ATI Pharmacology Thyroid and
Adrenal Medications Latest
Practice Questions And
Correct Answers (Verified
Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A patient with hypothyroidism is prescribed
levothyroxine. What is the best instruction?
A. Take the medication with food
B. Take it at bedtime
C. Take it in the morning on an empty stomach
D. Take it with calcium supplements
Answer: C. Take it in the morning on an empty stomach
Rationale: Levothyroxine absorption is best on an empty
stomach, usually 30–60 minutes before breakfast. Food and
calcium reduce absorption.
2. Which finding indicates therapeutic effect of
levothyroxine?
,A. Weight gain
B. Increased energy level
C. Bradycardia
D. Cold intolerance
Answer: B. Increased energy level
Rationale: Improvement in metabolism, energy, and reduced
fatigue indicates effective treatment.
3. A nurse is teaching a patient about methimazole. Which
statement is correct?
A. “It increases thyroid hormone production”
B. “It blocks thyroid hormone synthesis”
C. “It is used for hypothyroidism”
D. “It causes weight gain immediately”
Answer: B. “It blocks thyroid hormone synthesis”
Rationale: Methimazole is an antithyroid medication that
inhibits hormone production.
4. Which lab value is most important to monitor in a patient
taking methimazole?
A. Platelets
B. WBC count
C. Potassium
D. Calcium
,Answer: B. WBC count
Rationale: Methimazole can cause agranulocytosis, leading to
severe infection risk.
5. A patient reports sore throat and fever while on
methimazole. What is the priority action?
A. Give acetaminophen
B. Encourage fluids
C. Hold medication and notify provider
D. Reassure patient
Answer: C. Hold medication and notify provider
Rationale: These are signs of agranulocytosis, a life-
threatening adverse effect.
6. Propylthiouracil (PTU) is preferred in which situation?
A. Long-term hypothyroidism
B. First trimester pregnancy
C. Hypercalcemia
D. Diabetes mellitus
Answer: B. First trimester pregnancy
Rationale: PTU is preferred early in pregnancy due to lower
teratogenic risk.
7. What is a common adverse effect of levothyroxine
overdose?
, A. Bradycardia
B. Hypothermia
C. Tachycardia
D. Weight gain
Answer: C. Tachycardia
Rationale: Excess thyroid hormone causes hypermetabolic
symptoms including tachycardia.
8. A patient receiving radioactive iodine therapy should be
instructed to:
A. Avoid fluids
B. Avoid close contact with others
C. Increase iodine intake
D. Stop all medications permanently
Answer: B. Avoid close contact with others
Rationale: Radioactive iodine emits radiation; patients should
limit exposure to others temporarily.
9. Which condition is treated with levothyroxine?
A. Hyperthyroidism
B. Hypothyroidism
C. Addison’s disease
D. Cushing’s syndrome
Answer: B. Hypothyroidism
Rationale: Levothyroxine replaces deficient thyroid hormone.
Adrenal Medications Latest
Practice Questions And
Correct Answers (Verified
Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A patient with hypothyroidism is prescribed
levothyroxine. What is the best instruction?
A. Take the medication with food
B. Take it at bedtime
C. Take it in the morning on an empty stomach
D. Take it with calcium supplements
Answer: C. Take it in the morning on an empty stomach
Rationale: Levothyroxine absorption is best on an empty
stomach, usually 30–60 minutes before breakfast. Food and
calcium reduce absorption.
2. Which finding indicates therapeutic effect of
levothyroxine?
,A. Weight gain
B. Increased energy level
C. Bradycardia
D. Cold intolerance
Answer: B. Increased energy level
Rationale: Improvement in metabolism, energy, and reduced
fatigue indicates effective treatment.
3. A nurse is teaching a patient about methimazole. Which
statement is correct?
A. “It increases thyroid hormone production”
B. “It blocks thyroid hormone synthesis”
C. “It is used for hypothyroidism”
D. “It causes weight gain immediately”
Answer: B. “It blocks thyroid hormone synthesis”
Rationale: Methimazole is an antithyroid medication that
inhibits hormone production.
4. Which lab value is most important to monitor in a patient
taking methimazole?
A. Platelets
B. WBC count
C. Potassium
D. Calcium
,Answer: B. WBC count
Rationale: Methimazole can cause agranulocytosis, leading to
severe infection risk.
5. A patient reports sore throat and fever while on
methimazole. What is the priority action?
A. Give acetaminophen
B. Encourage fluids
C. Hold medication and notify provider
D. Reassure patient
Answer: C. Hold medication and notify provider
Rationale: These are signs of agranulocytosis, a life-
threatening adverse effect.
6. Propylthiouracil (PTU) is preferred in which situation?
A. Long-term hypothyroidism
B. First trimester pregnancy
C. Hypercalcemia
D. Diabetes mellitus
Answer: B. First trimester pregnancy
Rationale: PTU is preferred early in pregnancy due to lower
teratogenic risk.
7. What is a common adverse effect of levothyroxine
overdose?
, A. Bradycardia
B. Hypothermia
C. Tachycardia
D. Weight gain
Answer: C. Tachycardia
Rationale: Excess thyroid hormone causes hypermetabolic
symptoms including tachycardia.
8. A patient receiving radioactive iodine therapy should be
instructed to:
A. Avoid fluids
B. Avoid close contact with others
C. Increase iodine intake
D. Stop all medications permanently
Answer: B. Avoid close contact with others
Rationale: Radioactive iodine emits radiation; patients should
limit exposure to others temporarily.
9. Which condition is treated with levothyroxine?
A. Hyperthyroidism
B. Hypothyroidism
C. Addison’s disease
D. Cushing’s syndrome
Answer: B. Hypothyroidism
Rationale: Levothyroxine replaces deficient thyroid hormone.
