Rush
Rush - Advanced Pharmacology - NSG 531 - Exam 1
(2026 updated) QUESTIONS AND ANSWERS
(DETAILED & ELABORATED) fully solved
Terms in this set (131)
Druga substance intended for use in the diagnosis, cure,
mitigation, treatment, or prevention of
disease and a substance, other than food,
intended to affect the structure or any
function of the body
T/F most drugs are strong acids orF - most drugs are weak acids or weak bases
strong bases
what are the four things that the1. absorbs it body does to a drug?2.
distributes it (think about it - most drugs don't
have MOA in the stomach or GI tract,
the body distributes to where it acts) 3.
biotransforms or metabolizes it
4. eliminates it
Pharmacokinetics what the body does to the drug
Rush - Advanced Pharmacology - NSG 531 - Exam 1 (2026 updated) QUESTIONS AND
ANSWERS
,Describe absorptiondrugs that are given orally have to get out of the
gut and into circulation in order to do that
the drugs have to pass through cell
membranes this means there has to be
some form of solubility for the drug to pass
through the cell membrane cell
membranes are made of lipids therefore
drugs have to have some form of lipid
solubility
What are cell membranes made of? phsopholipid bilayer
What is the only route of drug thatIV push - because it goes directly into
circulation does not have to pass through the cell membrane?
What are the four mechanisms of1. simple diffusion
transport across the cell membrane?2.
channel-mediated
3. carrier-mediated
4. Active Transport
Simple diffusion - what has to be- drug has to be lipid soluble
true?-there has to be a concentration gradient present
-if a drug is high in fat solubility it is not
going to be very water soluble - these two
properties balance each other out
If a drug is high in lipid solubility andit may meet an aqueous solution and
because it is it is able to be transported by simplenot highly water
soluble it will need to bind to a diffusion, what will happen once itcarrier
protein to be transported throughout the crosses the cell membrane?
circulation
Rush - Advanced Pharmacology - NSG 531 - Exam 1 (2026 updated) QUESTIONS AND ANSWERS
, What are the channels in Channelchannels are two groups of proteins
on each side mediated transportthat create a pore in the cell
membrane
Rush - Advanced Pharmacology - NSG 531 - Exam 1
(2026 updated) QUESTIONS AND ANSWERS
(DETAILED & ELABORATED) fully solved
Terms in this set (131)
Druga substance intended for use in the diagnosis, cure,
mitigation, treatment, or prevention of
disease and a substance, other than food,
intended to affect the structure or any
function of the body
T/F most drugs are strong acids orF - most drugs are weak acids or weak bases
strong bases
what are the four things that the1. absorbs it body does to a drug?2.
distributes it (think about it - most drugs don't
have MOA in the stomach or GI tract,
the body distributes to where it acts) 3.
biotransforms or metabolizes it
4. eliminates it
Pharmacokinetics what the body does to the drug
Rush - Advanced Pharmacology - NSG 531 - Exam 1 (2026 updated) QUESTIONS AND
ANSWERS
,Describe absorptiondrugs that are given orally have to get out of the
gut and into circulation in order to do that
the drugs have to pass through cell
membranes this means there has to be
some form of solubility for the drug to pass
through the cell membrane cell
membranes are made of lipids therefore
drugs have to have some form of lipid
solubility
What are cell membranes made of? phsopholipid bilayer
What is the only route of drug thatIV push - because it goes directly into
circulation does not have to pass through the cell membrane?
What are the four mechanisms of1. simple diffusion
transport across the cell membrane?2.
channel-mediated
3. carrier-mediated
4. Active Transport
Simple diffusion - what has to be- drug has to be lipid soluble
true?-there has to be a concentration gradient present
-if a drug is high in fat solubility it is not
going to be very water soluble - these two
properties balance each other out
If a drug is high in lipid solubility andit may meet an aqueous solution and
because it is it is able to be transported by simplenot highly water
soluble it will need to bind to a diffusion, what will happen once itcarrier
protein to be transported throughout the crosses the cell membrane?
circulation
Rush - Advanced Pharmacology - NSG 531 - Exam 1 (2026 updated) QUESTIONS AND ANSWERS
, What are the channels in Channelchannels are two groups of proteins
on each side mediated transportthat create a pore in the cell
membrane
