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Omeprazole Answer: T: Antiulcer drug
P:Proton Pump inhibitor
Omeprazole prescription approvals Answer: 4-8 week therapy of:
Active duodenal and gastric ulcers
GERD
Maintenance of erosive esophagitis
Omeprazole OTC uses Answer: Relief of heartburn
Omeprazole most patients are symptom free after how many weeks Answer: 2
Omeprazole off-label uses Answer: Prevent PUD in patients taking NSAID's
Omeprazole takes how long to reach therapeutic levels Answer: 2 hours, can last up to 72
hours
Omeprazole adverse effects Answer: Headache, nausea, diarrhea, rash, abdominal pain
Although rare, blood disorders may occur causing unusual fatigue and weakness
Delayed release omeprazole has been associated with an increased risk of Clostridium
difficile- associated diarrhea in hospitalized patients
Omeprazole Foods to avoid Answer: Ginko & St. John's Wart
Omeprazole is approved for above what age Answer: 2
Ranitidine is administered how & when Answer: PO
Once Daily
Usually at bedtime
Ranitidine usually takes how long to heal ulcer Answer: 4-8 weeks
Ranitidine IV and IM forms are used for what Answer: treatment of acute stress-induced
bleeding ulcers
Ranitidine indications (5) Answer: duodenal ulcers
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,gastric ulcers
hypersecretory conditions
heartburn
GERD
Ranitidine dissolving tablet is used for treating Answer: GERD in children and infants older
than 1 month of age
Ranitidine adverse effects Answer: Are uncommon
Although rare, blood dycrasias, especially neutropenia and thrombocytopenia have been
reported, thus periodic blood counts should be performed
Ranitidine contraindications (3) Answer: acute porphyria
OTC administration in children younger than 12
Used with caution in patients with renal impairment
Ranitidine Drug interactions (4) Answer: Alcohol
Warfari
Antacids within 1 hour
Smoking
Ranitidine herbal/food Answer: May cause vitamin B12 deficiency
May affect iron absorption
Psyllium Mucilloid T & P Answer: Therapeutic: Agent for constipation
P: Bulk-type laxative
Psyllium Mucilloid is derived from what Answer: a natural product- the seeds of the
plantain plant
Psyllium Mucilloid needs to be taken with what Answer: a Sufficient quantity of water
Psyllium Mucilloid may be needed for how long Answer: over 1-3 days. Several doses may
be taken each day
Psyllium Mucilloid Adverse effects Answer: If taken with insufficient water, psyllium may
swell in the esophagus and cause obstruction
Psyllium Mucilloid contraindications (3) Answer: Undiagnosed abdominal pain
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, Suspected intestinal obstruction or,
Fecal importation
Psyllium Mucilloid drug interactions (4) Answer: Warfarin
Digoxin
Nitrofurantoin
Antibiotics
Diphenoxylate with Atropine T & P Answer: T: Antidiarrheal
P: Opioid
Diphenoxylate with Atropine ho long does it take to reach therapeutic effects Answer: 45-
60 minutes
Diphenoxylate with Atropine Indications Answer: moderate to severe diarrhea, but not
recommended for infants
Diphenoxylate with Atropine should be discontinued when Answer: as soon as diarrhea
symptoms resolve
Diphenoxylate with Atropine Adverse effects Answer: Some patients experience dizziness,
lethargy, and drowsiness so should not drive or operate machinery until the effects of the
drug are known
At higher doses the anticholinergic effects of atropine, which include drowsiness, flushing,
dry mouth, tachycardia
Diphenoxylate with Atropine Contraindications (4) Answer: Severe hepatic impairment
Obstructive jaundice
Diarrhea associated with pseudomembranous colitis
Dehydration or electrolyte imbalances should be corrected before diphenoxylate therapy is
initiated
Diphenoxylate with Atropine Drug interactions Answer: Other CNS depressants, including
alcohol,
Naloxone
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LEARN, PRACTICE & EXCEL!
Omeprazole Answer: T: Antiulcer drug
P:Proton Pump inhibitor
Omeprazole prescription approvals Answer: 4-8 week therapy of:
Active duodenal and gastric ulcers
GERD
Maintenance of erosive esophagitis
Omeprazole OTC uses Answer: Relief of heartburn
Omeprazole most patients are symptom free after how many weeks Answer: 2
Omeprazole off-label uses Answer: Prevent PUD in patients taking NSAID's
Omeprazole takes how long to reach therapeutic levels Answer: 2 hours, can last up to 72
hours
Omeprazole adverse effects Answer: Headache, nausea, diarrhea, rash, abdominal pain
Although rare, blood disorders may occur causing unusual fatigue and weakness
Delayed release omeprazole has been associated with an increased risk of Clostridium
difficile- associated diarrhea in hospitalized patients
Omeprazole Foods to avoid Answer: Ginko & St. John's Wart
Omeprazole is approved for above what age Answer: 2
Ranitidine is administered how & when Answer: PO
Once Daily
Usually at bedtime
Ranitidine usually takes how long to heal ulcer Answer: 4-8 weeks
Ranitidine IV and IM forms are used for what Answer: treatment of acute stress-induced
bleeding ulcers
Ranitidine indications (5) Answer: duodenal ulcers
APPHIA – Crafted with Care and Precision for Academic Excellence.
1
,gastric ulcers
hypersecretory conditions
heartburn
GERD
Ranitidine dissolving tablet is used for treating Answer: GERD in children and infants older
than 1 month of age
Ranitidine adverse effects Answer: Are uncommon
Although rare, blood dycrasias, especially neutropenia and thrombocytopenia have been
reported, thus periodic blood counts should be performed
Ranitidine contraindications (3) Answer: acute porphyria
OTC administration in children younger than 12
Used with caution in patients with renal impairment
Ranitidine Drug interactions (4) Answer: Alcohol
Warfari
Antacids within 1 hour
Smoking
Ranitidine herbal/food Answer: May cause vitamin B12 deficiency
May affect iron absorption
Psyllium Mucilloid T & P Answer: Therapeutic: Agent for constipation
P: Bulk-type laxative
Psyllium Mucilloid is derived from what Answer: a natural product- the seeds of the
plantain plant
Psyllium Mucilloid needs to be taken with what Answer: a Sufficient quantity of water
Psyllium Mucilloid may be needed for how long Answer: over 1-3 days. Several doses may
be taken each day
Psyllium Mucilloid Adverse effects Answer: If taken with insufficient water, psyllium may
swell in the esophagus and cause obstruction
Psyllium Mucilloid contraindications (3) Answer: Undiagnosed abdominal pain
APPHIA – Crafted with Care and Precision for Academic Excellence.
2
, Suspected intestinal obstruction or,
Fecal importation
Psyllium Mucilloid drug interactions (4) Answer: Warfarin
Digoxin
Nitrofurantoin
Antibiotics
Diphenoxylate with Atropine T & P Answer: T: Antidiarrheal
P: Opioid
Diphenoxylate with Atropine ho long does it take to reach therapeutic effects Answer: 45-
60 minutes
Diphenoxylate with Atropine Indications Answer: moderate to severe diarrhea, but not
recommended for infants
Diphenoxylate with Atropine should be discontinued when Answer: as soon as diarrhea
symptoms resolve
Diphenoxylate with Atropine Adverse effects Answer: Some patients experience dizziness,
lethargy, and drowsiness so should not drive or operate machinery until the effects of the
drug are known
At higher doses the anticholinergic effects of atropine, which include drowsiness, flushing,
dry mouth, tachycardia
Diphenoxylate with Atropine Contraindications (4) Answer: Severe hepatic impairment
Obstructive jaundice
Diarrhea associated with pseudomembranous colitis
Dehydration or electrolyte imbalances should be corrected before diphenoxylate therapy is
initiated
Diphenoxylate with Atropine Drug interactions Answer: Other CNS depressants, including
alcohol,
Naloxone
APPHIA – Crafted with Care and Precision for Academic Excellence.
3
