ASCP BLOOD BANK EXAM| COMPLETE QUESTIONS WITH 100% RATED EXPERT
SOLUTIONS |2026 LATEST UPDATED
1. Results of a serum sample tested against a panel of reagent red cells
gives presumptive evidence of an alloantibody directed against a high
incidence antigen. Further investigation to confirm the specificity should
include which of the following?
A.serum testing against red cells from random donors
B.serum testing against red cells known to lack high incidence antigens
C.serum testing against enzyme treated autologous red cells
D.testing of an eluate prepared from the patient's red cells: B. serum testing
against red cells known to lack high incidence antigens
2. Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused by
which of the following maternal antibodies? A.IgM alloantibodies against
ABO antigens
B.IgG alloantibodies against HLA antigens
,C.IgM alloantibodies against glycoprotein V (GPV) antigens
D.IgG alloantibodies against HPA antigens: D. IgG alloantibodies against HPA
antigens
FNAIT is due to maternal IgG alloantibodies crossing the placenta and
reacting with fetal platelet HPA antigens.
3. The purpose of testing with anti-A,B is to detect:
A.anti-A1
B.anti-A2
C.subgroups of A
D.subgroups of O: Subgroups of A
Ax cells react more strongly with anti-A,B than with anti-A. If anti-A is
nonreactive, Ax cells may be detected with anti-A,B.
4. What increment of platelets in the typical 70-kg human is expected to
result from each single unit of Platelets transfused to a non-HLA-sensitized
recipient?
,A.3,000 - 5,000/µL
B.5,000 - 10,000/µL
C.20,000 - 25,000/µL
D.25,000 - 30,000/µL: B.5,000 - 10,000/µL
One unit of Platelets made from whole blood should cause the platelet count
to increase from 5,000-10,000/µL.
5. All donor blood testing must include:
A.complete Rh phenotyping
B.anti-CMV testing
C.direct antiglobulin test
D.serological test for syphilis: D.serological test
for syphilis 6. A sample gives the following
results:
Cells with Anti A: 3+ Anti B: 4+
Serum with A1: 2+ and B: 0
, Which lectin should be used first to resolve this discrepancy?
A.Ulex europaeus
B.Arachis hypogaea
C.Dolichos biflorus
D.Vicia graminea: C.Dolichos biflorus
Dolichos biflorus plant seed extract forms complexes with N-
acetylgalactosamine. When properly diluted, it can distinguish between A1
donor cells and all other subgroups of A.
7. Transfusion-associated HTLV I/II incidence is low due to the following
laboratory testing:
A.nucleic acid testing for HTLV I/II
B.HTLV I core antibody testing by ELISA
C.HTLV II surface antigen testing by chemiluminescent immunoassay
(ChLIA) D.IgG antibody testing for HTLV I/II by ELISA or ChLIA: D.IgG
antibody testing for HTLV
SOLUTIONS |2026 LATEST UPDATED
1. Results of a serum sample tested against a panel of reagent red cells
gives presumptive evidence of an alloantibody directed against a high
incidence antigen. Further investigation to confirm the specificity should
include which of the following?
A.serum testing against red cells from random donors
B.serum testing against red cells known to lack high incidence antigens
C.serum testing against enzyme treated autologous red cells
D.testing of an eluate prepared from the patient's red cells: B. serum testing
against red cells known to lack high incidence antigens
2. Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused by
which of the following maternal antibodies? A.IgM alloantibodies against
ABO antigens
B.IgG alloantibodies against HLA antigens
,C.IgM alloantibodies against glycoprotein V (GPV) antigens
D.IgG alloantibodies against HPA antigens: D. IgG alloantibodies against HPA
antigens
FNAIT is due to maternal IgG alloantibodies crossing the placenta and
reacting with fetal platelet HPA antigens.
3. The purpose of testing with anti-A,B is to detect:
A.anti-A1
B.anti-A2
C.subgroups of A
D.subgroups of O: Subgroups of A
Ax cells react more strongly with anti-A,B than with anti-A. If anti-A is
nonreactive, Ax cells may be detected with anti-A,B.
4. What increment of platelets in the typical 70-kg human is expected to
result from each single unit of Platelets transfused to a non-HLA-sensitized
recipient?
,A.3,000 - 5,000/µL
B.5,000 - 10,000/µL
C.20,000 - 25,000/µL
D.25,000 - 30,000/µL: B.5,000 - 10,000/µL
One unit of Platelets made from whole blood should cause the platelet count
to increase from 5,000-10,000/µL.
5. All donor blood testing must include:
A.complete Rh phenotyping
B.anti-CMV testing
C.direct antiglobulin test
D.serological test for syphilis: D.serological test
for syphilis 6. A sample gives the following
results:
Cells with Anti A: 3+ Anti B: 4+
Serum with A1: 2+ and B: 0
, Which lectin should be used first to resolve this discrepancy?
A.Ulex europaeus
B.Arachis hypogaea
C.Dolichos biflorus
D.Vicia graminea: C.Dolichos biflorus
Dolichos biflorus plant seed extract forms complexes with N-
acetylgalactosamine. When properly diluted, it can distinguish between A1
donor cells and all other subgroups of A.
7. Transfusion-associated HTLV I/II incidence is low due to the following
laboratory testing:
A.nucleic acid testing for HTLV I/II
B.HTLV I core antibody testing by ELISA
C.HTLV II surface antigen testing by chemiluminescent immunoassay
(ChLIA) D.IgG antibody testing for HTLV I/II by ELISA or ChLIA: D.IgG
antibody testing for HTLV
