NURS 5334 Advanced Pharmacology Module 2
exam predictor 2026 Questions and Answers
Save
Practice questions for this set
Learn 1 /7 Study with Learn
abx therapy before causative organism is identified
Choose an answer
infant absorption: oral
1 identification of teratogens 2
administration
adverse reactions during
3 empiric therapy 4
pregnancy
Don't know?
Terms in this set (143)
,identification of teratogens difficult to identify, 3 criteria must be met:
1. The agent must be present during the critical
stage of development
2. The agent produces a particular pattern of
birth defects in animal studies.
3. The agent crosses the placenta and there is a
dose-response relationship.
3 stages of teratogenesis 1. conception through week 2
development 2. embryonic period week 3-8 = gross
malformations
3. fetal period week 9-delivery = functions
disrupted w/ teratogen exposure
physiologic changes during - 3rd trimester = renal blood doubles, renal
pregnancy & drug impact excretion accelerated
- tone and mobility of bowel decreases ->
prolongation of drug effects
placental drug transfer all drugs can cross the placenta, some cross
more easily than others
, adverse reactions during can adversely affect both pregnant pt and fetus
pregnancy - heparin -> osteoporosis
- prostaglandins -> stimulate uterine contraction
- some pain relievers can be used during delivery
can cause respiratory depression in baby
teratogenesis birth defects gross malformations = cleft palate, clubfoot,
hydrocephalus
neurobehavioral & metabolic anomalies
responding to teratogen exposure Determine when the drug was taken
Determine when the pregnancy began
-Weeks 3-8 (organogenesis) is most crucial time
Determine type of malformation expected
Conduct 2 US and consult FDA to determine
severity
how to decrease risk of drug - take drugs immediately after breastfeeding
effects during breastfeeding - avoid drugs w/ long half-lives
- choose drugs that tend to be excluded from
milk, least likely to affect infant
- avoid hazardous drugs
pediatric response to drugs - more sensitive to drugs
- greater individual variation
- sensitivity d/t organ system immaturity
- increased risk for adverse rxns
determining the intensity of - elevated drug levels = more intense response
duration of drug response in - delayed elimination = prolonged response
neonates & infants - immaturity of organs = risk for both^
exam predictor 2026 Questions and Answers
Save
Practice questions for this set
Learn 1 /7 Study with Learn
abx therapy before causative organism is identified
Choose an answer
infant absorption: oral
1 identification of teratogens 2
administration
adverse reactions during
3 empiric therapy 4
pregnancy
Don't know?
Terms in this set (143)
,identification of teratogens difficult to identify, 3 criteria must be met:
1. The agent must be present during the critical
stage of development
2. The agent produces a particular pattern of
birth defects in animal studies.
3. The agent crosses the placenta and there is a
dose-response relationship.
3 stages of teratogenesis 1. conception through week 2
development 2. embryonic period week 3-8 = gross
malformations
3. fetal period week 9-delivery = functions
disrupted w/ teratogen exposure
physiologic changes during - 3rd trimester = renal blood doubles, renal
pregnancy & drug impact excretion accelerated
- tone and mobility of bowel decreases ->
prolongation of drug effects
placental drug transfer all drugs can cross the placenta, some cross
more easily than others
, adverse reactions during can adversely affect both pregnant pt and fetus
pregnancy - heparin -> osteoporosis
- prostaglandins -> stimulate uterine contraction
- some pain relievers can be used during delivery
can cause respiratory depression in baby
teratogenesis birth defects gross malformations = cleft palate, clubfoot,
hydrocephalus
neurobehavioral & metabolic anomalies
responding to teratogen exposure Determine when the drug was taken
Determine when the pregnancy began
-Weeks 3-8 (organogenesis) is most crucial time
Determine type of malformation expected
Conduct 2 US and consult FDA to determine
severity
how to decrease risk of drug - take drugs immediately after breastfeeding
effects during breastfeeding - avoid drugs w/ long half-lives
- choose drugs that tend to be excluded from
milk, least likely to affect infant
- avoid hazardous drugs
pediatric response to drugs - more sensitive to drugs
- greater individual variation
- sensitivity d/t organ system immaturity
- increased risk for adverse rxns
determining the intensity of - elevated drug levels = more intense response
duration of drug response in - delayed elimination = prolonged response
neonates & infants - immaturity of organs = risk for both^
