and require more frequent dosing
LMWHs have a longer duration of action
9. Describe how ACE inhibitors contribute to the management of heart failure
symptoms.
ACE inhibitors primarily increase heart rate, which helps pump more
blood.
ACE inhibitors primarily act to increase fluid retention in the body.
ACE inhibitors help manage heart failure symptoms by causing
arterial and venous dilation, which reduces the workload on the
heart and improves blood flow to the kidneys.
ACE inhibitors block calcium channels to improve heart muscle
contraction.
10. A 70-year-old patient with diabetes and a history of heart failure is
prescribed an antihypertensive medication. Which patient-specific factor
should be prioritized in the selection of their treatment?
Age
Lifestyle choices
Comorbidities
, Medication tolerance
11. What is the primary action of diuretics in the treatment of heart failure?
Enhancing cardiac contractility
Reducing heart rate
Increasing blood pressure
Promoting urine production
12. If a patient is prescribed both a PPI and clopidogrel for cardiovascular
management, what clinical consideration should a healthcare provider keep
in mind?
The potential for reduced antiplatelet efficacy of clopidogrel due
to PPI use.
The PPI will enhance the effects of clopidogrel, making it more
effective.
The PPI will have no impact on the patient's cardiovascular treatment.
The PPI will increase the risk of bleeding associated with clopidogrel.
13. Describe how patient-specific factors can impact the choice of
antihypertensive medications.
Patient-specific factors are irrelevant to medication selection and do
not influence treatment outcomes.
Patient-specific factors are only considered in emergency situations,
not in routine care.
Patient-specific factors can affect both the effectiveness and safety
of antihypertensive medications, leading to tailored treatment
plans.
