Pharmacology Exam Prep | Complete Study Guide with Detailed
Rationales | Latest 2026–2027 Update
A 26-Year-Old Woman With Pustular Psoriasis Would Like To Become Pregnant And Start A
Family Within The Next Two Years. Which Agent Should Be Avoided For Treatment Of Her
Psoriasis Because The Duration Of Its Teratogenic Potential May Affect Her Plans For Pregnancy?
A. Triamcinolone Acetonide
B. Infliximab
C. Acitretin
D. Calcipotriene
CORRECT ANS: Acitretin Is Teratogenic, And Women Must Avoid Pregnancy For At Least 3 Years
After The Use Of This Drug (Due To The Long Duration Of Teratogenic Potential).
Which Of The Following Agents Is Used As A Repigmentation Agent For Patients With Vitiligo
That Must Be Photoactivated By Uv Radiation To Form A Dna Adduct Inhibiting Dna Replication
By Psoralen Plus Uva Radiation?
A. Methoxsalen
B. Tazarotene
, C. Hydroquinone
D. Adapalene
CORRECT ANS: Methoxsalen: Methoxsalen Is A Psoralen Photoactive Agent That Stimulates
Melanocytes And Is Used As A Repigmentation Agent For Patients With Vitiligo (Figure 43.7). It
Must Be Photoactivated By Uv Radiation To Form A Dna Adduct Inhibiting Dna Replication By A
Method Called Puva (Psoralen Plus Uva Radiation)
A 33-Year-Old Man Wants To Quickly Get His Plaque Psoriasis In Visible Areas Under Control For
A Planned Trip To Jamaica And Wants To Keep It Under Control For At Least The Remainder Of
The Summer. Which Of The Following Therapeutic Strategies For Psoriasis Would Best Enable
The Patient To Achieve His Goals?
A. Combination Therapy
B. Step-Up Therapy
C. Monotherapy
D. Sequential Therapy
CORRECT ANS: Sequential Therapy Would Likely Be The Best Approach, As Stronger And
Sometimes More Toxic Agents Are Used Initially To Rapidly Clear The Lesions, Followed By Less
Toxic Agents For Maintenance Therapy.