PRITE PSYCHOPHARMACOLOGY SOLVED
QUESTIONS AND CORRECT ANSWERS FULL
STUDY MATERIAL
●● anterior cerebral artery - top is A2, bottom is A1
A1 - supplies internal capsule, limbic system; may have minimal Sx d/t
collateral flow from ACoA
A2 - contralateral paresis and anesthesia of lower limb
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● middle cerebral artery - M1 is proximal to the early cortical branches
and M2 is distal to the early cortical branches
either segment - contralateral hemiplegia, hemianesthesia, homonymous
hemianopia
Dominent hemisphere = Dysarthria (actually aphasia)
Nondominent = Neglect
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● posterior cerebral artery - P1 is proximal to PCoA, P2 is distal to
PCoA.
,P1 Syndrome - affects midbrain, thalamus, hypothalamus. Claude
syndrome - third nerve palsy and contralateral ataxia (red nucleus of
midbrain); Weber's syndrome - third nerve palsy and hemiplegia
(cerebral peduncle)
P2 Syndrome - affects medial temporal and occipital lobes. Contralateral
homonymous hemianopia with macular sparing.
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● basilar artery
"Locked in" syndrome - quadreplegia, cranial nerve signs, preserved
consciousness (lower midbrain)
Answer: Name this artery. Name the stroke symptoms associated with
occlusion of this artery.
●● pontine arteries
Answer: #11 - name the arteries
●● superior cerebellar artery
Answer: #10 - name the artery
●● anterior inferior cerebellar artery - ipsilateral limb Ataxia,
contralateral loss of pain and temperature
,Lateral pontine syndrome (fACIAl): loss of taste, lacrimation, salivation,
hyperaucusis ipsilateral; ipsilateral paralysis of face
Answer: #14 - name the artery. Name the stroke symptoms associated
with occlusion of this artery.
●● posterior inferior cerebellar artery - lateral medullary / Wallenberg
syndrome
PIC - Pain and temperature, Ipsilateral loss on face, Contralateral loss on
body. Horner syndrome (small pupil, ptosis, decreased sweating; "pH =
PICA/Horner").
Answer: #16 - name the artery. Name the stroke symptoms associated
with occlusion of this artery.
●● vertebral artery
Answer: Name this artery.
●● posterior limb of the internal capsule
Answer: A lacunar stroke of what area would cause a pure motor stroke,
or lower extremity ataxia?
●● ventroposterolateral nucleus of thalamus
Answer: A lacunar stroke of what area would cause a pure sensory
stroke?
, ●● basilar pons
Answer: A lacunar stroke of what area would cause dysarthria/clumsy
hand syndrome?
●● Mechanism of action: NRT binding induces Na influx or Cl influx
Outcome effect: excitation or inhibition of membrane
Receptor / NRT: nicotinic AChR (ACh), NMDA (glutamate), 5HT-3
(serotonin), GABA-A (GABA)
# transmembrane receptors: 4 transmembrane receptors on each of 5
subunits within one receptor
Answer: For the ionotropic receptor subtype, give the mechanism of
action, outcome effect, example receptor/ neurotransmitter pairs within
this subtype, and the number of transmembrane receptor units.
●● Mechanism of action: NRT binding induces physical transformation
of receptor, G protein activation, adenylyl cyclase enzyme activation,
formation of second messenger (cAMP or IP3), activation of protein
kinase, phosphorylation of transcription factor
Outcome effect: gene transcription
Receptor / NRT: muscarinic AChR (ACh), alpha, beta (NE, E), mu
(endorphins, enkaphalins), 5HT other than 3 (serotonin), D1, D2 (DA)
# transmembrane receptors: 7
Answer: For the G-protein coupled receptor subtype, give the
mechanism of action, outcome effect, example receptor/
QUESTIONS AND CORRECT ANSWERS FULL
STUDY MATERIAL
●● anterior cerebral artery - top is A2, bottom is A1
A1 - supplies internal capsule, limbic system; may have minimal Sx d/t
collateral flow from ACoA
A2 - contralateral paresis and anesthesia of lower limb
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● middle cerebral artery - M1 is proximal to the early cortical branches
and M2 is distal to the early cortical branches
either segment - contralateral hemiplegia, hemianesthesia, homonymous
hemianopia
Dominent hemisphere = Dysarthria (actually aphasia)
Nondominent = Neglect
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● posterior cerebral artery - P1 is proximal to PCoA, P2 is distal to
PCoA.
,P1 Syndrome - affects midbrain, thalamus, hypothalamus. Claude
syndrome - third nerve palsy and contralateral ataxia (red nucleus of
midbrain); Weber's syndrome - third nerve palsy and hemiplegia
(cerebral peduncle)
P2 Syndrome - affects medial temporal and occipital lobes. Contralateral
homonymous hemianopia with macular sparing.
Answer: Name this artery and its segments.
Name the stroke symptoms associated with occlusion of each segment.
●● basilar artery
"Locked in" syndrome - quadreplegia, cranial nerve signs, preserved
consciousness (lower midbrain)
Answer: Name this artery. Name the stroke symptoms associated with
occlusion of this artery.
●● pontine arteries
Answer: #11 - name the arteries
●● superior cerebellar artery
Answer: #10 - name the artery
●● anterior inferior cerebellar artery - ipsilateral limb Ataxia,
contralateral loss of pain and temperature
,Lateral pontine syndrome (fACIAl): loss of taste, lacrimation, salivation,
hyperaucusis ipsilateral; ipsilateral paralysis of face
Answer: #14 - name the artery. Name the stroke symptoms associated
with occlusion of this artery.
●● posterior inferior cerebellar artery - lateral medullary / Wallenberg
syndrome
PIC - Pain and temperature, Ipsilateral loss on face, Contralateral loss on
body. Horner syndrome (small pupil, ptosis, decreased sweating; "pH =
PICA/Horner").
Answer: #16 - name the artery. Name the stroke symptoms associated
with occlusion of this artery.
●● vertebral artery
Answer: Name this artery.
●● posterior limb of the internal capsule
Answer: A lacunar stroke of what area would cause a pure motor stroke,
or lower extremity ataxia?
●● ventroposterolateral nucleus of thalamus
Answer: A lacunar stroke of what area would cause a pure sensory
stroke?
, ●● basilar pons
Answer: A lacunar stroke of what area would cause dysarthria/clumsy
hand syndrome?
●● Mechanism of action: NRT binding induces Na influx or Cl influx
Outcome effect: excitation or inhibition of membrane
Receptor / NRT: nicotinic AChR (ACh), NMDA (glutamate), 5HT-3
(serotonin), GABA-A (GABA)
# transmembrane receptors: 4 transmembrane receptors on each of 5
subunits within one receptor
Answer: For the ionotropic receptor subtype, give the mechanism of
action, outcome effect, example receptor/ neurotransmitter pairs within
this subtype, and the number of transmembrane receptor units.
●● Mechanism of action: NRT binding induces physical transformation
of receptor, G protein activation, adenylyl cyclase enzyme activation,
formation of second messenger (cAMP or IP3), activation of protein
kinase, phosphorylation of transcription factor
Outcome effect: gene transcription
Receptor / NRT: muscarinic AChR (ACh), alpha, beta (NE, E), mu
(endorphins, enkaphalins), 5HT other than 3 (serotonin), D1, D2 (DA)
# transmembrane receptors: 7
Answer: For the G-protein coupled receptor subtype, give the
mechanism of action, outcome effect, example receptor/
