Test Bank Lehne's Pharmacotherapeutics For Advanced
Practice Nurses And Physician 2nd Edition By Laura,
Jacqueline
developed in infants, caution must be used when administering CNS drugs. Lipid-soluble drugs
may be excreted in breast milk if the mother is taking them, but breastfeeding does not affect
medications given directly to the infant. Oral medications may be given safely to infants as long
as they are awake and can swallow the drug.DIF: Cognitive Level: ComprehensionREF: "pp.
20,22,24"TOP: Nursing Process: Assessment MSC: NCLEX Client Needs Category: Physiologic
Integrity: Reduction of Risk Potential
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Providers,2nd Ed.
Chapter 5: Adverse Drug Reactions and Medication Errors
Test Bank
Multiple Choice
35. A nursing student is preparing to give a medication that has a boxed warning. The student asks
the nurse what this means. What will the nurse explain about boxed warnings?
a. They indicate that a drug should not be given except in life-threatening circumstances.
b. They provide detailed information about the adverse effects of the drug.
c. They alert prescribers to measures to mitigate potential harm from side effects.
d. They provide information about antidotes in the event that toxicity occurs.
ANS: C
Boxed warnings (also known as black box warnings) are used to alert providers to potential side
effects and to ways to prevent or reduce harm from these side effects. A boxed warning is placed
on anydrug that, although useful, has serious side effects; this is a way to keep drugs onthe market
while protecting patients. Many of these drugs are used in situations that are not life-threatening.
The boxed warning provides a concise summary and not a detailed explanation of drug side effects.
The boxed warning does not include antidotes to toxicity.DIF: Cognitive Level: AnalysisREF: p.
45TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic
Integrity: Reduction of Risk Potential
36. A nurse is preparing to administer a drug. Upon reading the medication guide, the nurse notes
that the drug has been linked to symptoms of Parkinson disease in some patients. What will
the nurse do?
a. Ask the patient to report these symptoms, which are known to be teratogenic effects.
b. Observe the patient closely for such symptoms and prepare to treat them if needed.
c. Request an order to evaluate the patient’s genetic predisposition to this effect.
d. Warn the patient about these effects and provide reassurance that this is expected.
ANS: B
A drug that causes disease-like symptoms is known to be iatrogenic. Nurses should be prepared
for this possibility and be prepared to withdraw the drug if necessaryand treat the symptoms. Such
, Test Bank Lehne's Pharmacotherapeutics For Advanced
Practice Nurses And Physician 2nd Edition By Laura,
Jacqueline
effects are not teratogenic, since teratogenic effects affect the fetus. Patients with a genetic
predisposition to respond differently to drugs are known to have idiosyncratic effects. Iatrogenic
effects, even when known, are not typically expected side effects.DIF: Cognitive Level:
ApplicationREF: pp. 41-42TOP: Nursing Process: Diagnosis MSC: NCLEX Client Needs
Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
37. Which patients are at increased risk for adverse drug events?
Select all that apply.
a. A 2-month-old infant taking a medication for gastroesophageal reflux disease
b. A 23-year-old female taking an antibiotic for the first time
c. A 40-year-old male who is intubated in the intensive care unit and taking antibiotics and
cardiac medications
d. A 7-year-old female receiving insulin for diabetes
e. An 80-year-old male taking medications for COPD
ANS: A , C , E
Patients at increased risk for adverse drug events include the very young, the very old, and those
who have serious illnesses. Females, children, and young adults taking single medications do not
have increased risk for adverse events.DIF: Cognitive Level: AnalysisREF: "pp. 42,46"TOP:
Nursing Process: Assessment MSC: NCLEX Client Needs Category: Physiologic Integrity:
Reduction of Risk Potential
38. A nurse provides teaching to a patient who will begin taking a drug with a known risk of
hepatotoxicity. Which statement by the patient indicates a need for further teaching?
a. “I should avoid taking acetaminophen while taking this drug.”
b. “I will need periodic evaluation of aspartate aminotransferase and alanine aminotransferase
levels.”
c. “If I experience nausea, vomiting, or abdominal pain, I should call my provider.”
d. “Routine testing and early detection of problems will prevent liver failure.”
ANS: D
Drug-induced liver injury can progress from undetectable to advanced between routine tests;
therefore, routine testing does not always prevent liver failure. Patients taking known hepatotoxic
drugs should avoid other drugs, such as acetaminophen, that can cause liver damage. Aspartate
aminotransferase (AST) and alanine aminotransferase (ALT) are liver enzymes that are routinely
monitored when a patient is taking hepatotoxic drugs. Nausea, vomiting, and abdominal pain are
signs of liver injury and should be reported.DIF: Cognitive Level: ApplicationREF: p. 44TOP:
Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity:
Reduction of Risk Potential
Practice Nurses And Physician 2nd Edition By Laura,
Jacqueline
developed in infants, caution must be used when administering CNS drugs. Lipid-soluble drugs
may be excreted in breast milk if the mother is taking them, but breastfeeding does not affect
medications given directly to the infant. Oral medications may be given safely to infants as long
as they are awake and can swallow the drug.DIF: Cognitive Level: ComprehensionREF: "pp.
20,22,24"TOP: Nursing Process: Assessment MSC: NCLEX Client Needs Category: Physiologic
Integrity: Reduction of Risk Potential
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Providers,2nd Ed.
Chapter 5: Adverse Drug Reactions and Medication Errors
Test Bank
Multiple Choice
35. A nursing student is preparing to give a medication that has a boxed warning. The student asks
the nurse what this means. What will the nurse explain about boxed warnings?
a. They indicate that a drug should not be given except in life-threatening circumstances.
b. They provide detailed information about the adverse effects of the drug.
c. They alert prescribers to measures to mitigate potential harm from side effects.
d. They provide information about antidotes in the event that toxicity occurs.
ANS: C
Boxed warnings (also known as black box warnings) are used to alert providers to potential side
effects and to ways to prevent or reduce harm from these side effects. A boxed warning is placed
on anydrug that, although useful, has serious side effects; this is a way to keep drugs onthe market
while protecting patients. Many of these drugs are used in situations that are not life-threatening.
The boxed warning provides a concise summary and not a detailed explanation of drug side effects.
The boxed warning does not include antidotes to toxicity.DIF: Cognitive Level: AnalysisREF: p.
45TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic
Integrity: Reduction of Risk Potential
36. A nurse is preparing to administer a drug. Upon reading the medication guide, the nurse notes
that the drug has been linked to symptoms of Parkinson disease in some patients. What will
the nurse do?
a. Ask the patient to report these symptoms, which are known to be teratogenic effects.
b. Observe the patient closely for such symptoms and prepare to treat them if needed.
c. Request an order to evaluate the patient’s genetic predisposition to this effect.
d. Warn the patient about these effects and provide reassurance that this is expected.
ANS: B
A drug that causes disease-like symptoms is known to be iatrogenic. Nurses should be prepared
for this possibility and be prepared to withdraw the drug if necessaryand treat the symptoms. Such
, Test Bank Lehne's Pharmacotherapeutics For Advanced
Practice Nurses And Physician 2nd Edition By Laura,
Jacqueline
effects are not teratogenic, since teratogenic effects affect the fetus. Patients with a genetic
predisposition to respond differently to drugs are known to have idiosyncratic effects. Iatrogenic
effects, even when known, are not typically expected side effects.DIF: Cognitive Level:
ApplicationREF: pp. 41-42TOP: Nursing Process: Diagnosis MSC: NCLEX Client Needs
Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
37. Which patients are at increased risk for adverse drug events?
Select all that apply.
a. A 2-month-old infant taking a medication for gastroesophageal reflux disease
b. A 23-year-old female taking an antibiotic for the first time
c. A 40-year-old male who is intubated in the intensive care unit and taking antibiotics and
cardiac medications
d. A 7-year-old female receiving insulin for diabetes
e. An 80-year-old male taking medications for COPD
ANS: A , C , E
Patients at increased risk for adverse drug events include the very young, the very old, and those
who have serious illnesses. Females, children, and young adults taking single medications do not
have increased risk for adverse events.DIF: Cognitive Level: AnalysisREF: "pp. 42,46"TOP:
Nursing Process: Assessment MSC: NCLEX Client Needs Category: Physiologic Integrity:
Reduction of Risk Potential
38. A nurse provides teaching to a patient who will begin taking a drug with a known risk of
hepatotoxicity. Which statement by the patient indicates a need for further teaching?
a. “I should avoid taking acetaminophen while taking this drug.”
b. “I will need periodic evaluation of aspartate aminotransferase and alanine aminotransferase
levels.”
c. “If I experience nausea, vomiting, or abdominal pain, I should call my provider.”
d. “Routine testing and early detection of problems will prevent liver failure.”
ANS: D
Drug-induced liver injury can progress from undetectable to advanced between routine tests;
therefore, routine testing does not always prevent liver failure. Patients taking known hepatotoxic
drugs should avoid other drugs, such as acetaminophen, that can cause liver damage. Aspartate
aminotransferase (AST) and alanine aminotransferase (ALT) are liver enzymes that are routinely
monitored when a patient is taking hepatotoxic drugs. Nausea, vomiting, and abdominal pain are
signs of liver injury and should be reported.DIF: Cognitive Level: ApplicationREF: p. 44TOP:
Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity:
Reduction of Risk Potential
