Exam (Latest Updates)
Questions & Answers 100% Correct {Grade
A}
Describe the phases of the STRAW (Stage: -1) Late transition - correct answer The
number of remaining oocytes drop below a critical level with sporadic follicular
development resulting in sporadic ovulation. Lower progesterone levels are noted.
Follicular development eventually stops which results in estradiol deficiency.
List the ethnic prevalence of POI in order from greatest to least for patients that are
white, black, hispanic, Japanese, & Chinese. - correct answer Black/Hispanic 1.4%,
White 1%, Chinese 0.5%, and Japanese 0.1%.
What is the cause of earlier mortality in women with surgical menopause <45? -
correct answer CVD
,Increased trunk-mass-to-leg-fat-mass ratio has been associated with what changes
in vitals, and labs? - correct answer Increased blood pressure, fasting glucose, and
abnormal lipoprotein profiles.
Women with increased visceral adipose tissue stores are more likely to suffer from
what comorbidities? - correct answer Cardiometabolic conditions, DM, metabolic
syndrome, hepatic statosis, and aortic plaques.
Obese, postmenopausal women have a _____ rate of breast cancer than
postmenopausal women of normal weights. - correct answer Higher
Obesity and VMS:
Elevated BMI is associated with ____ frequent / _____ VMS during perimenopause.
Higher BMI is associated with _____ VMS when women are postmenopausal. - correct
answer more / severe
fewer
Obesity and hormone values:
,Obese premenopausal / perimenopausal women have _____ estradiol levels than non
obese patients.
Obese postmenopausal women have _____ estradiol levels than non obese patients. -
correct answer Lower / High
What are the effects of androgens on GU health? (2) - correct answer Simulates nerve
fibers and maintains healthy epithelium
Menopause is associated with what body composition changes? - correct answer
Menopause is associated with increase in central adiposity as well as visceral fat and
decrease of lean body mass.
What are the hormonal changes noted with sleep disurbance? - correct answer
Increased cortisol, lower thyrotropin, lower leptin, reduced glucose tolerance
List the risk factors for VMS (5) - correct answer 1) low socioeconomic status
2) low education level
3) obesity (in perimenopause)
, 4) smoking/tobacco use
5) surgical hysterectomy/oophrectomy
VMS are associated with what two adverse health outcomes? - correct answer CVD
and poor bone health
First-line treatment for VMS. - correct answer HT is the first-line. (ET, EPT, ERAAs).
-in women with a uterus, EPT or CEE plus bazedoxifene (an ERAA)
SSRI/SNRI therapy for VMS (5): - correct answer Paroxetine 10-25mg only FDA
approved
Citalopram 10-20mg
Escitalopram 10-20mg
Venlafaxine 37.5mg-150mg
Desvenlafaxine 100-150mg