GN 311 EXAM -3 QUESTIONS WITH VERIFIED ANSWERS

GN 311 EXAM #3 QUESTIONS WITH VERIFIED
ANSWERS

Transversion - Answers - An alteration in the DNA from an AT base pair to a CG base
pair is called a ___.

Transition - Answers - An alteration in the DNA from an CG base pair to a TA base pair
is called a ___.

Proofreading repair; base excision repair - Answers - Which repair mechanism(s)
involve(s) the removal of a single nucleotide?

Frameshift - Answers - An insertion of a single base pair in the DNA strand is called a
___ mutation.

Nucleotide excision repair; mismatch repair - Answers - Which repair mechanism(s)
involve(s) the removal of several nucleotides?

Positive Inducible; negative inducible - Answers - The type(s) of prokaryotic regulation
where: transcription occurs with high effector levels.

Only functional permease is produced. Functional beta-galactosidase is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
ABSENT and the lac operon genotype is:
I-P+O+Z-Y+

Functional beta-galactosidase is NOT produced. Functional permease is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
ABSENT and the lac operon genotype is:
I+P-O+Z+Y+

Functional beta-galactosidase is NOT produced. Functional permease is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
ABSENT and the lac operon genotype is:
I+P+O+Z-Y+

Functional beta-galactosidase is NOT produced. Functional permease is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
PRESENT and the lac operon genotype is:
IsP+O+Z-Y+

Functional beta-galactosidase and functional permease are produced - Answers - Will
functional permease and beta-galactosidase be produced if lactose is ABSENT and the
lac operon genotype is:

, IsP-O+Z-Y-/I-P+OcZ+Y+

Only functional permease is produced. Functional beta-galactosidase is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
PRESENT and the lac operon genotype is:
I+P+OcZ-Y+/I-P+O+Z-Y+

Only functional beta-galactosidase is produced. Functional permease is NOT produced
- Answers - Will functional permease and beta-galactosidase be produced if lactose is
PRESENT and the lac operon genotype is:
I+P+O+Z+Y-/IsP+OcZ+Y-

Cis-acting, variable position, variable orientation - Answers - Which set of terms applies
to enhancers as they are associated with eukaryotic gene regulation?

Phosphate groups; methyl groups; acetyl groups; amino groups - Answers - Histone
modifications during chromatin remodeling can include additions of ____, ____, and
____ but not ____

Alkaptonuria was one of the first disease phenotypes correlated with a genotype. It is
characterized by absense of homogentisate oxidase activity. - Answers - Was the
significance of Alkaptonuria?

Garrod - Answers - Scientist who conducted experiments on Alkaptonuria and diet's
effect on it

Auxotroph - Answers - Requires some chemical for growth; won't grow on minimal
media because unable to synthesize a lot of necessary nutrients

Occur in nonreproductive cells and are passed to new cells through mitosis (some of
the cells in organism affected) - Answers - Somatic mutations

Occur in reproductive cells and are passed down to half of the members of the next
generation, who will carry the mutation in all of their cells - Answers - Germ-line
mutations

Cell produces protein that is not normally present; either new gene product or gene
product in new location/at an inappropriate time during development - Answers - Gain of
function protein mutation

Results in substitution of 1 base for another - Answers - Point mutation

Purine to purine or pyrimidine to pyrimidine change; A to G, C to T, etc. - Answers -
Transition point mutation definition; what base change to what?