Lehne’s Pharmacotherapeutics for Advanced Practice Nurses
and Physician Assistants
Laura D. Rosenthal, and Jacqueline Rosenjack Burchum
3rd Edition
,Question Bank - Lehne’s P ha rmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 3e (Rosenthal, 2025)
TABLE OF CONTENTS
UNIT I: INTRODUCTION UNIT VIII: SUBSTANCE USE DISORDERS UNIT XV: RESPIRATORY TRACT DRUGS
1. Prescriptive Authority 32. Substance Use Disorders I: Basic Considerations 62. Drugs for Asthma and Chronic Obstructive
2. Rational Drug Selection and Prescription Writing 33. Substance Use Disorders II: Alcohol Pulmonary Disease
3. Promoting Positive Outcomes of Drug Therapy 34. Substance Use Disorders III: Nicotine and 63. Drugs for Allergic Rhinitis, Cough, and Colds
Smoking
UNIT II: BASIC PRINCIPLES OF UNIT XVI: GASTROINTESTINAL DRUGS
35. Substance Use Disorders IV: Major Drugs of
PHARMACOLOGY Abuse Other Than Alcohol and Nicotine 64. Drugs for Peptic Ulcer Disease
4. Pharmacokinetics, Pharmacodynamics, and Drug 65. Laxatives
UNIT IX: DRUGS THAT AFFECT THE
Interactions 66. Other Gastrointestinal Drugs
HEART, BLOOD VESSELS, BLOOD, AND
5. Adverse Drug Reactions and Medication Errors
BLOOD VOLUME UNIT XVII: NUTRITION AND
6. Individual Variation in Drug Responses
36. Review of Hemodynamics COMPLEMENTARY THERAPIES
7. Genetic and Genomic Considerations in
Pharmacotherapeutics 37. Diuretics 67. Vitamins
38. Drugs Acting on the Renin-Angiotensin- 68. Drugs for Weight Loss
UNIT III: DRUG THERAPY ACROSS THE Aldosterone System 69. Complementary and Alternative Therapies
LIFE SPAN 39. Calcium Channel Blockers
8. Drug Therapy During Pregnancy and Breast- 40. Vasodilators UNIT XVIII: THERAPY OF INFECTIOUS
Feeding 41. Drugs for Hypertension AND PARASITIC DISEASES
9. Drug Therapy in Pediatric Patients 42. Drugs for Heart Failure 70. Basic Principles of Antimicrobial Therapy
10. Drug Therapy in Geriatric Patients 43. Antidysrhythmic Drugs 71. Drugs That Weaken the Bacterial Cell Wall I:
44. Prophylaxis of Atherosclerotic Cardiovascular Penicillins
UNIT IV: PERIPHERAL NERVOUS SYSTEM
Disease: Drugs That Help Normalize Cholesterol 72. Drugs That Weaken the Bacterial Cell Wall II:
DRUGS
and Triglyceride Levels Other Drugs
11. Basic Principles of Neuropharmacology 45. Drugs for Angina Pectoris 73. Bacteriostatic Inhibitors of Protein Synthesis
12. Physiology of the Peripheral Nervous System 46. Anticoagulant, Antiplatelet, and Thrombolytic 74. Aminoglycosides: Bactericidal Inhibitors of
13. Muscarinic Agonists Drugs Protein Synthesis
14. Muscarinic Antagonists 47. Drugs for Deficiency Anemias 75. Sulfonamides and Trimethoprim
15. Adrenergic Agonists 76. Drug Therapy of Urinary Tract Infections
UNIT X: DRUGS FOR ENDOCRINE
16. Adrenergic Antagonists 77. Drug Therapy for Tuberculosis
DISORDERS
17. Indirect-Acting Antiadrenergic Agents 78. Miscellaneous Antibacterial Drugs
48. Drugs for Diabetes Mellitus 79. Antifungal Agents
UNIT V: CENTRAL NERVOUS SYSTEM 49. Drugs for Thyroid Disorders 80. Antiviral Agents I: Drugs for Non-HIV Viral
DRUGS Infections
UNIT XI: WOMEN'S HEALTH
18. Introduction to Central Nervous System 81. Antiviral Agents II: Drugs for HIV Infection and
Pharmacology 50. Estrogens and Progestins: Basic Pharmacology Related Opportunistic Infections
19. Drugs for Parkinson Disease and Noncontraceptive Applications 82. Drug Therapy of Sexually Transmitted Diseases
20. Drugs for Alzheimer Disease 51. Birth Control 83. Anthelmintics, Antiprotozoal Drugs, and
21. Drugs for Seizure Disorders Ectoparasiticides
UNIT XII: MEN'S HEALTH
22. Drugs for Muscle Spasm and Spasticity
52. Androgens UNIT XIX: CANCER THERAPY
UNIT VI: DRUGS FOR PAIN 53. Drugs for Erectile Dysfunction and Benign 84. Introduction to Immunomodulators
Prostatic Hyperplasia 85. Supportive Care of Patients Receiving Anticancer
23. Local Anesthetics
24. Opioid Analgesics, Opioid Antagonists, and Drugs
UNIT XIII: ANTI-INFLAMMATORY,
Nonopioid Centrally Acting Analgesics ANTIALLERGIC, AND IMMUNOLOGIC 86. Drugs for Cancer Pain
25. Drugs for Headache DRUGS UNIT XX: DRUGS FOR EYES, EARS, AND
UNIT VII: PSYCHOTHERAPEUTIC DRUGS 54. Review of the Immune System SKIN
55. Childhood Immunization 87. Drugs for the Eye
26. Antipsychotic Agents and Their Use in
Schizophrenia 56. Antihistamines 88. Drugs for the Skin
27. Antidepressants 57. Cyclooxygenase Inhibitors: Nonsteroidal Anti- 89. Drugs for the Ear
inflammatory Drugs and Acetaminophen
28. Drugs for Bipolar Disorder
58. Glucocorticoids in Nonendocrine Disorders UNIT XXI: DRUG THERAPY IN ACUTE
29. Sedative-Hypnotic Drugs CARE
30. Management of Anxiety Disorders UNIT XIV: DRUGS FOR BONE AND JOINT
31. Central Nervous System Stimulants and DISORDERS 90. Agents Affecting the Volume and Ion Content of
Attention-Deficit/Hyperactivity Disorder Body Fluids
59. Drug Therapy of Rheumatoid Arthritis 91. Management of ST-Elevation Myocardial
60. Drug Therapy of Gout Infarction
61. Drugs Affecting Calcium Levels and Bone 92. Additional Acute Care Drugs
Mineralization
,Question Bank - Lehne’s P ha rmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 3e (Rosenthal, 2025)
Unit 01: Introduction
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician
Assistants, 3rd Edition
LEHNE’S PHARMACOTHERAPEUTICS FOR
ADVANCED PRACTICE NURSES AND
PHYSICIAN ASSISTANTS
Chapter 1: Prescriptive Authority
Test Bank
Multiple Choice
1. An APRN works in a urology clinic under the supervision of a physician who does not restrict
the types of medications the APRN is allowed to prescribe. State law does not require the
APRN to practice under physician supervision. How would the APRN’s prescriptive
authority be described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
ANS: B
The APRN has independent prescriptive authority because the regulating body does not require
that the APRN work under physician supervision. Full prescriptive authority gives the provider
the right to prescribe independently and without limitation. Limited authority places restrictions
on the types of drugs that can be prescribed.DIF: Cognitive Level: ComprehensionREF: p. 1TOP:
Nursing Process: I MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
and Parenteral Therapies
2. Which factors increase the need for APRNs to have full prescriptive authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician’s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
ANS: A
Implementation of the Affordable Care Act has increased the number of individuals with health
care coverage, and thus the number who have access to health care services. The increase in the
number of patients creates the need for more providers with prescriptive authority. APRNs can
fill this practice gap.DIF: Cognitive Level: ComprehensionREF: p. 2TOP: Nursing Process:
Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
and Parenteral Therapies
3. Which factors could be attributed to limited prescriptive authority for
APRNs? Select all that apply.
, Question Bank - Lehne’s Pharmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 3e (Rosenthal, 2025)
Unit 01: Introduction
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician
Assistants, 3rd Edition
a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
ANS: A , B
Limiting prescriptive authority for APRNs can create barriers to quality, affordable, and
accessible patient care. It may also lead to poor collaboration among providers and higher health
care costs. It would not directly impact patient’s health literacy.DIF: Cognitive Level:
ComprehensionREF:
p. 2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic
Integrity: Pharmacologic and Parenteral Therapies
4. Which aspects support the APRN’s provision for full prescriptive
authority? Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN’s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
e. Limiting provision can decrease health care affordability.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive
Level: ComprehensionREF: pp. 1-2TOP: Nursing Process: Implementation MSC: NCLEX Client
Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
5. Which aspects support the APRN’s provision for full prescriptive
authority? Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN’s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive Level: