NR 293 PHARMACOLOGY EXAM 1
LATEST SPRING- SUMMER 2026
MULTIPLE CHOICE 100 OUT OF 100
GRADED A
Risks for injury
know that anything can be a possible risk for patient injury
9 rights of medicine administration
right patient, right dose, right medication, right time, right documentation, right route,
right reason, right response
what is a prototype
the first drug of a class that all others are based from (ex- morphine)
what is pharmacokinetics
what the body does to the drug
what is pharmacodynamics
what the drug does to the body
bioavailability
what portion of the drug that entered the circulation can have an effect on the body
first pass effect
a drug enters the GI tract and is filtered to the liver where some is destroyed
what enzymes work in the liver
P-450 enzymes
,if a patient has cirrhosis of the liver, what will happen when they take a
medication?
When the medication passes through the liver for the first pass, there will be less P-450
enzymes so the bioavailability of the medication will be higher and it will circulate in the
bloodstream longer.
half life
time required for 50% of the drug to be removed from the body
Pharmacotherapeutics
treatment of conditions
enteral route
through the GI tract
parenteral tract
outside the GI tract
how is medication absorption different for neonates and children?
they have less gastric acid to break down medications and availability is higher
why do more drugs enter neonate and children's brains, why are meds not as
easily excreted/destroyed by liver and kidneys ?
immature BBB, liver, and kidneys
Polypharmacy
The use of multiple medications on a regular basis
during which phase of the nursing process does a nurse prioritize the nursing
diagnoses?
planning
, the nurse recognizes that drugs given by which route will be altered by the first
pass effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal
oral and rectal
the nurse is reviewing a list of a patient's medications and notes one of the drugs
has a low therapeutic index. what does this mean?
the difference between a therapeutic dose and a toxic dose are very close together
when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what
result of drug B?
level of drug B could rise to toxicity
A drug is highly protein bound, what does this mean?
it will have a longer duration of action
do no harm is what ethical principle?
nonmaleficence
Which legal act required drug manufacturers to establish the safety and efficacy
of a new drug before its approval for use?
Kefauver-Harris, amendment of 1962
over the counter drugs (otc) are
nonprescription drugs that are used for short term treatment
LATEST SPRING- SUMMER 2026
MULTIPLE CHOICE 100 OUT OF 100
GRADED A
Risks for injury
know that anything can be a possible risk for patient injury
9 rights of medicine administration
right patient, right dose, right medication, right time, right documentation, right route,
right reason, right response
what is a prototype
the first drug of a class that all others are based from (ex- morphine)
what is pharmacokinetics
what the body does to the drug
what is pharmacodynamics
what the drug does to the body
bioavailability
what portion of the drug that entered the circulation can have an effect on the body
first pass effect
a drug enters the GI tract and is filtered to the liver where some is destroyed
what enzymes work in the liver
P-450 enzymes
,if a patient has cirrhosis of the liver, what will happen when they take a
medication?
When the medication passes through the liver for the first pass, there will be less P-450
enzymes so the bioavailability of the medication will be higher and it will circulate in the
bloodstream longer.
half life
time required for 50% of the drug to be removed from the body
Pharmacotherapeutics
treatment of conditions
enteral route
through the GI tract
parenteral tract
outside the GI tract
how is medication absorption different for neonates and children?
they have less gastric acid to break down medications and availability is higher
why do more drugs enter neonate and children's brains, why are meds not as
easily excreted/destroyed by liver and kidneys ?
immature BBB, liver, and kidneys
Polypharmacy
The use of multiple medications on a regular basis
during which phase of the nursing process does a nurse prioritize the nursing
diagnoses?
planning
, the nurse recognizes that drugs given by which route will be altered by the first
pass effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal
oral and rectal
the nurse is reviewing a list of a patient's medications and notes one of the drugs
has a low therapeutic index. what does this mean?
the difference between a therapeutic dose and a toxic dose are very close together
when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what
result of drug B?
level of drug B could rise to toxicity
A drug is highly protein bound, what does this mean?
it will have a longer duration of action
do no harm is what ethical principle?
nonmaleficence
Which legal act required drug manufacturers to establish the safety and efficacy
of a new drug before its approval for use?
Kefauver-Harris, amendment of 1962
over the counter drugs (otc) are
nonprescription drugs that are used for short term treatment
