BIOCHEM RUTGERS MURPHY CORRECT
COMPREHENSIVE QUESTIONS AND ANSWERS SURE
A+
✔✔Refsum's disease results from a buildup of ________ in nerve tissue - ✔✔phytanic
acids
✔✔Which of the following is not one of the ketone bodies?
a. acetoacetate
b. b-Hydroxybutyrate
c. b-Methylgiutarate
d. acetone
e. none of the above - ✔✔c. b-Methylgiutarate
✔✔Most eicosanoids are derived from ________ acid. - ✔✔arachidonic
✔✔Prostaglandin synthesis is initiated when cyclooxygenase converts arachidonic acid
into ___________ - ✔✔PGG2
✔✔The intermediates in fatty acid synthesis are linked through a ___________ linkage
to ACP - ✔✔thioester
✔✔Saturated fatty acids containing up to 16 carbon atoms are assembled in the
________ - ✔✔cytoplasm
✔✔Fatty acid synthesis begins with the carboxylation of acetyl CoA to form
____________ - ✔✔malonyl-CoA
✔✔All of the following are enzymatic activities found in fatty acid synthase except?
a. b-ketoacyl-ACP reductase
b. acetyl transacylase
, c. thioesterase
d. lipoxygenase
e. b-hydroxyacyl-ACP dehydrase - ✔✔d. lipoxygenase
✔✔Desaturation of fatty acids involves all of the following except:
a. O2
b. NADH
c. cytochrome b5
d. cytochrome b5 reductase
e. none of the above - ✔✔e. none of the above
✔✔Plant fatty acid synthesis occurs in _________ - ✔✔chloroplasts
✔✔The conversion of acyl-CoA to malonyl-CoA is inhibited by __________
a. glucagon
b. epinephrin
c. palmitoyl-CoA
d. All of the above are correct
e. none of the above - ✔✔d. All of the above are correct
✔✔The conversion of acyl-CoA to acylcarnitine is inhibited by ______ - ✔✔malonyl-CoA
✔✔In conjugation reactions... - ✔✔an insoluble molecule is made soluble by conversion
to a derivative with a water soluble functional group
✔✔In Addison's disease...
a. there is inadequate secretion of glucocorticoids and mineralocorticoids
b. the consumption of licorice improves symptoms
c. treatments include cortisone
d. symptoms include hypoclycemia, dehydration, and low blood pressure
e. All of the above - ✔✔e. All of the above
✔✔Membrane remodeling...
a. requires phospholipase
b. requires acyl transferases
c. occurs only when cells are under stress
d. Both A and B are correct
e. A, B, and C are correct - ✔✔d. Both A and B are correct
✔✔The conversion of phosphatidylethanolamine to phosphatidylcholine requires? -
✔✔SAM
✔✔The sulfatides are synthesized when ___________ reacts with 3-
phosphoadenosine-5'-pyrophosphate - ✔✔galactocerebroside
COMPREHENSIVE QUESTIONS AND ANSWERS SURE
A+
✔✔Refsum's disease results from a buildup of ________ in nerve tissue - ✔✔phytanic
acids
✔✔Which of the following is not one of the ketone bodies?
a. acetoacetate
b. b-Hydroxybutyrate
c. b-Methylgiutarate
d. acetone
e. none of the above - ✔✔c. b-Methylgiutarate
✔✔Most eicosanoids are derived from ________ acid. - ✔✔arachidonic
✔✔Prostaglandin synthesis is initiated when cyclooxygenase converts arachidonic acid
into ___________ - ✔✔PGG2
✔✔The intermediates in fatty acid synthesis are linked through a ___________ linkage
to ACP - ✔✔thioester
✔✔Saturated fatty acids containing up to 16 carbon atoms are assembled in the
________ - ✔✔cytoplasm
✔✔Fatty acid synthesis begins with the carboxylation of acetyl CoA to form
____________ - ✔✔malonyl-CoA
✔✔All of the following are enzymatic activities found in fatty acid synthase except?
a. b-ketoacyl-ACP reductase
b. acetyl transacylase
, c. thioesterase
d. lipoxygenase
e. b-hydroxyacyl-ACP dehydrase - ✔✔d. lipoxygenase
✔✔Desaturation of fatty acids involves all of the following except:
a. O2
b. NADH
c. cytochrome b5
d. cytochrome b5 reductase
e. none of the above - ✔✔e. none of the above
✔✔Plant fatty acid synthesis occurs in _________ - ✔✔chloroplasts
✔✔The conversion of acyl-CoA to malonyl-CoA is inhibited by __________
a. glucagon
b. epinephrin
c. palmitoyl-CoA
d. All of the above are correct
e. none of the above - ✔✔d. All of the above are correct
✔✔The conversion of acyl-CoA to acylcarnitine is inhibited by ______ - ✔✔malonyl-CoA
✔✔In conjugation reactions... - ✔✔an insoluble molecule is made soluble by conversion
to a derivative with a water soluble functional group
✔✔In Addison's disease...
a. there is inadequate secretion of glucocorticoids and mineralocorticoids
b. the consumption of licorice improves symptoms
c. treatments include cortisone
d. symptoms include hypoclycemia, dehydration, and low blood pressure
e. All of the above - ✔✔e. All of the above
✔✔Membrane remodeling...
a. requires phospholipase
b. requires acyl transferases
c. occurs only when cells are under stress
d. Both A and B are correct
e. A, B, and C are correct - ✔✔d. Both A and B are correct
✔✔The conversion of phosphatidylethanolamine to phosphatidylcholine requires? -
✔✔SAM
✔✔The sulfatides are synthesized when ___________ reacts with 3-
phosphoadenosine-5'-pyrophosphate - ✔✔galactocerebroside
