BIOCHEM RUTGERS MURPHY FINAL ALL EXAMS QUESTIONS AND ANSWERS SURE A.pd

BIOCHEM RUTGERS MURPHY FINAL ALL EXAMS
QUESTIONS AND ANSWERS SURE A+
✔✔In an redox reaction, an electron acceptor is - ✔✔converted to an electron donor
with the gain of one or more electrons

✔✔Each turn of the CAC produces how many moles of CO2? - ✔✔2

✔✔Acetyl CoA that is consumed by the CAC is produced from which of the following
biochemical pathways?
a. glycolysis
b. fatty acid oxidation
c. purine catabolism
d. urea cycle
e. both A and B are correct - ✔✔both A and B are correct

✔✔Which of the following is the strongest reducing agent?
a. FADH2 (+ 0.22 V)
b. H2 (+ 0.424 V)
c. cytochrome a * Fe 2+ (-0.29 V)
d. lactate (+0.19 V)
e. H2O (-0.82 V) - ✔✔H2

✔✔Which of the following reacts with the acetyl-CoA to form citrate? - ✔✔oxaloacetate

✔✔The redox reaction in which succinate is converted to fumarate uses FAD rather
than NAD+ because? - ✔✔FAD is a stronger oxidizing agent than NAD+

✔✔Which of the following CAC enzymes are closely regulated?
a. citrate synthase
b. isocitrate dehydrogenase
c. a-ketoglutarate dehydrogenase

,d. both A and B are correct
e. A, B, and C are all correct - ✔✔A, B, and C are all correct

✔✔Which of the following requires GDP? - ✔✔succinyl-CoA to succinate

✔✔How many oxidation steps are there in the CAC? - ✔✔4

✔✔Which of the following is a cofactor for the conversion of succinate to fumarate? -
✔✔FAD

✔✔Which of the following reactions involves a substrate level phosphorylation? -
✔✔succinyl-CoA to succinate

✔✔The carbon skeletons of which of the following can be incorporated directly into the
protein?
a. malate
b. succinate
c. a-ketoglutarate
d. oxaloacetate
e. both C and D are correct - ✔✔both C and D are correct

✔✔Which of the following is a positive effector of isocitrate dehydrogenase? - ✔✔ADP

✔✔Which of the following is not directly required for the activity of pyruvate
dehydrogenase? - ✔✔ATP

✔✔The overall reaction catalyzed by pyruvate dehydrogenase is which of the following?
a. CH3COCHO + NAD+ + CoASH -> CH3CHOSCoA + NADH
b. CH3COCOO- + FAD + CoASH -> CH3COSCoA + FADH2
c. CH3COCOO- + NAD+ + CoASH -> CH3COSCoA + NADH
d. CH3CH(OH)COO- + NADH + CoASH -> CH3CH(OH)COSCoA + NAD+
e. None of the above are correct
...what kind of fresh hell is this - ✔✔c. CH3COCOO- + NAD+ + CoASH -> CH3COSCoA
+ NADH

✔✔The CAC is a component of metabolic respiration, i.e, molecular oxygen is... -
✔✔only indirectly involved in the reactions of the cycle

✔✔The reaction process catalyzed by pyruvate dehydrogenase requires all of the
following except ______ - ✔✔FMN

✔✔All of the following are components of the electron transport chain except
____________ - ✔✔Coenzyme A

, ✔✔The ETC component that transfers electrons directly to oxygen is _________ -
✔✔cytochrome oxidase

✔✔During the oxidation of NADH there are several steps in which DEo' is sufficient for
ATP synthesis. These occur with in complexes... - ✔✔I, III, and IV

✔✔Which of the following molecules inhibits Complex I of the electron transport chain? -
✔✔Amytal

✔✔ATP synthesis and mitochondrial electron transport are coupled by
a. protonmotive force
b. high energy intermediates
c. proton gradient
d. Both A and C are correct
e. A, B, and C are correct - ✔✔d. Both A and C are correct

✔✔Evidence supporting the chemiosmotic theory includes all of the following except -
✔✔the pH of a weakly buffered suspension of mitochondria rises when O2 is added

✔✔Examples of uncouplers include (there are 2) - ✔✔DNP and gramicidin

✔✔In the ATP Synthase the F0 factor
a. has 3 types of subunits
b. possesses the ATPase activity
c. is a transmembrane proton channel
d. Both A and B are correct
e. Both A and C are correct - ✔✔e. Both A and C are correct

✔✔The maximum P/O ratio for FADH2 is ____________ - ✔✔1.5

✔✔The control of aerobic respiration by ______________________________ is
referred to as respiratory control - ✔✔ADP

✔✔The first ROS formed during the reduction of oxygen is ______________ -
✔✔superoxide radical

✔✔The reaction of Fe2+ with H2O2 results in the production of
a. hydroxyl radical
b. hydroxide ion
c. superoxide radical
d. Both A and B are correct
e. Both A and C are correct - ✔✔d. Both A and B are correct