ATI Pharmacology Sedatives
and Hypnotics Latest Practice
Questions And Correct
Answers
(Verified Answers) Plus
Rationales 2026
Q&A | Instant Download Pdf
1. A nurse is teaching a client about zolpidem. Which
instruction is most important?
A. Take it with a high-fat meal
B. Take it immediately before going to bed
C. Take it in the morning
D. Take it with grapefruit juice
Answer: B
Rationale: Zolpidem is a non-benzodiazepine hypnotic used
for insomnia and should be taken right before sleep to reduce
risk of injury and next-day sedation.
,2. Which medication is classified as a benzodiazepine?
A. Zolpidem
B. Lorazepam
C. Ramelteon
D. Diphenhydramine
Answer: B
Rationale: Lorazepam is a benzodiazepine used for anxiety,
sedation, and seizures.
3. A client receiving midazolam should be monitored for
which priority adverse effect?
A. Hypertension
B. Respiratory depression
C. Hyperactivity
D. Tachycardia
Answer: B
Rationale: Benzodiazepines can cause respiratory depression,
especially when combined with other CNS depressants.
4. Flumazenil is used as an antidote for overdose of:
A. Barbiturates
B. Opioids
C. Benzodiazepines
D. Antidepressants
Answer: C
Rationale: Flumazenil reverses benzodiazepine effects.
,5. A nurse should question an order for zolpidem if the
client has:
A. Insomnia
B. Sleep apnea
C. Anxiety
D. Hypertension
Answer: B
Rationale: Sedative-hypnotics can worsen sleep apnea due to
respiratory depression.
6. Which is a common side effect of benzodiazepines?
A. Weight loss
B. Sedation and drowsiness
C. Hypertension
D. Increased appetite
Answer: B
Rationale: CNS depression causes sedation and drowsiness.
7. Which medication is a barbiturate?
A. Phenobarbital
B. Lorazepam
C. Zolpidem
D. Buspirone
Answer: A
, Rationale: Phenobarbital is a barbiturate used for seizures
and sedation.
8. A major risk of barbiturate use is:
A. Liver failure
B. Severe respiratory depression
C. Hypertension
D. Hyperglycemia
Answer: B
Rationale: Barbiturates strongly depress the CNS and can
suppress breathing.
9. Which instruction is appropriate for a client taking
temazepam?
A. Stop abruptly when sleep improves
B. Avoid alcohol
C. Take with caffeine
D. Increase dose if ineffective
Answer: B
Rationale: Alcohol increases CNS depression and risk of
respiratory suppression.
10. Which drug is a melatonin receptor agonist?
A. Zolpidem
B. Ramelteon
C. Diazepam
and Hypnotics Latest Practice
Questions And Correct
Answers
(Verified Answers) Plus
Rationales 2026
Q&A | Instant Download Pdf
1. A nurse is teaching a client about zolpidem. Which
instruction is most important?
A. Take it with a high-fat meal
B. Take it immediately before going to bed
C. Take it in the morning
D. Take it with grapefruit juice
Answer: B
Rationale: Zolpidem is a non-benzodiazepine hypnotic used
for insomnia and should be taken right before sleep to reduce
risk of injury and next-day sedation.
,2. Which medication is classified as a benzodiazepine?
A. Zolpidem
B. Lorazepam
C. Ramelteon
D. Diphenhydramine
Answer: B
Rationale: Lorazepam is a benzodiazepine used for anxiety,
sedation, and seizures.
3. A client receiving midazolam should be monitored for
which priority adverse effect?
A. Hypertension
B. Respiratory depression
C. Hyperactivity
D. Tachycardia
Answer: B
Rationale: Benzodiazepines can cause respiratory depression,
especially when combined with other CNS depressants.
4. Flumazenil is used as an antidote for overdose of:
A. Barbiturates
B. Opioids
C. Benzodiazepines
D. Antidepressants
Answer: C
Rationale: Flumazenil reverses benzodiazepine effects.
,5. A nurse should question an order for zolpidem if the
client has:
A. Insomnia
B. Sleep apnea
C. Anxiety
D. Hypertension
Answer: B
Rationale: Sedative-hypnotics can worsen sleep apnea due to
respiratory depression.
6. Which is a common side effect of benzodiazepines?
A. Weight loss
B. Sedation and drowsiness
C. Hypertension
D. Increased appetite
Answer: B
Rationale: CNS depression causes sedation and drowsiness.
7. Which medication is a barbiturate?
A. Phenobarbital
B. Lorazepam
C. Zolpidem
D. Buspirone
Answer: A
, Rationale: Phenobarbital is a barbiturate used for seizures
and sedation.
8. A major risk of barbiturate use is:
A. Liver failure
B. Severe respiratory depression
C. Hypertension
D. Hyperglycemia
Answer: B
Rationale: Barbiturates strongly depress the CNS and can
suppress breathing.
9. Which instruction is appropriate for a client taking
temazepam?
A. Stop abruptly when sleep improves
B. Avoid alcohol
C. Take with caffeine
D. Increase dose if ineffective
Answer: B
Rationale: Alcohol increases CNS depression and risk of
respiratory suppression.
10. Which drug is a melatonin receptor agonist?
A. Zolpidem
B. Ramelteon
C. Diazepam
