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HERBAL SUPPLEMENT REVIEW
St. John’s Wort: Herbal Supplement Review
Kelsi Hayes
Maryville University
Author Note
No conflict of interest.
Correspondence concerning this article should be addressed to Kelsi Hayes, 650
Maryville University Drive, St. Louis, MO 63141. Email:
, 2
HERBAL SUPPLEMENT REVIEW
Abstract
St. John’s wort (Hypericum perforatum) is an herbal supplement widely used to treat mild-to-
moderate depression. St. John’s wort influences serotonin availability through specific enzyme
activations. However, consultation with a healthcare professional is crucial to under the risks and
potential drug-herb interactions that may occur.
Keywords: St. John’s wort, depression, drug-herb interaction, selective serotonin
reuptake inhibitors
HERBAL SUPPLEMENT REVIEW
St. John’s Wort: Herbal Supplement Review
Kelsi Hayes
Maryville University
Author Note
No conflict of interest.
Correspondence concerning this article should be addressed to Kelsi Hayes, 650
Maryville University Drive, St. Louis, MO 63141. Email:
, 2
HERBAL SUPPLEMENT REVIEW
Abstract
St. John’s wort (Hypericum perforatum) is an herbal supplement widely used to treat mild-to-
moderate depression. St. John’s wort influences serotonin availability through specific enzyme
activations. However, consultation with a healthcare professional is crucial to under the risks and
potential drug-herb interactions that may occur.
Keywords: St. John’s wort, depression, drug-herb interaction, selective serotonin
reuptake inhibitors