GMS 6540 Updated Actual Exam Question
and Answer (2026/2027) | 100% Verified
Answers
• Which drug is active against Gram positive bacteria as well as mycoplasma? -✓✓
Tetracycline
• Which macrolide would be expected to have better patient compliance when
taken orally? -✓✓ Azithromycin
• Which antibiotic may, in some cases, exert its effect inside of human cells? -✓✓
Doxycycline
• An ambulance brings in a patient that is in a non-responsive patient suffering
from sepsis due to a S. aureus infection. You go to administer amoxicillin but
notice that they are wearing a medical bracelet saying that they are allergic to
penicillins. Which drug is the most likely alternative to be used for this patient? -
✓✓ clindamycin
• Which mechanism best describes the cause of gray baby syndrome in the use of
chloramphenicol? -✓✓ The drug is cleared slower from babies than in adults
• What part of the bacterial life cycle is most strongly inhibited by ciprofloxacin? -
✓✓ replication
• In general, do we have more drug options for treating aerobic or anaerobic
bacterial infections? -✓✓ aerobic
• Would isoniazid be expected to increase or decrease the activity of drug-
metabolizing enzymes toward other drugs? -✓✓ decrease
• Two patients that are identical in every way except that one is a slow acetylator
and the other is a fast acetylator of isoniazid are being treated for tuberculosis.
Patient A is receiving 15mg/kg once per week and Patient B is receiving 15mg/kg
three times per week. Which patient is the fast acetylator? -✓✓ Patient B
, • Which bacterial cell function is most directly inhibited by rifampin? -✓✓
Transcription
• What is the primary reason that treatment for mycobacteria infection involves
many drugs taken simultaneously -✓✓ to prevent resistance
• Your physician prescribes you an anti-mycobacterial drug and when you ask how
it works, they say, "I don't know." Assuming the physician is competent, which
drug was likely prescribed? -✓✓ Pyrazinamide
• Does amphotericin B increase or decrease the amount of diffusion that happens
across a fungal cell membrane? -✓✓ increase
• What type of biological molecule does Caspofungin bind to? -✓✓ Protein
• If a 1mg/kg does of amphotericin B kills 25% of present fungus and a 30mg/kg
dose of flucytosine kills 30% of present fungus, what would be a reasonable
amount of fungus to expect to be killed if the two doses are given simultaneously?
-✓✓ 75%
• Which of the following antifungals is available OTC to treat athlete's foot? -✓✓
terbinafine
• Which drug is only used to treat thrush? -✓✓ Nystatin
• What type of molecule is the ultimate target of Flagyl? -✓✓ DNA
• What type of molecule is the ultimate target of chloroquine? -✓✓ Protein
• Which drug is a natural product that can be isolated from the bark of a tree? -✓✓
Quinine
• Which drug can be used to treat both bacterial infections and malaria? -✓✓
Doxycycline
• Which drug is useful in treating the latent form of Plasmodium ovale infections? -
✓✓ Primaquine
and Answer (2026/2027) | 100% Verified
Answers
• Which drug is active against Gram positive bacteria as well as mycoplasma? -✓✓
Tetracycline
• Which macrolide would be expected to have better patient compliance when
taken orally? -✓✓ Azithromycin
• Which antibiotic may, in some cases, exert its effect inside of human cells? -✓✓
Doxycycline
• An ambulance brings in a patient that is in a non-responsive patient suffering
from sepsis due to a S. aureus infection. You go to administer amoxicillin but
notice that they are wearing a medical bracelet saying that they are allergic to
penicillins. Which drug is the most likely alternative to be used for this patient? -
✓✓ clindamycin
• Which mechanism best describes the cause of gray baby syndrome in the use of
chloramphenicol? -✓✓ The drug is cleared slower from babies than in adults
• What part of the bacterial life cycle is most strongly inhibited by ciprofloxacin? -
✓✓ replication
• In general, do we have more drug options for treating aerobic or anaerobic
bacterial infections? -✓✓ aerobic
• Would isoniazid be expected to increase or decrease the activity of drug-
metabolizing enzymes toward other drugs? -✓✓ decrease
• Two patients that are identical in every way except that one is a slow acetylator
and the other is a fast acetylator of isoniazid are being treated for tuberculosis.
Patient A is receiving 15mg/kg once per week and Patient B is receiving 15mg/kg
three times per week. Which patient is the fast acetylator? -✓✓ Patient B
, • Which bacterial cell function is most directly inhibited by rifampin? -✓✓
Transcription
• What is the primary reason that treatment for mycobacteria infection involves
many drugs taken simultaneously -✓✓ to prevent resistance
• Your physician prescribes you an anti-mycobacterial drug and when you ask how
it works, they say, "I don't know." Assuming the physician is competent, which
drug was likely prescribed? -✓✓ Pyrazinamide
• Does amphotericin B increase or decrease the amount of diffusion that happens
across a fungal cell membrane? -✓✓ increase
• What type of biological molecule does Caspofungin bind to? -✓✓ Protein
• If a 1mg/kg does of amphotericin B kills 25% of present fungus and a 30mg/kg
dose of flucytosine kills 30% of present fungus, what would be a reasonable
amount of fungus to expect to be killed if the two doses are given simultaneously?
-✓✓ 75%
• Which of the following antifungals is available OTC to treat athlete's foot? -✓✓
terbinafine
• Which drug is only used to treat thrush? -✓✓ Nystatin
• What type of molecule is the ultimate target of Flagyl? -✓✓ DNA
• What type of molecule is the ultimate target of chloroquine? -✓✓ Protein
• Which drug is a natural product that can be isolated from the bark of a tree? -✓✓
Quinine
• Which drug can be used to treat both bacterial infections and malaria? -✓✓
Doxycycline
• Which drug is useful in treating the latent form of Plasmodium ovale infections? -
✓✓ Primaquine
